CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 136 prodotti di "CCR"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Plozalizumab
CAS:<p>Plozalizumab (MLN-1202) is a humanized selective and potent anti-CCR2 antibody.Plozalizumab has antitumor activity.Plozalizumab is used in the study of</p>Purezza:96.4%Colore e forma:LiquidPeso molecolare:146.02 kDaWAY-639418
CAS:<p>WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.</p>Formula:C17H16ClN5Purezza:99.62%Colore e forma:SolidPeso molecolare:325.8Azirkitug
<p>Azirkitug is a humanized IgG1κ antibody targeting CCR8, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.</p>Colore e forma:Odour LiquidVercirnon
CAS:<p>Vercirnon (Traficet-EN) is a selective and potent antagonist of CCR9 (IC50: 10 nM). It is also used in the research of inflammatory bowel diseases.</p>Formula:C22H21ClN2O4SPurezza:99.23%Colore e forma:SolidPeso molecolare:444.93DAPTA
CAS:<p>DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.</p>Formula:C35H56N10O15Purezza:>99.99%Colore e forma:SolidPeso molecolare:856.88BMS-813160
CAS:<p>BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.</p>Formula:C25H40N8O2Purezza:99.66% - 99.79%Colore e forma:SolidPeso molecolare:484.64AZD-4818
CAS:<p>AZD-4818 (CCR1 antagonist) is a chemokine CCR1 antagonist for the treatment of chronic obstructive pulmonary disease.</p>Formula:C27H32Cl2N2O7Purezza:99.01%Colore e forma:SolidPeso molecolare:567.46SB297006
CAS:<p>SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.</p>Formula:C18H18N2O5Purezza:99.59%Colore e forma:SolidPeso molecolare:342.35Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Formula:C22H21ClN2NaO4SColore e forma:SolidPeso molecolare:467.92Cenicriviroc
CAS:<p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>Formula:C41H52N4O4SPurezza:97.87%Colore e forma:SolidPeso molecolare:696.94Bindarit
CAS:<p>Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.</p>Formula:C19H20N2O3Purezza:98.35% - 98.55%Colore e forma:SolidPeso molecolare:324.37RE-640
CAS:<p>NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.</p>Formula:C20H16Cl2N4Purezza:99.60% - 99.87%Colore e forma:SolidPeso molecolare:383.27Vicriviroc maleate
CAS:<p>Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus.</p>Formula:C32H42F3N5O6Purezza:98.16% - 98.37%Colore e forma:SolidPeso molecolare:649.77,4'-Dihydroxyflavone
CAS:<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formula:C15H10O4Purezza:99.39% - 99.6%Colore e forma:SolidPeso molecolare:254.24RS102895
CAS:<p>RS102895 is a potent CCR2 antagonist (IC50: 360 nM) and shows no effect on CCR1.</p>Formula:C21H21F3N2O2Purezza:97.64% - 99.80%Colore e forma:SolidPeso molecolare:390.4CCR2 antagonist 4 hydrochloride
CAS:<p>CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).</p>Formula:C21H22Cl2F3N3O2Colore e forma:SolidPeso molecolare:476.32RS 504393
CAS:RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 μM for human recombinant CCR2 and CCR1).Formula:C25H27N3O3Purezza:98.64% - 99.62%Colore e forma:SolidPeso molecolare:417.5PF-4136309
CAS:<p>PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.</p>Formula:C29H31F3N6O3Purezza:98.85% - 99.47%Colore e forma:SolidPeso molecolare:568.59BX471
CAS:<p>BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.</p>Formula:C21H24ClFN4O3Purezza:98% - 99.94%Colore e forma:SolidPeso molecolare:434.89ZK 756326
CAS:<p>ZK 756326: Selective CCR8 agonist, IC50 1.8 μM (human), 2.6 μM (mouse), no CCR4/5, CXCR3/4 action, 28-fold selectivity vs 26 GPCRs, anti-HIV fusion.</p>Formula:C21H28N2O3Purezza:99.43%Colore e forma:SolidPeso molecolare:356.46
