TLR

TLR7/8 agonist 1 is a TLR7/8 agonist which shows prominent immunostimulatory activities.

Loxoribine is a guanosine analog. Loxoribine is an orally bioavailable and selective Toll-like receptor (TLR) …

AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for …

RS09 2TFA is a TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion …

Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal …

CL264, a specific agonist of TLR7, is used for innate immune signals research.

PF-4878691 is an effective and selective Toll-like receptor 7 agonists modelled. It is used to …

Resiquimod is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying …

CU-CPT22 is the first probe for the complex between toll-like receptors TLR1 and TLR2. CU-CPT22 …

TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and …

CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).

3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is …

IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling. It inhibits MAPK and p65 …

Hydroxychloroquine sulfate inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic …

1V209 is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.

LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.

A natural, noncaloric sweetener with a potency 300 times more than that of regular sucrose. …

MD2-IN-1 is an inhibitor of Myeloid differentiation protein 2 (MD2) with a KD of 189 …

CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM). It inhibits …

Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.

BBIQ is a powerful vaccine adjuvant that enhances innate immune responses[1][2] and it is a …

Pam3CSK4 TFA is an agonist of toll-like receptor 1/2 (TLR1/2) (EC50 of 0.47 ng/mL for …

Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the …

MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.

CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It …

TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).

CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling …

E6446 dihydrochloride is a novel synthetic antagonist for nucleic acid-sensing TLRs; potently suppressed DNA stimulation …

Procyanidin B1, isolated from commonly eaten fruits, binds to the TLR4/MD-2 complex and has anti-inflammatory …

E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human …

Gardiquimod could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells. Gardiquimod is …

CU-CPT-8m is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)

Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R …

Leonurine (hydrochloride), a major alkaloid compound extracted from Leonurus japonicas Houtt. (Labiatae), is considered to …

GS-9620 is an effective and specific orally active agonist of Toll-like receptor 7.

Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist.

C29 is a novel inhibitor of TLR2/1 and TLR2/6 signaling induced by synthetic and bacterial …

Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), …

Hydroxychloroquine (HCQ) is an alkalinizing lysosomatropic drug that acts by inducing apoptosis of renal cancer …

CU CPT 4a is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). …

Poly (I:C) is a synthetic double-stranded RNA (dsRNA) analog and is an immunostimulant that acts …

TLR7-agonist-1 is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).

SM 324405 is an agonist of TLR7.

LPA1 antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist (IC50: 25 nM).

Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.

Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM). Enpatoran …