
NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 407 prodotti di "NF-κB"
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OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Formula:C44H70O16Purezza:99.46% - ≥95%Colore e forma:SolidPeso molecolare:855.02Benzoyloxypaeoniflorin
CAS:Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.Formula:C30H32O13Purezza:98.52% - 99.96%Colore e forma:SolidPeso molecolare:600.57Ref: TM-T4S1658
1mg120,00€5mg281,00€10mg409,00€25mg660,00€50mg888,00€100mg1.224,00€1mL*10mM (DMSO)358,00€Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormula:C19H18NO4Purezza:98.08% - 99.18%Colore e forma:SolidPeso molecolare:324.35Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFormula:C5H12N2S2Purezza:98% - >99.99%Colore e forma:Off-White To Pale Yellow CrystalsPeso molecolare:164.29PTP1B-IN-1
CAS:PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)Formula:C8H8N2O3SPurezza:99.27%Colore e forma:SolidPeso molecolare:212.232-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.
Formula:C11H10N2OSPurezza:99.48%Colore e forma:SolidPeso molecolare:218.27Iron sucrose
CAS:Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.
Formula:C18H24Fe2O24Purezza:99.97%Colore e forma:SolidPeso molecolare:736.1Vanillic Acid
CAS:Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.Formula:C8H8O4Purezza:99.82%Colore e forma:White Odourless Crystals Or PowderPeso molecolare:168.15(E/Z)-IT-603
CAS:(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.Formula:C11H9BrN2O3SPurezza:99.35%Colore e forma:SolidPeso molecolare:329.17Ref: TM-T8799
1mg56,00€5mg119,00€10mg192,00€25mg356,00€50mg565,00€100mg802,00€200mg1.099,00€1mL*10mM (DMSO)133,00€Flaconitine
CAS:Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.
Formula:C36H49NO12Purezza:98% - 99.84%Colore e forma:SolidPeso molecolare:687.7718α-Glycyrrhetinic acid
CAS:18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Formula:C30H46O4Purezza:98.54% - 99.68%Colore e forma:SolidPeso molecolare:470.68MLN120B
CAS:MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).Formula:C19H15ClN4O2Purezza:98.92%Colore e forma:SolidPeso molecolare:366.8Ref: TM-TQ0306
1mg49,00€2mg70,00€5mg96,00€10mg160,00€25mg329,00€50mg567,00€100mg777,00€1mL*10mM (DMSO)116,00€MD2-TLR4-IN-1
CAS:MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.Formula:C22H14Cl2N4OPurezza:97.74%Colore e forma:SolidPeso molecolare:421.28Ref: TM-T7672
1mg58,00€5mg128,00€10mg200,00€25mg344,00€50mg482,00€100mg637,00€200mg858,00€1mL*10mM (DMSO)141,00€Asperulosidic acid
CAS:Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.Formula:C18H24O12Purezza:99.47%Colore e forma:SolidPeso molecolare:432.38Ref: TM-TN1410
1mg127,00€2mg173,00€5mg274,00€10mg455,00€25mg747,00€50mg1.017,00€100mg1.359,00€1mL*10mM (DMSO)303,00€BOT-64
CAS:BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathioleFormula:C15H15NO2SPurezza:99.73%Colore e forma:SolidPeso molecolare:273.35Ref: TM-T8705
1mg50,00€5mg110,00€10mg170,00€25mg323,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)102,00€Galloylpaeoniflorin
CAS:Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.Formula:C30H32O15Purezza:99.82%Colore e forma:SolidPeso molecolare:632.57GSK8612
CAS:GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .Formula:C17H17BrF3N7O2SPurezza:99.68% - 99.99%Colore e forma:SolidPeso molecolare:520.33Cyclo(his-pro)
CAS:Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.Formula:C11H14N4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:234.25Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurezza:98.89% - 99.28%Colore e forma:SolidPeso molecolare:265.25Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purezza:99.13% - 99.92%Colore e forma:SolidPeso molecolare:947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€
