CCR
I recettori delle chemochine C-C (CCR) sono un gruppo di GPCR che rispondono alle chemochine, molecole segnalatrici che guidano la migrazione delle cellule immunitarie verso i siti di infiammazione o infezione. I CCR svolgono ruoli cruciali nelle risposte immunitarie, nell'infiammazione e nello sviluppo di varie malattie, tra cui disturbi autoimmuni e cancro. La modulazione dell'attività dei CCR è esplorata come strategia terapeutica per condizioni come l'artrite reumatoide, la sclerosi multipla e l'infezione da HIV. Presso CymitQuimica, offriamo una gamma di modulatori CCR di alta qualità per supportare la tua ricerca in immunologia, infiammazione e sviluppo terapeutico.
Trovati 136 prodotti di "CCR"
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CCR1 antagonist 9
CAS:<p>CCR1 antagonist 9 (compound 19e) is a selective CCR1 antagonist based on aziridine. CCR1 inhibition in calcium flux assays.</p>Formula:C20H16FN5O3SPurezza:99.13%Colore e forma:SolidPeso molecolare:425.44CCR2 antagonist 3
CAS:<p>CCR2 antagonist 3 (AZD-2927) is an antagonist of CCR2.</p>Formula:C17H25FN2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:308.39RPT193
CAS:RPT193 is an oral CCR4 inhibitor reducing Th2 cell migration in atopic dermatitis, asthma, and allergies.Formula:C27H34Cl3N5O2Colore e forma:SolidPeso molecolare:566.95ALK4290
CAS:<p>ALK4290 (AKST4290), a potent oral CCR3 inhibitor with a Ki of 3.2 nM, may treat macular degeneration and Parkinsonism.</p>Formula:C27H34ClN5O3Colore e forma:SolidPeso molecolare:512.04AZD-1678
CAS:<p>AZD-1678 is a potent CCR4 receptor antagonist.</p>Formula:C11H8Cl2FN3O3SColore e forma:SolidPeso molecolare:352.17YM022
CAS:<p>YM022 is a highly effective and selective gastrin/cholecystokinin (CCK)-B receptor antagonist.</p>Formula:C32H28N4O3Purezza:98%Colore e forma:SolidPeso molecolare:516.59PNU-177864 hydrochloride
CAS:<p>PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.</p>Formula:C18H22ClF3N2O3SPurezza:99.95%Colore e forma:SolidPeso molecolare:438.89CCR2 antagonist 5
CAS:<p>JNJ-41443532: oral hCCR2 antagonist, IC50=37 nM, anti-chemotaxis, treats inflammation & diabetes.</p>Formula:C22H25F3N4O3SPurezza:99.09%Colore e forma:SolidPeso molecolare:482.52Cosalane
CAS:<p>Cosalane (NSC 658586) is an HIV replication inhibitor and an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice.</p>Formula:C45H60Cl2O6Purezza:99.53% - 99.78%Colore e forma:SolidPeso molecolare:767.86SB 328437
CAS:<p>SB 328437 ((S)-methyl 2-(1-naphthamido)-3-(4-nitrophenyl)propanoate) is an effective and selective antagonist of CCR3 (IC50 = 4.5 nM).</p>Formula:C21H18N2O5Purezza:99.54%Colore e forma:SolidPeso molecolare:378.38BMS CCR2 22
CAS:BMS CCR2 22 is a potent and selective antagonist of CCR2 with calcium flux IC50 of 18 nM, chemotaxis IC50 of 1 nM, and binding IC50 of 5.1 nM.Formula:C28H34F3N5O4SPurezza:99.65%Colore e forma:SolidPeso molecolare:593.66CCR1 antagonist 6
CAS:<p>CCR1 antagonist 6 is a CCR1 antagonist (IC50: 3 nM).</p>Formula:C21H23ClN4O3SPurezza:99.02% - 99.15%Colore e forma:SolidPeso molecolare:446.95GSK2239633A
CAS:<p>GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4.</p>Formula:C24H25ClN4O5S2Purezza:99.82%Colore e forma:SolidPeso molecolare:549.06BMS-817399
CAS:<p>BMS-817399: oral CCR1 antagonist with binding and chemotaxis inhibition IC50s, potential for rheumatoid arthritis research.</p>Formula:C23H36ClN3O4Purezza:99.7%Colore e forma:SolidPeso molecolare:454Ancriviroc
CAS:<p>Ancriviroc (SCH-351125) is an orally bioavailable small molecule chemokine receptor CCR5 antagonist.Cost-effective and quality-assured.</p>Formula:C28H37BrN4O3Purezza:99.76% - 99.82%Colore e forma:SolidPeso molecolare:557.52trans-J-113863
CAS:<p>Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].</p>Formula:C30H37Cl2IN2O2Colore e forma:SolidPeso molecolare:655.44cis-J-113863
CAS:<p>Cis-J-113863 is a competitive antagonist for the chemokine receptor 1 (CCR1), demonstrating inhibitory concentration 50 (IC50) values of 0.9 nM for human CCR1 receptors and 5.8 nM for mouse CCR1 receptors, respectively [1].</p>Formula:C30H37Cl2IN2O2Colore e forma:SolidPeso molecolare:655.44CCR4 antagonist 4
CAS:<p>CCR4 Antagonist 4 (Compound 22) is a potent and selective antagonist of the CC chemokine receptor-4 (CCR4), displaying an IC50 value of 0.02 μM. It also inhibits MDC-mediated chemotaxis and Ca2+ mobilization, with IC50 values of 0.007 μM and 0.003 μM, respectively. This compound is utilized in research on allergic inflammation [1].</p>Formula:C24H27Cl2N7OColore e forma:SolidPeso molecolare:500.42BMS-639623
CAS:<p>BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.</p>Formula:C25H32FN7O2Colore e forma:SolidPeso molecolare:481.57CCR2 antagonist 4
CAS:<p>CCR2 antagonist 4 (Teijin compound 1) is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM</p>Formula:C21H21ClF3N3O2Purezza:99.86%Colore e forma:SolidPeso molecolare:439.86
