CXCR
I CXCR sono una sottoclasse di GPCR che si legano alle chemochine, piccole proteine segnale che guidano il movimento delle cellule immunitarie verso i siti di infiammazione, infezione o lesione. I CXCR svolgono ruoli cruciali nelle risposte immunitarie, nella metastasi del cancro e nelle malattie infiammatorie. I modulatori dei CXCR sono studiati per il loro potenziale nel trattamento delle malattie autoimmuni, del cancro e delle condizioni infiammatorie croniche. Presso CymitQuimica, offriamo una gamma di modulatori di CXCR di alta qualità per supportare la tua ricerca in immunologia, oncologia e infiammazione.
Trovati 159 prodotti di "CXCR"
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Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Formula:C19H20O5Purezza:97.22% - 99.91%Colore e forma:SolidPeso molecolare:328.36Ref: TM-T3S1416
1mg43,00€5mg88,00€10mg119,00€25mg259,00€50mg462,00€100mg662,00€500mg1.359,00€1mL*10mM (DMSO)87,00€AZD-5069
CAS:AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).Formula:C18H22F2N4O5S2Purezza:98.38% - 98.63%Colore e forma:SolidPeso molecolare:476.52Ref: TM-T7681
1mg37,00€2mg49,00€5mg70,00€10mg103,00€25mg202,00€50mg311,00€100mg472,00€200mgPrezzo su richiesta1mL*10mM (DMSO)78,00€Nicotinamide N-oxide
CAS:Nicotinamide N-oxide, a metabolite of nicotinamide and precursor to NAD+, is reduced by liver enzyme xanthine oxidase.Formula:C6H6N2O2Purezza:99.66% - 99.9%Colore e forma:SolidPeso molecolare:138.12AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Formula:C21H28ClN5Purezza:98.38% - 98.57%Colore e forma:SolidPeso molecolare:385.93Alirocumab
CAS:Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.Purezza:95% - 97.1% (SDS-PAGE); 96.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.2 kDaSB-265610
CAS:SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.Formula:C14H9BrN6OPurezza:99.5%Colore e forma:SolidPeso molecolare:357.16Ref: TM-T16850
1mg56,00€5mg119,00€10mg187,00€25mg376,00€50mg560,00€100mg800,00€500mg1.644,00€1mL*10mM (DMSO)131,00€Danirixin
CAS:<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Formula:C19H21ClFN3O4SPurezza:99.78% - >99.99%Colore e forma:SolidPeso molecolare:441.9ML 145
CAS:ML 145 is a selective antagonist of GPR35/CXCR8 (IC50/EC50 of 20.1 nM)Formula:C24H22N2O5S2Purezza:97.74%Colore e forma:SolidPeso molecolare:482.57Ref: TM-T12074
1mg50,00€5mg105,00€10mg158,00€25mg264,00€50mg430,00€100mg605,00€1mL*10mM (DMSO)115,00€ICT5040
CAS:ICT5040 is a CXCR4 antagonist.Formula:C10H8F3N3OSColore e forma:SolidPeso molecolare:275.25rac-NBI-74330
CAS:rac-NBI-74330 is an effective and selective CXCR3 antagonist.Formula:C32H27F4N5O3Purezza:99.6%Colore e forma:SolidPeso molecolare:605.58SCH 546738
CAS:SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.Formula:C23H31Cl2N7OPurezza:98.67%Colore e forma:SolidPeso molecolare:492.45PS372424
CAS:PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.Formula:C33H44N6O4Purezza:98%Colore e forma:SolidPeso molecolare:588.74AZ10397767
CAS:<p>AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.</p>Formula:C15H14ClFN4O2S2Colore e forma:SolidPeso molecolare:400.88AMD 3465
CAS:AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).Formula:C24H38N6Purezza:98%Colore e forma:SolidPeso molecolare:410.60GPR35 agonist 1
CAS:GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).Formula:C10H4BrN5O5Purezza:98%Colore e forma:SolidPeso molecolare:354.07SB02024
CAS:SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.Formula:C16H22F3N3O2Colore e forma:SolidPeso molecolare:345.36ACT-660602
CAS:ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.Formula:C20H20F6N8OSColore e forma:SolidPeso molecolare:534.48CXCR4 antagonist 5
CAS:CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.Formula:C21H30N6Colore e forma:SolidPeso molecolare:366.5CXCR3 Antagonist 6c
CAS:CXCR3 antagonist 6c blocks CXCR3 and inhibits Ca2+ movement and T-cell migration (IC50: 0.06 µM & 100 nM) with selectivity over 14 other GPCRs.Formula:C30H32Cl3N5O3Colore e forma:SolidPeso molecolare:616.97
