CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 142 prodotti di "CCR"
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ML604086
CAS:ML604086 suppresses CCL1 mediated chemotaxis and enhances intracellular Ca2 concentrations.Formula:C27H32N4O4SPurezza:99.91%Colore e forma:SolidPeso molecolare:508.63CCR2-RA-[R]
CAS:CCR2-RA-[R] is a C-C chemokine receptor type 2 (CCR2) allosteric antagonist (IC50: 103 nM).Formula:C18H19ClFNO3Purezza:99.7%Colore e forma:SolidPeso molecolare:351.8CCX140
CAS:CCX140 (CCX140-B) (CCX140-B) is an antagonist of CCR2.Formula:C20H13ClF3N5O3SPurezza:99.66% - 99.95%Colore e forma:SolidPeso molecolare:495.86AZ084
CAS:AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.Formula:C26H34N4O2Purezza:97.12%Colore e forma:SolidPeso molecolare:434.57Ref: TM-T10425
1mg88,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€200mg1.093,00€1mL*10mM (DMSO)182,00€INCB-9471
CAS:INCB-9471 is a CCR5 antagonist with anti-HIV activity and inhibits the interaction between HIV-1 gp120.Formula:C30H40F3N5O2Purezza:98.80%Colore e forma:SolidPeso molecolare:559.666Leronlimab
CAS:Leronlimab (PRO 140), a humanized IgG4 monoclonal antibody, targets CCR5 to combat HIV and cancer.Purezza:SDS-PAGE:95.0%;SEC-HPLC:99.6%Colore e forma:LiquidPeso molecolare:146.66 kDaJ-113863
CAS:J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM).Formula:C30H37Cl2IN2O2Purezza:95.11%Colore e forma:SolidPeso molecolare:655.44Ref: TM-T11699
1mg56,00€2mg82,00€5mg119,00€10mg160,00€25mg288,00€50mg500,00€100mg718,00€1mL*10mM (DMSO)170,00€RS102895 hydrochloride
CAS:RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formula:C21H22ClF3N2O2Purezza:98.95%Colore e forma:SolidPeso molecolare:426.86Mogamulizumab
CAS:<p>Mogamulizumab is a monoclonal antibody targeting CC chemokine receptor 4 with anticancer effects, used in ATLL and CTCL studies.</p>Purezza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Colore e forma:LiquidPeso molecolare:146.43 kDaMK-0812 Succinate
CAS:MK-0812 Succinate is an effective and selective CCR2 antagonist.Formula:C28H40F3N3O7Purezza:98.62% - 99.93%Colore e forma:SolidPeso molecolare:587.63CAP-100
CAP-100 is a monoclonal antibody targeting CCR7. It neutralizes the ligand binding site and signaling of CCR7. This compound effectively inhibits migration, extravasation, homing, and survival in chronic lymphocytic leukemia (CLL) samples induced by CCR7. CAP-100 can mediate potent tumor cell killing through host immune mechanisms and exhibits favorable toxicity profiles in related hematopoietic cell subsets. It is involved in research on antitumor activity and diseases like chronic lymphocytic leukemia (CLL).Colore e forma:Odour LiquidMLN-3897 TFA
MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.Formula:C32H32ClF3N2O6Purezza:98.62%Colore e forma:SolidPeso molecolare:633.05Ref: TM-T28072L
1mg115,00€5mg245,00€10mg363,00€25mg562,00€50mg775,00€100mg1.035,00€200mg1.406,00€1mL*10mM (DMSO)Prezzo su richiestaMet-RANTES,human,acetate
Met-RANTES (human) acetate is the acetate salt form of Met-RANTES (human). It acts as an antagonist for CCR1 and CCR5 receptors. This compound inhibits the human chemokines MIP-1α and MIP-1β, with respective IC50 values of 5 and 2 nM. Additionally, Met-RANTES (human) acetate reduces bone destruction and alleviates adjuvant-induced arthritis (AIA) in rats.Colore e forma:Odour SolidINCB 3284 dimesylate
CAS:INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Formula:C28H39F3N4O10S2Purezza:98%Colore e forma:SolidPeso molecolare:712.76BMS-753426
CAS:<p>BMS-753426 is a potent and orally bioavailable antagonist of CCR2 .</p>Formula:C25H33F3N6O2Colore e forma:SolidPeso molecolare:506.574INCB3344 R-isomer
INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.Formula:C29H34F3N3O6Purezza:98%Colore e forma:SolidPeso molecolare:577.59Bertilimumab
CAS:<p>Bertilimumab (CAT 213; iCo-008), a human monoclonal antibody that targets eotaxin-1 (CCL11), shows promise in the research of allergic disorders [1].</p>Colore e forma:LiquidCCR4 antagonist 3
CAS:Orally active CCR4 antagonist with piperidinyl-azetidine; IC50: 22 nM (calcium flux), 50 nM (CTX); antitumor effects.Formula:C24H27Cl2N7OColore e forma:SolidPeso molecolare:500.43CCR4 antagonist 3 hydrochloride
CAS:Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.Formula:C24H27Cl2N7O·xHClColore e forma:SolidZn-DPA-maytansinoid conjugate 1
Zn-DPA-maytansinoid 1 targets checkpoints, shrinks tumors, and heats TME.Formula:C115H145ClN18O31S2Zn2Colore e forma:SolidPeso molecolare:2505.83Maceneolignan H
CAS:Maceneolignan H, a neolignane from Myristica fragrans, selectively blocks CCR3 (EC50=1.4μM) with allergy research potential.Formula:C24H30O7Colore e forma:SolidPeso molecolare:430.49PF-232798
CAS:PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.Formula:C29H40FN5O2Colore e forma:SolidPeso molecolare:509.66CKLF1-C27 TFA
CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.Formula:C153H244F3N39O39Colore e forma:SolidPeso molecolare:3310.8SQA1
CAS:SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.Formula:C22H26N4O5Colore e forma:SolidPeso molecolare:426.47CCR8 antagonist 1
CAS:CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.Formula:C26H29N3O5SPurezza:99.51%Colore e forma:SolidPeso molecolare:495.59Plozalizumab
CAS:<p>Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of</p>Purezza:96.4%Colore e forma:LiquidPeso molecolare:146.02 kDaCH-0076989
CAS:CH-0076989 is a chemokine receptor CCR3 agonist.Formula:C24H22Br2N2O2Colore e forma:SolidPeso molecolare:530.25CCR6 antagonist 2
CCR6 antagonist2 (Compound 20c) acts as a CCR6 antagonist with a Ki of 1.1 nM. It inhibits CCL20-induced calcium influx with an IC50 of 4.9 nM and suppresses the chemotactic migration of CCR6+ T cells with an IC50 of 190 nM.Formula:C19H24N4O4Colore e forma:SolidPeso molecolare:372.42CHS-114
CHS-114 (SRF-114) is a fully human IgG1 antibody targeting the (CCR8) receptor. It shows potential for research in head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can be referred to as HumanIgG1kappa, Isotype Control.Colore e forma:Odour LiquidCMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-Colore e forma:Odour SolidHGS101
HGS101 is a fully humanized CCR5 monoclonal antibody that exhibits high affinity for CCR5. It binds to the second extracellular loop (ECL-2) and functions as a signaling antagonist. HGS101 restores the inhibitory effect of Maraviroc in Maraviroc-resistant HIV-1 infected PBMCs. In an uninfected simian immunodeficiency virus model of rhesus monkeys, HGS101 shows anti-HIV activity by inhibiting CCR5 signaling.Colore e forma:Odour LiquidCCR6 antagonist 1
CAS:<p>CCR6 antagonist 1 blocks CCL20/CCR6, aiding autoimmune and IBD research.</p>Formula:C17H12F3NO2Purezza:99.83%Colore e forma:SoildPeso molecolare:319.28WAY-639418
CAS:WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.Formula:C17H16ClN5Purezza:99.89%Colore e forma:SolidPeso molecolare:325.8Chemokine Inhibitor Library
<p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>Colore e forma:Odour Solid2-Methoxyhydroquinone
CAS:2-Methoxyhydroquinone inhibits MAO-A and MAO-B and reduces TNF-α-induced CCL2 production, a precursor for synthesising the Hsp90 inhibitor Geldanamycin.Formula:C7H8O3Purezza:98.25%Colore e forma:SolidPeso molecolare:140.14CCR6 inhibitor 1
CAS:<p>CCR6 inhibitor 1 selectively blocks CCR6 (0.45 nM in monkeys, 6 nM in humans), aiding in vitro/vivo disease studies.</p>Formula:C24H23F3N4O3SPurezza:99.89%Colore e forma:SolidPeso molecolare:504.52Cafelkibart
Cafelkibart is a chimeric IgG1κ monoclonal antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Colore e forma:Odour LiquidNebokitug
Nebokitug is a humanized IgG1κ antibody targeting CCL24, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Colore e forma:Odour LiquidAzirkitug
Azirkitug is a humanized IgG1κ antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.Colore e forma:Odour LiquidDenrakibart
Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.Colore e forma:Odour LiquidLanerkitug
Lanerkitug is a humanized IgG1λ2 antibody that targets CCR8, with HumanIgG1lambda2, Isotype Control serving as its corresponding isotype control.Colore e forma:Odour LiquidDenikitug
Denikitug is a chimeric antibody of the IgG1κ type that targets CCR8, with its corresponding isotype control being HumanIgG1kappa, Isotype Control.Colore e forma:Odour LiquidCCR2 antagonist 1
CAS:CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Formula:C28H32BrF3N2OColore e forma:SolidPeso molecolare:549.47NI-0701
NI-0701 is a humanized antibody targeting CCL5/RANTES.Purezza:95.4% (SDS-PAGE); 99.4% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.5kDaCCR8 agonist 1
CCR8 agonist1 (Compound 2) is an activator of CCR8 and is applicable in studies related to autoimmune diseases.Formula:C22H29NO3Colore e forma:SolidPeso molecolare:355.47Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Formula:C19H20N2O3Purezza:98.35% - 98.55%Colore e forma:SolidPeso molecolare:324.37Ref: TM-T6413
1mg38,00€2mg49,00€5mg80,00€10mg116,00€25mg188,00€50mg330,00€100mg520,00€200mgPrezzo su richiesta1mL*10mM (DMSO)88,00€AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Formula:C11H9Cl2N3O3SPurezza:99.80% - >99.99%Colore e forma:SolidPeso molecolare:334.18Ref: TM-T4300
1mg35,00€5mg70,00€10mg111,00€25mg230,00€50mg354,00€100mg530,00€500mg1.121,00€1mL*10mM (DMSO)78,00€Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Formula:C28H38F3N5O2Colore e forma:SolidPeso molecolare:533.63Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColore e forma:SolidPeso molecolare:467.92RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purezza:98.64% - 99.62%Colore e forma:SolidPeso molecolare:417.5SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Formula:C18H18N2O5Purezza:99.59%Colore e forma:SolidPeso molecolare:342.35R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Formula:C21H27NO4Purezza:99.03%Colore e forma:SolidPeso molecolare:357.44Ref: TM-T24700
1mg43,00€2mg56,00€5mg85,00€10mg124,00€25mg220,00€50mg350,00€100mg522,00€1mL*10mM (DMSO)95,00€Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Formula:C41H52N4O4SPurezza:97.87%Colore e forma:SolidPeso molecolare:696.94Ref: TM-TQ0297
1mg63,00€2mg90,00€5mg133,00€10mg212,00€25mg423,00€50mg550,00€100mg715,00€200mg964,00€1mL*10mM (DMSO)200,00€BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Formula:C25H40N8O2Purezza:99.66% - 99.79%Colore e forma:SolidPeso molecolare:484.64Ref: TM-T4584
1mg63,00€5mg137,00€10mg187,00€25mg341,00€50mg567,00€100mg810,00€500mg1.644,00€1mL*10mM (DMSO)145,00€DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Formula:C35H56N10O15Purezza:>99.99%Colore e forma:SolidPeso molecolare:856.88Vicriviroc maleate
CAS:<p>Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.</p>Formula:C32H42F3N5O6Purezza:98.16% - 98.37%Colore e forma:SolidPeso molecolare:649.7PF-4136309
CAS:PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.Formula:C29H31F3N6O3Purezza:98.85% - 99.47%Colore e forma:SolidPeso molecolare:568.597,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Formula:C15H10O4Purezza:99.39% - 99.6%Colore e forma:SolidPeso molecolare:254.24ZK 756326
CAS:ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.Formula:C21H28N2O3Purezza:99.43%Colore e forma:SolidPeso molecolare:356.46RE-640
CAS:NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.Formula:C20H16Cl2N4Purezza:99.60% - 99.87%Colore e forma:SolidPeso molecolare:383.27CCR2 antagonist 4 hydrochloride
CAS:CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).Formula:C21H22Cl2F3N3O2Colore e forma:SolidPeso molecolare:476.32C-021
CAS:C 021 dihydrochloride is a potent CCR4 antagonist.Formula:C27H41N5O2Purezza:99.74% - 99.90%Colore e forma:SolidPeso molecolare:467.65Ref: TM-T21870
1mg51,00€2mg71,00€5mg96,00€10mg153,00€25mg303,00€50mg469,00€100mg655,00€1mL*10mM (DMSO)96,00€Maraviroc
CAS:Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.Formula:C29H41F2N5OPurezza:97.13% - 99.59%Colore e forma:Brown SolidPeso molecolare:513.67Ref: TM-T6016
5mg51,00€10mg95,00€25mg160,00€50mg273,00€100mg492,00€200mg633,00€500mg998,00€1mL*10mM (DMSO)59,00€Vercirnon
CAS:Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.Formula:C22H21ClN2O4SPurezza:99.23%Colore e forma:SolidPeso molecolare:444.93Ref: TM-T17225
1mg105,00€5mg259,00€10mg406,00€25mg680,00€50mg938,00€100mg1.301,00€500mg2.593,00€1mL*10mM (DMSO)363,00€AZD-4818
CAS:AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.Formula:C27H32Cl2N2O7Purezza:99.01%Colore e forma:SolidPeso molecolare:567.46RS102895
CAS:RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.Formula:C21H21F3N2O2Purezza:97.64% - 99.80%Colore e forma:SolidPeso molecolare:390.4TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Formula:C33H39ClN2O2Purezza:99.21%Colore e forma:SolidPeso molecolare:531.13BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Formula:C21H24ClFN4O3Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:434.89Ref: TM-T2375
1mg38,00€5mg90,00€10mg124,00€25mg212,00€50mg329,00€100mg515,00€200mg782,00€1mL*10mM (DMSO)90,00€INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purezza:97.81% - 99.42%Colore e forma:SolidPeso molecolare:520.54Carlumab
CAS:Carlumab is a high-affinity human monoclonal antibody that targets CCL2, suppressing the recruitment of monocytes/macrophages in the tumour microenvironment.Purezza:95%Colore e forma:LiquidPeso molecolare:144.87 kDaTivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFormula:C24H27Cl2F3N6OPurezza:99.88%Colore e forma:SolidPeso molecolare:543.41Ref: TM-T69834
1mg174,00€5mg440,00€10mg704,00€25mg1.407,00€50mg2.186,00€100mg3.039,00€1mL*10mM (DMSO)519,00€CCR1 antagonist 9
CAS:CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.Formula:C20H16FN5O3SPurezza:99.13%Colore e forma:SolidPeso molecolare:425.44Ref: TM-T10710
1mg107,00€5mg254,00€10mg425,00€25mg768,00€50mg1.103,00€100mg1.610,00€1mL*10mM (DMSO)280,00€TAK-220
CAS:TAK-220: Oral CCR5 antagonist. IC50: 3.5 nM (RANTES), 1.4 nM (MIP-1α).Formula:C31H41ClN4O3Purezza:98%Colore e forma:SolidPeso molecolare:553.14MLN3126
CAS:MLN3126: Oral CCR9 blocker, hinders CCL25-triggered chemotaxis/thymocyte calcium influx, IC50 of 6.3 nM.Formula:C21H19ClN2O5SColore e forma:SolidPeso molecolare:446.9AZD-1678
CAS:AZD-1678 is a potent CCR4 receptor antagonist.Formula:C11H8Cl2FN3O3SColore e forma:SolidPeso molecolare:352.17ALK4290
CAS:ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.Formula:C27H34ClN5O3Colore e forma:SolidPeso molecolare:512.04RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Formula:C27H34Cl3N5O2Colore e forma:SolidPeso molecolare:566.95CCR8 antagonist 2
CAS:CCR8 antagonist 2 blocks CCR8 activity, mainly on Treg and Th2 cells, for treating related diseases. See WO2022000443A1, compound 220.Formula:C23H30ClN3O3SColore e forma:SolidPeso molecolare:464.02CCR2 antagonist 3
CAS:CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.Formula:C17H25FN2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:308.39Ref: TM-T10712
1mg70,00€5mg156,00€10mg239,00€25mg419,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)170,00€BI-6901
CAS:BI-6901 is a CCR10 antagonist. In a mouse model of DNFB exposure hypersensitivity, BI 6901 displays its anti-inflammatory response in a dose-dependent manner.Formula:C23H27N5O3SPurezza:99.83%Colore e forma:SolidPeso molecolare:453.56PNU-177864 hydrochloride
CAS:<p>PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.</p>Formula:C18H22ClF3N2O3SPurezza:99.95%Colore e forma:SolidPeso molecolare:438.89PNU-177864
CAS:PNU-177864 is a selective dopamine D3 receptor antagonist.Formula:C18H21F3N2O3SPurezza:99.92%Colore e forma:SolidPeso molecolare:402.43CCR4 antagonist 3-1
CAS:<p>CCR4 antagonist 3-1 is a weak inhibitor of [125I]TARC binding and CEM cell migration, with IC50 values of 1.7 μM and 6.4 μM, respectively.</p>Formula:C14H12N2SPurezza:99.53%Colore e forma:SolidPeso molecolare:240.32C-021 dihydrochloride
CAS:C-021 dihydrochloride is a potent CCR4 antagonist. It potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM.Formula:C27H43Cl2N5O2Purezza:98.67%Colore e forma:SolidPeso molecolare:540.57CCX354
CAS:CCX354 (CCR1 antagonist 1) is a potent small molecule CCR1 antagonist with anti-inflammatory activity for the treatment of rheumatoid arthritis.Formula:C22H22ClN7O2Purezza:99.43% - 99.44%Colore e forma:SolidPeso molecolare:451.91APC-3316 tosylate
CAS:APC-3316 tosylate is a vinyl sulfone cysteine protease inhibitor and selective CCR4 antagonist.Formula:C39H46N4O7S2Colore e forma:SolidPeso molecolare:746.94YM022
CAS:YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.Formula:C32H28N4O3Purezza:98%Colore e forma:SolidPeso molecolare:516.59CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Formula:C21H24ClN5O3SPurezza:98%Colore e forma:SolidPeso molecolare:461.96BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Formula:C24H35ClN2O4Purezza:98%Colore e forma:SolidPeso molecolare:451GW 766994
CAS:GW 766994 is a specific and oral chemokine receptor-3 (CCR3) antagonist. It has the potential for asthma and eosinophilic bronchitis treatment.Formula:C21H24Cl2N4O3Purezza:98.77%Colore e forma:SolidPeso molecolare:451.35JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Formula:C17H15F2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:379.38Tanimilast
CAS:Tanimilast (CHF-6001) is a potent PDE4 inhibitor with IC50 of 0.026 nM, used topically for obstructive lung disease.Formula:C30H30Cl2F2N2O8SPurezza:99.18%Colore e forma:SolidPeso molecolare:687.54BMS-817399
CAS:BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.Formula:C23H36ClN3O4Purezza:99.7%Colore e forma:SolidPeso molecolare:454Ref: TM-T26861
1mg152,00€5mg319,00€10mg485,00€25mg770,00€50mg1.035,00€100mg1.395,00€1mL*10mM (DMSO)356,00€BMS CCR2 22
CAS:BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.Formula:C28H34F3N5O4SPurezza:99.65%Colore e forma:SolidPeso molecolare:593.66Ref: TM-T14688
1mg58,00€5mg116,00€10mg183,00€25mg368,00€50mg562,00€100mg758,00€200mg1.017,00€1mL*10mM (DMSO)156,00€CCR2 antagonist 5
CAS:JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation & diabetes.Formula:C22H25F3N4O3SPurezza:99.98%Colore e forma:SolidPeso molecolare:482.52SB 328437
CAS:SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).Formula:C21H18N2O5Purezza:99.54%Colore e forma:SolidPeso molecolare:378.38Ref: TM-T23321
1mg39,00€5mg82,00€10mg123,00€25mg250,00€50mg394,00€100mg618,00€200mg874,00€1mL*10mM (DMSO)69,00€Cosalane
CAS:Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.Formula:C45H60Cl2O6Purezza:99.53% - 99.78%Colore e forma:SolidPeso molecolare:767.86CCR1 antagonist 6
CAS:<p>CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).</p>Formula:C21H23ClN4O3SPurezza:99.02% - 99.15%Colore e forma:SolidPeso molecolare:446.95GSK2239633A
CAS:GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.Formula:C24H25ClN4O5S2Purezza:99.82%Colore e forma:SolidPeso molecolare:549.06Ref: TM-T11481
1mg35,00€5mg79,00€10mg118,00€25mg245,00€50mg355,00€100mg515,00€500mgPrezzo su richiesta1mL*10mM (DMSO)87,00€Ancriviroc
CAS:Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.Formula:C28H37BrN4O3Purezza:99.76% - 99.82%Colore e forma:SolidPeso molecolare:557.533
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