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TLR

TLR

I recettori Toll-like (TLR) sono una classe di proteine che svolgono un ruolo fondamentale nel sistema immunitario innato riconoscendo i pattern molecolari associati ai patogeni (PAMP) e iniziando risposte immunitarie. I TLR sono coinvolti nel rilevamento di un'ampia gamma di patogeni, tra cui batteri, virus e funghi, e sono essenziali per l'attivazione delle vie di segnalazione infiammatorie. La disregolazione della segnalazione dei TLR è associata a malattie infiammatorie croniche, disturbi autoimmuni e cancro. Presso CymitQuimica, offriamo una varietà di modulatori TLR di alta qualità per supportare la tua ricerca sull'immunità innata, l'infiammazione e le malattie infettive.

Trovati 76 prodotti di "TLR"

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  • IAXO-102

    CAS:
    IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling.
    Formula:C35H71NO5
    Purezza:98.17%
    Colore e forma:Solid
    Peso molecolare:585.94

    Ref: TM-T11598

    1mg
    87,00€
    2mg
    134,00€
    5mg
    250,00€
    10mg
    400,00€
    25mg
    655,00€
    50mg
    932,00€
    100mg
    1.283,00€
  • CU-CPT17e

    CAS:
    CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).
    Formula:C27H24N2O8
    Purezza:98.49%
    Colore e forma:Solid
    Peso molecolare:504.49

    Ref: TM-T10899

    1mg
    202,00€
    5mg
    419,00€
    10mg
    617,00€
    25mg
    938,00€
    50mg
    1.320,00€
    100mg
    1.776,00€
  • TLR7/8 agonist 3

    CAS:
    <p>TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.</p>
    Formula:C17H23N5O
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:313.4

    Ref: TM-T13167

    1mg
    64,00€
    5mg
    140,00€
    10mg
    226,00€
    25mg
    368,00€
    50mg
    509,00€
    100mg
    702,00€
    200mg
    944,00€
  • BMS-905

    CAS:
    BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members.
    Formula:C23H29N3
    Purezza:99.94%
    Colore e forma:Soild
    Peso molecolare:347.5

    Ref: TM-T60052

    1mg
    74,00€
    5mg
    170,00€
    10mg
    259,00€
    25mg
    429,00€
    50mg
    605,00€
    100mg
    815,00€
    500mg
    Prezzo su richiesta
  • CU-T12-9

    CAS:
    CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay).
    Formula:C17H13F3N4O2
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:362.31

    Ref: TM-T15017

    1mg
    52,00€
    5mg
    111,00€
    10mg
    169,00€
    25mg
    283,00€
    50mg
    432,00€
    100mg
    615,00€
    1mL*10mM (DMSO)
    124,00€
  • CU-CPT22

    CAS:
    CU-CPT22: first TLR1/2 complex probe, binds at TLR1/2 interface (IC50=0.58μM), inhibits Pam3CSK4 binding (Ki=0.41μM).
    Formula:C19H22O7
    Purezza:98.66% - 99.80%
    Colore e forma:Solid
    Peso molecolare:362.37

    Ref: TM-T15020

    1mg
    52,00€
    2mg
    70,00€
    5mg
    99,00€
    10mg
    168,00€
    25mg
    313,00€
    50mg
    469,00€
    100mg
    682,00€
    200mg
    938,00€
    1mL*10mM (DMSO)
    114,00€
  • ODN 4084-F

    CAS:
    ODN 4084-F, a class B ('broadly-active') inhibitory ODN, is a potent inhibitor of TLR9-induced B cells and macrophages.
    Colore e forma:Solid

    Ref: TM-T87057

    10mg
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  • L07-2

    CAS:
    L07-2 (Compound 6) is an active scaffold that includes a TLR7/8 agonist. It is suitable for the synthesis of immune-stimulating antibody conjugates (ISACs) used in cancer research.
    Formula:C56H83N15O14
    Colore e forma:Solid
    Peso molecolare:1190.35

    Ref: TM-T212382

    10mg
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  • Tilsotolimod sodium

    CAS:
    Tilsotolimod sodium, a synthetic Toll-like receptor 9 (TLR9) agonist, has shown antitumor activity in preclinical models.
    Formula:C223H262N74Na22O115P22S22
    Colore e forma:Solid
    Peso molecolare:7711.51

    Ref: TM-T87528

    10mg
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  • PVP-037.2

    CAS:
    PVP-037.2 is a TLR7/8 agonist that acts as an adjuvant to enhance vaccine-induced TH1 immune responses and boost the production of antigen-specific antibodies IgG1 and IgG2c.
    Formula:C23H20F3N5O
    Colore e forma:Soild
    Peso molecolare:439.43

    Ref: TM-T89354

    10mg
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    50mg
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  • Ezeprogind

    CAS:
    Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust
    Formula:C25H44N6
    Purezza:99.28%
    Colore e forma:Solid
    Peso molecolare:428.66

    Ref: TM-T40701

    1mg
    279,00€
    5mg
    685,00€
    10mg
    938,00€
    25mg
    1.444,00€
    50mg
    1.882,00€
    100mg
    2.622,00€
  • TLR7 agonist 17

    CAS:
    TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].
    Formula:C25H37N7O3
    Colore e forma:Solid
    Peso molecolare:483.61

    Ref: TM-T87535

    25mg
    2.225,00€
    50mg
    2.921,00€
    100mg
    3.921,00€
  • Pam3CSK4-Biotin

    CAS:
    Pam3CSK4-Biotin is a biotinylated derivative of Pam3CSK4, functioning as a Toll-like receptor 1/2 (TLR1/2) agonist.
    Formula:C103H192N14O17S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1962.85

    Ref: TM-TP1066

    100mg
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    500mg
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  • Pam2CSK4

    CAS:
    <p>TLR2/6 agonist; boosts TNF-α in human cells &amp; mouse B cell growth/activation.</p>
    Formula:C65H126N10O12S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1271.83

    Ref: TM-TP1962

    1mg
    818,00€
  • MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA


    MC-Val-Cit-PAB-Amide-TLR7 agonist 4 TFA is the trifluoroacetate form of MC-Val-Cit-PAB-Amide-TLR7 agonist 4,a HER2-TLR7 and HER2- TLR8 immune agonist complexes.
    Formula:C54H73F3N12O13
    Purezza:99.67%
    Colore e forma:Solid
    Peso molecolare:1155.22

    Ref: TM-T74468L

    1mg
    201,00€
    5mg
    497,00€
    10mg
    701,00€
    25mg
    1.094,00€
    50mg
    1.508,00€
    100mg
    1.931,00€
    200mg
    2.637,00€
  • RKH acetate


    RKH acetate offers protective effects against mortality and organ damage caused by sepsis. It can directly bind to Toll-like receptor 4 (TLR4) and inhibit TLR4 signaling in immune cells.
    Formula:C18H33N9O4·xC2H4O2

    Ref: TM-TP3509

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • CRX 527

    CAS:
    CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.
    Formula:C81H151N2O19P
    Colore e forma:Solid
    Peso molecolare:1488.04

    Ref: TM-T204958

    10mg
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    50mg
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  • MTvkPABC-P5 TFA


    MTvkPABC-P5d TFA, a TLR7 agonist, functions as an immune stimulant. It is applicable in the synthesis of immune-stimulating antibody conjugates (ISAC).
    Colore e forma:Odour Solid

    Ref: TM-T206783

    10mg
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    50mg
    Prezzo su richiesta
  • TLR7/8 agonist 12


    <p>TLR7/8 agonist 12 (compound 9) is a human TLR7/8 agonist with EC50 values of 11 nM for hTLR7 and 150 nM for hTLR8, indicating its potential for immune modulation.</p>
    Formula:C29H38N6O3
    Colore e forma:Solid
    Peso molecolare:518.65

    Ref: TM-T205162

    10mg
    Prezzo su richiesta
    50mg
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  • TLR7 agonist 24


    TLR7 agonist24 (Compound 21) is an agonist of TLR7 with an EC50 of 3.72 μM. When combined with Aluminum Hydroxide, it can be employed as a vaccine adjuvant to enhance the immune response to antigens from SARS-CoV-2 and hepatitis B.
    Colore e forma:Odour Solid

    Ref: TM-T89468

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • RKH


    PKH is a TLR4 antagonist, and it is a new tripeptide derived from Akkermansia muciniphila. PKH reduces inflammation-related cell activation and the overproduction of pro-inflammatory factors induced by sepsis.
    Formula:C18H33N9O4
    Peso molecolare:439.26555

    Ref: TM-TP3505

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • IPH33


    IPH33 is a human monoclonal antibody (mAb) targeting TLR3/CD283. It is useful for research in cancer and inflammation.
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-1735

    1mg
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    5mg
    Prezzo su richiesta
  • Tomaralimab

    CAS:
    <p>Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS).</p>
    Purezza:100% (SEC-HPLC) - > 95%
    Colore e forma:Liquid
    Peso molecolare:145.32 kDa

    Ref: TM-T76975

    1mg
    155,00€
    5mg
    376,00€
    10mg
    567,00€
    25mg
    887,00€
    50mg
    1.188,00€
  • CU-115

    CAS:
    <p>CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =&gt;50 µM for TLR8 and TLR7, respectively.</p>
    Formula:C21H11F7INO2
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:569.21

    Ref: TM-T9645

    1mg
    58,00€
    5mg
    144,00€
    10mg
    227,00€
    25mg
    393,00€
    50mg
    550,00€
    100mg
    753,00€
  • TLR8 agonist 8

    CAS:
    TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.
    Formula:C53H63N11O10
    Colore e forma:Solid
    Peso molecolare:1014.14

    Ref: TM-T88252

    10mg
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    50mg
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  • TLR8 agonist 7

    CAS:
    TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.
    Formula:C54H63N9O16
    Colore e forma:Solid
    Peso molecolare:1094.13

    Ref: TM-T88108

    10mg
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  • (R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2


    (R)-Thalidomide-pyrrolidine-C-piperidine-Ph-NH2 serves as the E3 ubiquitin ligase ligand and linker for PROTAC(R)-NX-2127, utilized in cancer research.
    Formula:C29H33N5O4
    Colore e forma:Solid
    Peso molecolare:515.6

    Ref: TM-T201702

    10mg
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    50mg
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  • Toll-like receptor modulator

    CAS:
    Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
    Formula:C15H13F5N2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:348.27

    Ref: TM-T13182

    2mg
    71,00€
  • TLR7 agonist 3

    CAS:
    <p>TLR7 agonist 3 is a Toll-like receptor 7 (TLR7) agonist that has anticancer activity and is used in the study of diseases of the immune system.</p>
    Formula:C18H24N4O
    Purezza:99.27%
    Colore e forma:Solid
    Peso molecolare:312.41

    Ref: TM-T38614

    1mg
    115,00€
    5mg
    274,00€
    10mg
    455,00€
    25mg
    748,00€
    50mg
    1.064,00€
    100mg
    1.415,00€
  • Neoseptin-3

    CAS:
    Neoseptin-3 is a novel small molecule agonist of mouse mTLR4/MD2 with EC50=18.5 μM that does not activate human TLR4/MD2.
    Formula:C29H34N2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:474.59

    Ref: TM-T16284

    1mg
    98,00€
  • Desethyl chloroquine diphosphate

    CAS:
    Desethyl chloroquine diphosphate is the active metabolite of Desethylchloroquine, an inhibitor of TLRs with antiplasmodial activity and inhibition of autophagy.
    Formula:C16H28ClN3O8P2
    Purezza:99.72%
    Colore e forma:Solid
    Peso molecolare:487.81

    Ref: TM-T11001L

    2mg
    284,00€
  • Pam3CSK4

    CAS:
    Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.
    Formula:C81H156N10O13S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1510.23

    Ref: TM-TP1068

    100mg
    Prezzo su richiesta
    500mg
    Prezzo su richiesta
  • Pam3CSK4 TFA (112208-00-1 free base)

    CAS:
    <p>Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.</p>
    Formula:C87H159F9N10O19S
    Purezza:96.4% - 99.01%
    Colore e forma:Solid
    Peso molecolare:1852.33

    Ref: TM-TP1067

    1mg
    127,00€
    5mg
    283,00€
    10mg
    477,00€
    25mg
    812,00€
    50mg
    Prezzo su richiesta
  • TLR7 agonist 2

    CAS:
    <p>TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).</p>
    Formula:C17H16N6O2
    Purezza:99.33%
    Colore e forma:Solid
    Peso molecolare:336.35

    Ref: TM-T4258

    1mg
    157,00€
    5mg
    396,00€
    10mg
    550,00€
    25mg
    929,00€
    50mg
    1.283,00€
    100mg
    1.776,00€
  • TLR7/8 agonist 1

    CAS:
    TLR7/8 agonist 1 is a toll-like receptor TLR7/TLR8 agonist with anticancer and antiviral activities and can be used to study immune-related diseases.
    Formula:C22H25N5
    Purezza:99.4%
    Colore e forma:Solid
    Peso molecolare:359.47

    Ref: TM-T71108

    1mg
    52,00€
    5mg
    115,00€
    10mg
    178,00€
    25mg
    378,00€
    50mg
    648,00€
    100mg
    1.074,00€
  • Telratolimod

    CAS:
    <p>Telratolimod (MEDI9197) is a toll-like receptors 7/8 agonist. It has an antitumor activity.</p>
    Formula:C36H59N5O2
    Purezza:98.61%
    Colore e forma:Solid
    Peso molecolare:593.89

    Ref: TM-T17032

    1mg
    172,00€
    2mg
    235,00€
    5mg
    354,00€
    10mg
    528,00€
    25mg
    852,00€
    50mg
    1.159,00€
    100mg
    1.568,00€
  • Enpatoran

    CAS:
    Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM).
    Formula:C16H15F3N4
    Purezza:97.08% - 99.38%
    Colore e forma:Solid
    Peso molecolare:320.31

    Ref: TM-T9570

    1mg
    119,00€
    5mg
    235,00€
    10mg
    354,00€
    25mg
    582,00€
    50mg
    825,00€
    100mg
    1.111,00€
    200mg
    1.491,00€
    1mL*10mM (DMSO)
    170,00€
  • Gardiquimod

    CAS:
    Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.
    Formula:C17H23N5O
    Purezza:98.02% - 99.68%
    Colore e forma:Solid
    Peso molecolare:313.4

    Ref: TM-T15371

    5mg
    48,00€
    10mg
    70,00€
    25mg
    144,00€
    50mg
    Prezzo su richiesta
    1mL*10mM (DMSO)
    52,00€
  • CU-CPT-8m

    CAS:
    CU-CPT-8m (TLR8-specific antagonist) is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM)
    Formula:C14H12N4O
    Purezza:99.00%
    Colore e forma:Solid
    Peso molecolare:252.27

    Ref: TM-T7347

    2mg
    38,00€
    5mg
    52,00€
    10mg
    85,00€
    25mg
    138,00€
    50mg
    210,00€
    100mg
    316,00€
    1mL*10mM (DMSO)
    71,00€
  • SM-324405

    CAS:
    SM-324405 is an agonist of TLR7.
    Formula:C19H23N5O4
    Purezza:97.83%
    Colore e forma:Solid
    Peso molecolare:385.42

    Ref: TM-T7860

    2mg
    35,00€
    5mg
    55,00€
    10mg
    88,00€
    25mg
    145,00€
    50mg
    226,00€
    100mg
    324,00€
    200mg
    452,00€
    1mL*10mM (DMSO)
    60,00€
  • CU-CPT9b

    CAS:
    CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).
    Formula:C16H13NO2
    Purezza:98.1%
    Colore e forma:Solid
    Peso molecolare:251.28

    Ref: TM-T7302

    1mg
    52,00€
    5mg
    97,00€
    10mg
    160,00€
    25mg
    259,00€
    50mg
    359,00€
    100mg
    532,00€
    200mg
    757,00€
    1mL*10mM (DMSO)
    111,00€
  • MD2-IN-1

    CAS:
    MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189  μM for the recombinant human MD2 (rhMD2).
    Formula:C20H22O6
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:358.39

    Ref: TM-T4231

    1mg
    59,00€
    5mg
    126,00€
    10mg
    187,00€
    25mg
    354,00€
    50mg
    533,00€
    100mg
    802,00€
    1mL*10mM (DMSO)
    139,00€
  • C29

    CAS:
    C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.
    Formula:C16H15NO4
    Purezza:96.34% - 97.37%
    Colore e forma:Solid
    Peso molecolare:285.29

    Ref: TM-T3502

    1mg
    51,00€
    5mg
    97,00€
    10mg
    180,00€
    25mg
    283,00€
    50mg
    432,00€
    100mg
    655,00€
    1mL*10mM (DMSO)
    150,00€
  • TLR3-IN-1

    CAS:
    TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.
    Formula:C18H13ClFNO3S
    Purezza:98.56%
    Colore e forma:Solid
    Peso molecolare:377.82

    Ref: TM-T22698

    1mg
    50,00€
    5mg
    108,00€
    10mg
    177,00€
    25mg
    378,00€
    50mg
    563,00€
    100mg
    802,00€
    200mg
    1.093,00€
    1mL*10mM (DMSO)
    119,00€
  • CU-CPT-9a

    CAS:
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-
    Formula:C17H15NO2
    Purezza:99.01%
    Colore e forma:Solid
    Peso molecolare:265.31

    Ref: TM-T7317

    1mg
    40,00€
    2mg
    52,00€
    5mg
    88,00€
    10mg
    126,00€
    25mg
    236,00€
    50mg
    432,00€
    100mg
    638,00€
    1mL*10mM (DMSO)
    87,00€
  • TLR7/8/9-IN-1

    CAS:
    TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
    Formula:C27H37N3O2
    Purezza:99.56%
    Colore e forma:Solid
    Peso molecolare:435.6

    Ref: TM-T39669

    1mg
    52,00€
    2mg
    73,00€
    5mg
    117,00€
    10mg
    188,00€
    25mg
    306,00€
    50mg
    449,00€
    100mg
    610,00€
    200mg
    872,00€
    1mL*10mM (DMSO)
    170,00€
  • TLR4-IN-C34

    CAS:
    TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis
    Formula:C17H27NO9
    Purezza:99.69%
    Colore e forma:Solid
    Peso molecolare:389.4

    Ref: TM-T8503

    2mg
    46,00€
    5mg
    66,00€
    10mg
    93,00€
    25mg
    131,00€
    50mg
    205,00€
    100mg
    303,00€
    1mL*10mM (DMSO)
    74,00€
  • Bropirimine

    CAS:
    Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.
    Formula:C10H8BrN3O
    Purezza:99.01%
    Colore e forma:Solid
    Peso molecolare:266.09

    Ref: TM-T5521

    10mg
    48,00€
    25mg
    77,00€
    50mg
    97,00€
    100mg
    143,00€
    200mg
    205,00€
    1mL*10mM (DMSO)
    35,00€
  • 1V209

    CAS:
    1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.
    Formula:C16H17N5O5
    Purezza:99.61%
    Colore e forma:Solid
    Peso molecolare:359.34

    Ref: TM-T8316

    5mg
    50,00€
    10mg
    85,00€
    25mg
    169,00€
    50mg
    238,00€
    100mg
    335,00€
    200mg
    477,00€
    1mL*10mM (DMSO)
    51,00€
  • TH1020

    CAS:
    TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.
    Formula:C23H15N7S2
    Purezza:99.23%
    Colore e forma:Solid
    Peso molecolare:453.54

    Ref: TM-T8727

    2mg
    47,00€
    5mg
    70,00€
    10mg
    96,00€
    25mg
    188,00€
    50mg
    354,00€
    100mg
    528,00€
  • Motolimod

    CAS:
    Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.
    Formula:C28H34N4O2
    Purezza:97.43% - 99.66%
    Colore e forma:Solid
    Peso molecolare:458.6

    Ref: TM-T6898

    1mg
    37,00€
    5mg
    80,00€
    10mg
    116,00€
    25mg
    226,00€
    50mg
    338,00€
    100mg
    482,00€
    1mL*10mM (DMSO)
    88,00€
  • TLR7/8 agonist 1 dihydrochloride

    CAS:
    TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.
    Formula:C22H27Cl2N5
    Purezza:98.33%
    Colore e forma:Solid
    Peso molecolare:432.39

    Ref: TM-T5561

    1mg
    57,00€
    5mg
    120,00€
    10mg
    187,00€
    25mg
    406,00€
    50mg
    630,00€
    100mg
    898,00€
    200mg
    1.216,00€
    1mL*10mM (DMSO)
    133,00€
  • Robinin

    CAS:
    Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.
    Formula:C33H40O19
    Purezza:98.78% - 99.13%
    Colore e forma:Solid
    Peso molecolare:740.66

    Ref: TM-T2S0265

    1mg
    74,00€
    5mg
    160,00€
    10mg
    230,00€
    25mg
    378,00€
    50mg
    Prezzo su richiesta
  • Paridiprubart

    CAS:
    Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.
    Purezza:95% - 96.9% (SDS-PAGE); 98.5% (SEC-HPLC)
    Colore e forma:Liquid

    Ref: TM-T74427

    1mg
    169,00€
    5mg
    408,00€
    10mg
    653,00€
    25mg
    1.010,00€
    50mg
    1.346,00€
  • AZD8848

    CAS:
    AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
    Formula:C29H43N7O5
    Colore e forma:Solid
    Peso molecolare:569.7

    Ref: TM-T10437

    25mg
    1.539,00€
    50mg
    2.005,00€
    100mg
    2.945,00€
  • TLR7 agonist 1

    CAS:
    TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
    Formula:C21H25N5O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:363.46

    Ref: TM-T13168

    25mg
    1.169,00€
    50mg
    1.529,00€
    100mg
    2.375,00€
  • CL264

    CAS:
    CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.
    Formula:C19H23N7O4
    Purezza:98.01%
    Colore e forma:Solid
    Peso molecolare:413.43

    Ref: TM-T10833

    1mg
    51,00€
    5mg
    116,00€
    10mg
    192,00€
    25mg
    304,00€
    50mg
    420,00€
    100mg
    560,00€
    200mg
    755,00€
    1mL*10mM (DMSO)
    128,00€
  • DSR-6434

    CAS:
    <p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>
    Formula:C19H28N8O2
    Purezza:99.78%
    Colore e forma:Solid
    Peso molecolare:400.48

    Ref: TM-T11108

    5mg
    49,00€
    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • AXC-715 trihydrochloride

    CAS:
    AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.
    Formula:C18H28Cl3N5
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:420.81

    Ref: TM-T72253

    1mg
    94,00€
    5mg
    208,00€
    10mg
    341,00€
    25mg
    553,00€
    50mg
    765,00€
    100mg
    1.026,00€
    200mg
    1.388,00€
  • AT791

    CAS:
    AT791 is an orally available TLR7 and TLR9 inhibitor, suppressing TLR7 and TLR9 signaling, used in autoimmune lupus research.
    Formula:C23H31N3O3
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:397.51

    Ref: TM-T61882

    1mg
    72,00€
    5mg
    156,00€
    10mg
    235,00€
    25mg
    378,00€
    50mg
    540,00€
    100mg
    747,00€
    200mg
    1.035,00€
    1mL*10mM (DMSO)
    167,00€
  • TLR7/8-IN-1

    CAS:
    <p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>
    Formula:C29H40N8O2
    Purezza:99.83%
    Colore e forma:Solid
    Peso molecolare:532.68

    Ref: TM-T38078

    1mg
    180,00€
    5mg
    455,00€
    10mg
    682,00€
    25mg
    1.159,00€
    50mg
    1.605,00€
    100mg
    2.157,00€
  • Rabeximod

    CAS:
    Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.
    Formula:C22H24ClN5O
    Purezza:99.99%
    Colore e forma:Solid
    Peso molecolare:409.91

    Ref: TM-T34249

    1mg
    107,00€
    5mg
    256,00€
    10mg
    364,00€
    25mg
    550,00€
  • BBIQ

    CAS:
    BBIQ is a powerful vaccine adjuvant that enhances innate immune responses and a potent and selectively toll-like receptor 7 (TLR7) agonist with an EC50 of  59.1
    Formula:C21H22N4
    Purezza:99.71%
    Colore e forma:Solid
    Peso molecolare:330.43

    Ref: TM-T14513

    25mg
    54,00€
    1mL*10mM (DMSO)
    34,00€
  • M62812

    CAS:
    TLR4 inhibitor blocks LPS-induced NF-κB (IC50=2.4μg/mL), cytokines in PBMCs/HUVECs, and extends life in septic shock mice.
    Formula:C13H13Cl2N3OS
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:330.23

    Ref: TM-T37292

    5mg
    50,00€
    10mg
    73,00€
    25mg
    142,00€
    50mg
    234,00€
    100mg
    340,00€
    1mL*10mM (DMSO)
    70,00€
  • SM360320

    CAS:
    <p>SM360320 (CL-087) is a selective TLR7 agonist that blocks HCV replication in hepatocytes and aids immunology research.</p>
    Formula:C15H17N5O3
    Purezza:99.13%
    Colore e forma:Solid
    Peso molecolare:315.33

    Ref: TM-T19675

    1mg
    116,00€
    5mg
    244,00€
    10mg
    364,00€
    25mg
    562,00€
    50mg
    780,00€
    100mg
    1.035,00€
    500mg
    2.100,00€
  • 1Z105

    CAS:
    1Z105, an orally active TLR4/MD2 ligand, facilitates dendritic cell maturation and antigen presentation, thereby preventing arthritis.
    Formula:C25H26N4O2S
    Peso molecolare:446.57

    Ref: TM-T200347

    25mg
    1.637,00€
    50mg
    Prezzo su richiesta
    100mg
    Prezzo su richiesta
  • TLR7 agonist 23

    CAS:
    TLR7 agonist23 (compound 12b) is a potent agonist of Toll-like receptor-7 (TLR7), with an EC50 value of 0.15 uM. It is suitable for research in immune diseases.
    Formula:C21H22N4O2
    Colore e forma:Solid
    Peso molecolare:362.42

    Ref: TM-T88779

    25mg
    1.637,00€
    50mg
    2.137,00€
    100mg
    2.745,00€
  • TLR9-IN-1

    CAS:
    TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.
    Formula:C23H31N7O
    Colore e forma:Solid
    Peso molecolare:421.54

    Ref: TM-T62254

    1mg
    236,00€
  • CU-CPD107

    CAS:
    CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.
    Formula:C16H21IN2O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:400.25

    Ref: TM-T35349

    1mg
    66,00€
    5mg
    135,00€
    10mg
    207,00€
    25mg
    378,00€
    50mg
    537,00€
    100mg
    753,00€
    200mg
    1.026,00€
  • ABR-238901

    CAS:
    ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products
    Formula:C11H9BrClN3O4S
    Purezza:98.63% - 98.71%
    Colore e forma:Solid
    Peso molecolare:394.63

    Ref: TM-T39115

    1mg
    123,00€
    5mg
    298,00€
    10mg
    472,00€
    25mg
    748,00€
    50mg
    1.026,00€
    100mg
    1.406,00€
    1mL*10mM (DMSO)
    328,00€
  • SARM1-IN-4

    CAS:
    SARM1-IN-4 (Compound 7) is an orally active SARM1 inhibitor that reduces plasma neurofilament light chain (NfL) levels in a mouse model following a 50 mg/kg oral dose. By inhibiting the NAD+ hydrolase activity of SARM1, it prevents programmed axon degeneration, making it useful for research in neurodegenerative and neurological diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Parkinson's disease, and peripheral neuropathy.
    Formula:C13H17F2N3O2
    Colore e forma:Solid
    Peso molecolare:285.29

    Ref: TM-T206825

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • SARM1-IN-5

    CAS:
    SARM1-IN-5 (compound 1-23-a) is an inhibitor of SARM1, useful for researching diseases related to axonal degeneration, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).
    Formula:C18H17FN6O
    Colore e forma:Solid
    Peso molecolare:352.37

    Ref: TM-T207193

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • TLR7 agonist 28

    CAS:
    TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.
    Formula:C26H25N9O7
    Colore e forma:Solid
    Peso molecolare:575.533

    Ref: TM-T204940

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • Creatine ethyl ester

    CAS:
    Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.
    Formula:C6H13N3O2
    Colore e forma:Solid
    Peso molecolare:159.186

    Ref: TM-T206807

    10mg
    Prezzo su richiesta
    50mg
    Prezzo su richiesta
  • LHC-165

    CAS:
    LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
    Formula:C29H32F2N3O7P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:603.55

    Ref: TM-T15751

    25mg
    2.727,00€
    50mg
    3.591,00€
    100mg
    4.940,00€
  • TLR7/8/9 antagonist 2

    CAS:
    <p>TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.</p>
    Formula:C23H31N7
    Purezza:98%
    Colore e forma:Soild
    Peso molecolare:405.54

    Ref: TM-T72035

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