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MALT

MALT

Il tessuto linfoide associato alla mucosa (MALT) è un componente essenziale del sistema immunitario che protegge le superfici mucose dai patogeni. Il MALT comprende strutture come le tonsille, le placche di Peyer e l'appendice, che sono coinvolte nell'inizio delle risposte immunitarie agli antigeni incontrati sulle superfici mucose. La ricerca sul MALT è fondamentale per comprendere i meccanismi dell'immunità mucosale e per lo sviluppo di vaccini e trattamenti per le infezioni mucosali. Presso CymitQuimica, offriamo una gamma di reagenti e strumenti per supportare la tua ricerca in immunologia mucosale, infiammazione e malattie infettive.

Trovati 25 prodotti di "MALT"

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  • MLT-231


    <p>MLT-231: potent MALT1 Inhibitor, IC50=9 nM; blocks BCL10 cleavage, IC50=160 nM; exhibits antitumor efficacy in mouse ABC-DLBCL model.</p>
    Colore e forma:Solid
  • MALT1-IN-14

    CAS:
    MALT1-IN-14 (comp 2) acts as an inhibitor of MALT1, boasting an IC50 value of 0.081 μM.
    Formula:C26H25ClF5N5O3S
    Peso molecolare:618.02
  • MLT-985

    CAS:
    MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC 50 value of 3 nM.
    Formula:C17H15Cl2N9O2
    Colore e forma:Solid
    Peso molecolare:448.27
  • Cladribine

    CAS:
    Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.
    Formula:C10H12ClN5O3
    Purezza:99.58% - >99.99%
    Colore e forma:White Crystalline Solid
    Peso molecolare:285.69
  • MLT-943

    CAS:
    MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. [1].
    Formula:C16H14ClF3N6O2
    Purezza:99.72% - 99.82%
    Colore e forma:Solid
    Peso molecolare:414.77
  • MALT1 inhibitor MI-2

    CAS:
    <p>MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.</p>
    Formula:C19H17Cl3N4O3
    Purezza:98% - 99.87%
    Colore e forma:Solid
    Peso molecolare:455.72
  • MLT-748

    CAS:
    MLT-748 is an effective, selective, and allosteric MALT1 inhibitor. It binds MALT1 in the allosteric Trp580 pocket (IC50: 5 nM).
    Formula:C19H19Cl2N9O3
    Purezza:99.62%
    Colore e forma:Solid
    Peso molecolare:492.32
  • (R)-MALT1-IN-3

    CAS:
    (R)-MALT1-IN-3 (121) inhibits MALT1 protease (IC50: 20 nM) and IL6/IL10 in OCI-LY3 (IC50: 60/40 nM).
    Formula:C21H19F3N8O2
    Colore e forma:Solid
    Peso molecolare:472.42
  • MALT1-IN-8

    CAS:
    MALT1-IN-8: potent MALT1 inhibitor, IC50=2 nM; hinders OCI-LY3 cells, IC50=1.16 μM; anticancer, from patent WO2018165385A1.
    Formula:C20H15Cl2N7O
    Colore e forma:Solid
    Peso molecolare:440.29
  • MALT1-IN-3

    CAS:
    MALT1-IN-3 is a potent inhibitor of MALT1 protease (IC50: 0.06 μM) with IC50 values of 0.14 and 0.13 μM for human IL6 and IL10, respectively, in OCI-LY3 cells.
    Formula:C21H19F3N8O2
    Colore e forma:Solid
    Peso molecolare:472.42
  • Z-VRPR-FMK

    CAS:
    Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.
    Formula:C31H49FN10O6
    Colore e forma:Solid
    Peso molecolare:676.78
  • MLT-747

    CAS:
    MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).
    Formula:C20H21Cl2N7O3
    Colore e forma:Solid
    Peso molecolare:478.33
  • (R)-MLT-985

    CAS:
    (R)-MLT-985 (compound 11) is a MALT1 protease inhibitor with IC50 of 3 nM, also blocking IL-2 in Jurkat cells and ABC-DLBCL cell growth.
    Formula:C17H15Cl2N9O2
    Colore e forma:Solid
    Peso molecolare:448.27
  • (R)-MALT1-IN-7

    CAS:
    (R)-MALT1-IN-7 (compound 142a) is a potent inhibitor of MALT1 protease and has potential for cancer research.
    Formula:C19H17F3N8O2S
    Colore e forma:Solid
    Peso molecolare:478.45
  • MALT1-IN-7

    CAS:
    MALT1-IN-7 (compound 142b) is a potent inhibitor of MALT1 protease with potential for cancer research.
    Formula:C19H17F3N8O2S
    Colore e forma:Solid
    Peso molecolare:478.45
  • MALT1-IN-9

    CAS:
    MALT1-IN-9: potent MALT1 protease inhibitor, IC50 <500 nM in Raji cells, significant anticancer effects.
    Formula:C16H12ClF3N6O
    Colore e forma:Solid
    Peso molecolare:396.75
  • MALT1-IN-6

    CAS:
    MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.
    Formula:C18H12Cl2F3N9O
    Colore e forma:Solid
    Peso molecolare:498.25
  • NVS-MALT1

    CAS:
    <p>NVS-MALT1 is an allosteric inhibitor of MALT1 [1].</p>
    Formula:C24H27ClF3N5O4S
    Colore e forma:Solid
    Peso molecolare:574.02
  • JNJ-67856633

    CAS:
    <p>JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .</p>
    Formula:C20H11F6N5O2
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:467.32
  • MALT1-IN-5

    CAS:
    MALT1-IN-5 is a potent inhibitor of the MALT1 protease and can be used in cancer research.
    Formula:C17H17ClF2N6O3
    Colore e forma:Solid
    Peso molecolare:426.80