TLR
I recettori Toll-like (TLR) sono una classe di proteine che svolgono un ruolo fondamentale nel sistema immunitario innato riconoscendo i pattern molecolari associati ai patogeni (PAMP) e iniziando risposte immunitarie. I TLR sono coinvolti nel rilevamento di un'ampia gamma di patogeni, tra cui batteri, virus e funghi, e sono essenziali per l'attivazione delle vie di segnalazione infiammatorie. La disregolazione della segnalazione dei TLR è associata a malattie infiammatorie croniche, disturbi autoimmuni e cancro. Presso CymitQuimica, offriamo una varietà di modulatori TLR di alta qualità per supportare la tua ricerca sull'immunità innata, l'infiammazione e le malattie infettive.
Trovati 76 prodotti di "TLR"
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TLR3-IN-1
CAS:TLR3-IN-1 (CU CPT 4a) is a selective TLR3 inhibitor. It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the TNF-α and IL-1β.Formula:C18H13ClFNO3SPurezza:98.56%Colore e forma:SolidPeso molecolare:377.82Ref: TM-T22698
1mg50,00€5mg108,00€10mg177,00€25mg373,00€50mg532,00€100mg747,00€200mg1.093,00€1mL*10mM (DMSO)119,00€CU-CPT-9a
CAS:CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM), that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells-Formula:C17H15NO2Purezza:99.01%Colore e forma:SolidPeso molecolare:265.31Ref: TM-T7317
1mg40,00€2mg52,00€5mg88,00€10mg126,00€25mg236,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)87,00€TLR7/8/9-IN-1
CAS:TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.Formula:C27H37N3O2Purezza:99.56%Colore e forma:SolidPeso molecolare:435.6Ref: TM-T39669
1mg52,00€2mg73,00€5mg117,00€10mg188,00€25mg306,00€50mg449,00€100mg610,00€200mg872,00€1mL*10mM (DMSO)170,00€Pam3CSK4 TFA (112208-00-1 free base)
CAS:<p>Pam3CSK4 TFA (Pam3Cys-Ser-(Lys)4 TFA) is a Toll-like receptor 1/2 agonist with EC50 of 0.47 ng/mL for human TLR1/2.Cost-effective and quality-assured.</p>Formula:C87H159F9N10O19SPurezza:96.4% - 99.01%Colore e forma:SolidPeso molecolare:1852.33TLR4-IN-C34
CAS:TLR4-IN-C34 is an inhibitor of TLR4, and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitisFormula:C17H27NO9Purezza:99.69%Colore e forma:SolidPeso molecolare:389.4Bropirimine
CAS:Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.Formula:C10H8BrN3OPurezza:99.01%Colore e forma:SolidPeso molecolare:266.091V209
CAS:1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects.Formula:C16H17N5O5Purezza:99.61%Colore e forma:SolidPeso molecolare:359.34TH1020
CAS:TH1020 is a novel Inhibitor of Toll-Like Receptor 5 (TLR5)/Flagellin Complex with promising activity (IC50 =0.85±0.12 μm) and specificity.Formula:C23H15N7S2Purezza:99.23%Colore e forma:SolidPeso molecolare:453.54Motolimod
CAS:Motolimod (VTX-378) (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7.Formula:C28H34N4O2Purezza:97.43% - 99.66%Colore e forma:SolidPeso molecolare:458.6TLR7/8 agonist 1 dihydrochloride
CAS:TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Formula:C22H27Cl2N5Purezza:98.33%Colore e forma:SolidPeso molecolare:432.39Ref: TM-T5561
1mg57,00€5mg120,00€10mg187,00€25mg406,00€50mg630,00€100mg898,00€200mg1.216,00€1mL*10mM (DMSO)133,00€Robinin
CAS:Robinin: a kaempferol-derived flavone glycoside with antibacterial, diuretic traits; minimal effect on Colo 320 MDR1/LRP resistance; detected in MCF-7 cells.Formula:C33H40O19Purezza:98.78% - 99.13%Colore e forma:SolidPeso molecolare:740.66MD2-IN-1
CAS:MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).Formula:C20H22O6Purezza:99.87%Colore e forma:SolidPeso molecolare:358.39CU-CPT9b
CAS:CU-CPT9b (TLR8-specific antagonist 1) is an antagonist of toll-like receptor 8 (TLR8; Kd = 21 nM).Formula:C16H13NO2Purezza:98.1%Colore e forma:SolidPeso molecolare:251.28Ref: TM-T7302
1mg52,00€5mg97,00€10mg160,00€25mg259,00€50mg359,00€100mg532,00€200mg757,00€1mL*10mM (DMSO)111,00€Paridiprubart
CAS:Paridiprubart (NI-0101) is a humanised monoclonal antibody targeting TLR4, ameliorative effects in COVID-19 patients with ARDS and rheumatoid arthritis.Purezza:95% - 96.9% (SDS-PAGE); 98.5% (SEC-HPLC)Colore e forma:LiquidDSR-6434
CAS:<p>DSR-6434 is a selective agonist of TLR7 with antitumor effect. DSR-6434 exhibits EC50s of 7.2 nM and 4.6 nM for human and mouse.</p>Formula:C19H28N8O2Purezza:99.78%Colore e forma:SolidPeso molecolare:400.48AZD8848
CAS:AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.Formula:C29H43N7O5Colore e forma:SolidPeso molecolare:569.7AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Formula:C18H28Cl3N5Purezza:99.87%Colore e forma:SolidPeso molecolare:420.81CL264
CAS:CL264, a selective agonist of TLR7, can be used in studies about innate immune signals.Formula:C19H23N7O4Purezza:98.01%Colore e forma:SolidPeso molecolare:413.43Ref: TM-T10833
1mg51,00€5mg116,00€10mg192,00€25mg304,00€50mg420,00€100mg560,00€200mg755,00€1mL*10mM (DMSO)128,00€TLR7 agonist 1
CAS:TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).Formula:C21H25N5OPurezza:98%Colore e forma:SolidPeso molecolare:363.46TLR7/8-IN-1
CAS:<p>TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.</p>Formula:C29H40N8O2Purezza:99.83%Colore e forma:SolidPeso molecolare:532.68
