Ricettore IL
I recettori dell'interleuchina (recettori IL) sono un gruppo di recettori che si legano alle interleuchine, una famiglia di citochine che svolgono ruoli essenziali nella regolazione del sistema immunitario, nell'infiammazione e nell'ematopoiesi. La disregolazione della segnalazione delle interleuchine è associata a varie malattie infiammatorie e autoimmuni, rendendo i recettori IL bersagli critici per l'intervento terapeutico. Gli antagonisti dei recettori IL sono studiati per il trattamento di condizioni come l'artrite reumatoide, la psoriasi e le malattie infiammatorie intestinali. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori IL di alta qualità per supportare la tua ricerca sulla segnalazione delle citochine, sull'immunologia e sulla terapia delle malattie infiammatorie.
Trovati 109 prodotti di "Ricettore IL"
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Vobarilizumab
CAS:Vobarilizumab (ALX-0061) is a humanized specific antibody targeting IL-6R and ALB, used in research on autoimmune diseases like rheumatoid arthritis.Purezza:>95%Colore e forma:LiquidMirikizumab
CAS:Mirikizumab (LY3074828) is a humanized antibody targeting the p19 subunit of interleukin-23 (IL-23).Purezza:98.41% (SEC-HPLC) - 98.41% (SEC-HPLC)Colore e forma:LiquidEnokizumab
CAS:<p>Enokizumab (MEDI-528) is a monoclonal antibody against interleukin IL-9. Enokizumab can be used to study asthma.</p>Purezza:SDS-PAGE:95% SEC-HPLC:99.23%Colore e forma:LiquidPeso molecolare:145.98 kDaPerakizumab
CAS:<p>Perakizumab (RG4934) is a humanized monoclonal antibody targeting IL-17A, used in the study of psoriatic arthritis and other autoimmune diseases.</p>Purezza:95.28% (SEC-HPLC) - 99.66% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.4 (kDa)Imsidolimab
CAS:<p>Imsidolimab (ANB 019) is a humanized anti-IL-36R monoclonal antibody that inhibits IL-36 signaling and can be used to study systemic pustular psoriasis.</p>Purezza:99.1% (SDS-PAGE); 96.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.7% (SEC-HPLC)Colore e forma:LiquidBRD6989
CAS:BRD6989, a cortistatin A analog, inhibits CDK8/19, enhances IL-10, and binds CDK8 with a 200 nM IC50.Formula:C16H16N4Purezza:99.43%Colore e forma:SolidPeso molecolare:264.33Brodalumab
CAS:<p>Brodalumab (AMG 827), a human IgG2 monoclonal antibody, inhibits IL-17R, treating psoriasis.</p>Purezza:98.3%Colore e forma:LiquidPeso molecolare:144.06 kDaLevilimab
CAS:<p>Levilimab (BCD-089) is a fully humanized human monoclonal antibody targeting membrane-bound and soluble IL-6 R for the study of rheumatoid arthritis.</p>Purezza:97.8% (SDS-PAGE); 97.3% (SEC-HPLC) - 97.8% (SDS-PAGE); 97.3% (SEC-HPLC)Colore e forma:LiquidIL-15-IN-1
CAS:IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM).Formula:C30H36N6O4SPurezza:99.16%Colore e forma:SolidPeso molecolare:576.712-Benzothiazolamine
CAS:2-ABT: nitrogen-rich heterocycle used in drug synthesis, inhibits P450, with anti-inflammatory, anticonvulsant, anticancer properties.Formula:C7H6N2SPurezza:99.09% - 99.3%Colore e forma:Plates From Water Physical Description Odorless Gray To White Powder (Ntp 1992)Peso molecolare:150.2Olamkicept
CAS:Olamkicept (FE-301) is a soluble gp130-Fc-fusion protein that inhibits interleukin 6 (IL-6) trans signaling.Purezza:98.2% (SDS-PAGE); 98.8% (SEC-HPLC) - 99.3% (SDS-PAGE); 97.6% (SEC-HPLC)Colore e forma:LiquidSarilumab
CAS:Sarilumab: Potent IL-6 blocker, human antibody, reduces inflammation, treats rheumatoid arthritis.Purezza:97.4%Colore e forma:LiquidPeso molecolare:144.12 kDaVunakizumab
CAS:<p>Vunakizumab is a humanized IgGκ monoclonal antibody targeting IL-17A, often linked to interleukin 22 to form Vunakizumab-IL22.</p>Purezza:95%Colore e forma:LiquidYQ128
CAS:YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity.Formula:C27H29ClN2O4S2Purezza:99.89%Colore e forma:SolidPeso molecolare:545.11PF-07038124 HCl
CAS:PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFNγ, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.Formula:C18H23BClNO4Purezza:97.34% - 99.13%Colore e forma:SoildPeso molecolare:363.64Ordesekimab
CAS:Ordesekimab (AMG 714) is a human anti-IL-15 IgG1 κ monoclonal antibody for studying NRCD.Purezza:> 95%Colore e forma:LiquidPeso molecolare:145.12 kDaDupilumab
CAS:Dupilumab (REGN-668) is a systemic immunomodulator for AD.Purezza:95.00% - >99.2%Colore e forma:LiquidSiltuximab
CAS:<p>Siltuximab（CNTO-328） is a monoclonal antibody with anti-tumor activity targeting IL-6 for the study of giant lymph node hyperplasia (MCD) and COVID-19.</p>Purezza:100% (SEC-HPLC) - > 95%Colore e forma:LiquidPeso molecolare:144.98 kDaIxekizumab
CAS:Ixekizumab: IgG4 antibody, neutralizes IL-17A (<3 pM), treats severe plaque psoriasis & arthritis.Purezza:98.86% (SEC-HPLC) - > 99.3% (SDS-PAGE); 95.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:146.2 kDaAbrezekimab
CAS:Abrezekimab (VR 942), a humanized antibody, blocks IL-13/IL-13Rα1, for asthma/lung disease study.Purezza:98.34% (SEC-HPLC) - 98.34% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:48.1 kDaBriakinumab
CAS:Briakinumab (ABT-874) is a monoclonal antibody targeting IL-12, used in the research of psoriasis multiple sclerosis.Purezza:>95%Colore e forma:LiquidElsilimomab
CAS:Elsilimomab (B-E8) is a monoclonal antibody targeting IL-6, inhibiting the induction of bone marrow stromal cell senescence by dnmt3a mutation clones.Purezza:>95%Colore e forma:LiquidXeligekimab
CAS:Xeligekimab (GR 1501) is a fully humanized monoclonal antibody that neutralizes IL-17A and has anti-inflammatory activity for the study of plaque psoriasis.Purezza:95%Colore e forma:LiquidRisankizumab
CAS:Risankizumab (BI 655066) is a monoclonal antibody for psoriasis, targeting IL-23, with high affinity (Kd <10 pM) and an IC50 of 2 pM.Purezza:SDS-PAGE:95.3%;SEC-HPLC:98.3%Colore e forma:LiquidPeso molecolare:145.85 kDaTildrakizumab
CAS:<p>Tildrakizumab (SCH 900222) is a humanized antibody against IL-23, with a 136 pM Kd, used for psoriasis research.</p>Purezza:> 95%Colore e forma:LiquidPeso molecolare:144.44 kDaOlokizumab
CAS:Revdofilimab (ABBV-368) is a human IgG monoclonal antibody targeting OX 40 with potential anticancer activity.Purezza:99% (SDS-PAGE); 98.3% (SEC-HPLC) - 99% (SDS-PAGE); 98.3% (SEC-HPLC)Colore e forma:LiquidBermekimab
CAS:Bermekimab (MABp1), an anti-interleukin-1α (IL-1α) monoclonal antibody.Bermekimab has potential anti-inflammatory activity to prevent skin inflammation.Colore e forma:LiquidPeso molecolare:145.45 kDaSpesolimab
CAS:Spesolimab (BI 655130) is an antibody targeting IL-36 receptor, key in immunity, for systemic pustular psoriasis and dermatitis studies.Purezza:> 95%Colore e forma:LiquidPeso molecolare:150 kDaNidanilimab
CAS:<p>Nidanilimab (CAN04) is an IL1RAP antibody with 1.10 pM affinity and antitumor effects on NSCLC and PDAC.</p>Purezza:> 95%Colore e forma:SoildPeso molecolare:150 kDaStapokibart
CAS:<p>Stapokibart (CM310) is a humanized monoclonal antibody targeting IL-4Rα, blocking IL-4Rα-mediated signaling. It is used in studies of atopic dermatitis.</p>Purezza:96.09% (SEC-HPLC) - 96.09% (SEC-HPLC)Colore e forma:LiquidMacrophage-activating lipopeptide 2 TFA
Macrophage-activating lipopeptide 2 TFA (MALP-2 TFA) is a diacylglycerol lipopeptide and TLR-2/TLR-6 agonist activates immune cell responses macrophages,Formula:C99H167N19O30S·xC2HF3O2Purezza:97.56%Colore e forma:SolidPeso molecolare:2135.56 (free base)CNTO 607
<p>CNTO 607 (Anti-IL-13 Antibody) is a humanized antibody targeting IL-13, useful for studying inflammation.</p>Purezza:98% (SDS-PAGE); 98.3% (SEC-HPLC) - 98% (SDS-PAGE); 98.3% (SEC-HPLC)Colore e forma:Odour LiquidPascolizumab
CAS:<p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>Purezza:> 95%Colore e forma:LiquidPeso molecolare:147.18 kDaReslizumab
CAS:Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG) 4 κ monoclonal antibody, thereby reducing eosinophil production and survival.Purezza:98.1% (SDS-PAGE); 98.6% (SEC-HPLC) - 98.1% (SDS-PAGE); 98.6% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:N/ATemtokibart
CAS:<p>Temtokibart is a humanized monoclonal antibody targeting IL22RA1, used in autoimmune and inflammatory disease research.</p>Colore e forma:LiquidPeso molecolare:145.5Daclizumab
CAS:<p>Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.</p>Purezza:SDS-PAGE:95% SEC-HPLC:99.99%Colore e forma:LiquidPeso molecolare:144.12 kDaPF-06342674
<p>PF-06342674 is a humanized monoclonal antibody targeting the IL-7 receptor-α, with immunoregulatory activity, used in Type 1 diabetes research.</p>Colore e forma:LiquidPeso molecolare:145.5kDaY13g dihydrochloride
<p>Y13g dihydrochloride is a potent inhibitor of interleukin 6 (IL-6) and acetylcholinesterase (AChE) (both targets of Alzheimer's disease (AD) progression are</p>Formula:C16H25ClN2O4Purezza:97.81%Colore e forma:SoildPeso molecolare:344.83Guselkumab
CAS:Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit.Purezza:SDS-PAGE:95% SEC-HPLC:98.97%Colore e forma:LiquidPeso molecolare:144.8 kDaMepolizumab
CAS:Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5.Purezza:98% - 98%Colore e forma:LiquidDectrekumab
CAS:<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Purezza:96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Colore e forma:LiquidTriphenyl phosphate
CAS:Triphenyl phosphate is an flame retardant and endocrine disruptor that activates MAO-A/ROS/NF-κB pathways, disrupting placental tryptophan metabolism.Formula:C18H15O4PPurezza:99.94%Peso molecolare:326.288ABzOH
CAS:<p>2-(Cyclopropylethynyl)benzoic acid: NSAID-like, anti-inflammatory, anti-tumor, hinders cytokines and various cancers.</p>Formula:C12H10O2Purezza:99.43%Colore e forma:SolidPeso molecolare:186.21Torudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Purezza:95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Colore e forma:Odour LiquidCanakinumab
CAS:<p>Canakinumab: Human IL-1β antibody, anti-inflammatory, treats gout & coronary disease, IC50 of 43.6 pM (human), 40.8 pM (monkey).</p>Purezza:98.8%Colore e forma:LiquidPeso molecolare:145.18 kDaMyD88-IN-1
CAS:<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formula:C23H24N6O7SPurezza:>99.99%Colore e forma:SoildPeso molecolare:528.54Anti-inflammatory agent 42
CAS:Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.Formula:C20H12N2OSPurezza:99.47%Colore e forma:SolidPeso molecolare:328.39Nosantine racemate
CAS:Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).Formula:C14H22N4O2Purezza:98%Colore e forma:SolidPeso molecolare:278.35Ziltivekimab
CAS:<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Purezza:95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Colore e forma:SoildIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Formula:C33H41FN6O4Purezza:99.46%Colore e forma:SolidPeso molecolare:604.71
