Ricettore IL
I recettori dell'interleuchina (recettori IL) sono un gruppo di recettori che si legano alle interleuchine, una famiglia di citochine che svolgono ruoli essenziali nella regolazione del sistema immunitario, nell'infiammazione e nell'ematopoiesi. La disregolazione della segnalazione delle interleuchine è associata a varie malattie infiammatorie e autoimmuni, rendendo i recettori IL bersagli critici per l'intervento terapeutico. Gli antagonisti dei recettori IL sono studiati per il trattamento di condizioni come l'artrite reumatoide, la psoriasi e le malattie infiammatorie intestinali. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori IL di alta qualità per supportare la tua ricerca sulla segnalazione delle citochine, sull'immunologia e sulla terapia delle malattie infiammatorie.
Trovati 110 prodotti di "Ricettore IL"
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Anti-Human IL-17A
CAS:Anti-Human IL-17A (Secukinumab H chain) is a human monoclonal antibody targeting IL-17A, offering high affinity and low immunogenicity for psoriasis.Purezza:98%Colore e forma:LiquidPeso molecolare:151 kDaIL-17A antagonist 1
CAS:IL-17A antagonist 1 is an IL-17A antagonist for the study of interleukin-related inflammatory and immune diseases.Formula:C33H41FN6O4Purezza:99.46%Colore e forma:SolidPeso molecolare:604.71Anakinra
CAS:Anakinra (Raleukin) is an antagonist of recombinant, nonglycosylated human IL-1R. It is the first biological agent to block the pro-inflammatory effects.Formula:C759H1186N208O232S10Purezza:95% - ≥95%Colore e forma:SolidPeso molecolare:17257.6Ossirene
CAS:Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Formula:C2H4Cl3O2Te·H4NPurezza:≥98%Colore e forma:SolidPeso molecolare:312.05Ref: TM-T6761
2mg42,00€5mg62,00€10mg87,00€25mg145,00€50mg208,00€100mg309,00€200mg460,00€1mL*10mM (DMSO)70,00€IL-17A inhibitor 1
CAS:<p>IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.</p>Formula:C24H27F5N8O4Purezza:99.37% - 99.37%Colore e forma:SolidPeso molecolare:586.51Apilimod 2HCl
CAS:Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Formula:C23H28Cl2N6O2Purezza:98.41%Colore e forma:SolidPeso molecolare:491.41GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Formula:C20H20N6OPurezza:99.52%Colore e forma:SolidPeso molecolare:360.41VGX-1027
CAS:VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Formula:C11H11NO3Purezza:99.54% - 99.86%Colore e forma:SolidPeso molecolare:205.21Apilimod
CAS:<p>Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.</p>Formula:C23H26N6O2Purezza:99.38% - 99.89%Colore e forma:SolidPeso molecolare:418.49Esonarimod
CAS:Esonarimod (KE-298) is an antirheumatic drug.Formula:C14H16O4SPurezza:97.44%Colore e forma:SolidPeso molecolare:280.34Secukinumab
CAS:Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for thePurezza:97.4% (SDS-PAGE); 98.3% (SEC-HPLC) - 99.10%Colore e forma:LiquidPeso molecolare:147.93 kDaSuplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Formula:C23H33NO7S2Purezza:99.34% - 99.65%Colore e forma:White Or Off-White CrystalsPeso molecolare:499.64RO2959 Hydrochloride
CAS:RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.Formula:C21H20ClF2N5OSPurezza:99.24%Colore e forma:SolidPeso molecolare:463.93GSK717
CAS:<p>GSK717: potent, selective NOD2 inhibitor; disrupts NOD2/TLR2 synergy; no effect on NOD1, TNFR1, TLR2.</p>Formula:C28H28N4O2Purezza:97.34% - 99.01%Colore e forma:SolidPeso molecolare:452.55Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Formula:C25H34N6O8S2Purezza:99.51% - ≥95%Colore e forma:SolidPeso molecolare:610.7CP 424174
CAS:CP 424174 blocks IL-1β processing (IC50: 210 nM), halts mature IL-1β formation, limits NLRP3, and is effective orally in vivo.Formula:C22H29ClN2O4SPurezza:>99.99%Colore e forma:SolidPeso molecolare:452.99YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Formula:C22H21N3O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:359.42Ref: TM-T3133
1mg35,00€2mg47,00€5mg69,00€10mg88,00€25mg160,00€50mg283,00€100mg399,00€1mL*10mM (DMSO)74,00€Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Formula:CH10Cl2Na2O10P2Purezza:98%Colore e forma:SolidPeso molecolare:360.92Sirukumab
CAS:Sirukumab (CNTO-136) is a humanized monoclonal antibody binding to IL-6, inhibiting IL-6-mediated signaling and transcription activator activation.Purezza:>95%Colore e forma:LiquidPeso molecolare:144.6 (kDa)Satralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Purezza:95%Colore e forma:LiquidBrazikumab
CAS:Brazikumab (AMG 139) is a humanized antibody targeting IL-23 by binding to the P19 subunit, a selective IL-23p19 antagonist.Purezza:98% (SDS-PAGE); 97.7% (SEC-HPLC) - 98% (SDS-PAGE); 97.7% (SEC-HPLC)Colore e forma:LiquidPicankibart
CAS:Picankibart (IBI112) is a human recombinant monoclonal antibody targeting IL-23p19, indicated for psoriasis treatment.Purezza:95% - 97.0% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:LiquidBempikibart
CAS:Bempikibart (ADX-914) is a fully humanised monoclonal antibody targeting IL-7Rα, inhibiting IL-17 and TSLP (Thymic stromal lymphopoietin), inflammation.Purezza:95% - 98.9% (SDS-PAGE); 97.4% (SEC-HPLC)Colore e forma:LiquidAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPurezza:99% - 99%Colore e forma:Odour LiquidSapelizumab
Sapelizumab is a humanised antibody targeting IL-6Ra/CD126, huIgG2-type heavy chains and huκ-type light chains, IL-6 antagonist NMOSD.Peso molecolare:~150 kDaLebrikizumab
CAS:Lebrikizumab is a humanised monoclonal antibody that targets and inhibits interleukin 13 (IL-13), suppressing Th2 inflammation.asthma and atopic dermatitis.Purezza:95%Colore e forma:LiquidAnrukinzumab
CAS:Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.Purezza:95%Colore e forma:LiquidPeso molecolare:145.38 kDaAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Purezza:95%Colore e forma:LiquidPeso molecolare:146.07 kDaGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Purezza:95%Colore e forma:LiquidPeso molecolare:144.93 kDaEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Purezza:95%Colore e forma:LiquidZiralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Purezza:95%Colore e forma:LiquidRademikibart
CAS:Rademikibart (CBP-201) is a human monoclonal antibody selective for IL-4Rα, exhibiting strong affinity with a KD of 20.7 pM for human IL-4Rα epitopes, withoutPurezza:95%Colore e forma:LiquidPeso molecolare:143.54 kDaGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Purezza:95%Colore e forma:LiquidBimekizumab
CAS:Bimekizumab is a humanised monoclonal antibody targeting IL17A/IL17F, blocking inflammation-driven osteoblast differentiation.Purezza:>99.99%Colore e forma:LiquidInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Purezza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Colore e forma:LiquidManfidokimab
CAS:Manfidokimab is an anti-IL-4Rα mAb that blocks IL-4/IL-13 signaling, in trials for atopic dermatitis.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDaCasdozokitug
CAS:Casdozokitug is a human IgG1κ anti-IL-27 antibody that blocks immunosuppressive activity, relevant in tumor immunology and immune checkpoint therapy research.Purezza:95% - 95.1% (SDS-PAGE); 97.2% (SEC-HPLC)Colore e forma:LiquidTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Purezza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:148.83 kDaLusvertikimab
CAS:Lusvertikimab (OSE-127) is a humanized anti-IL7R antibody with anti-leukemic efficacy and can be used to study leukemia.Purezza:95% - 98.4% (SDS-PAGE); 99% (SEC-HPLC)Colore e forma:LiquidD228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Formula:C22H28O12Purezza:99.91%Colore e forma:SolidPeso molecolare:484.45Vopikitug
CAS:Vopikitug is a humanized monoclonal antibody targeting IL-2RA with antitumor activity. It can be used to study cancer.Purezza:99.1% (SDS-PAGE); 96.5% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.5% (SEC-HPLC)Colore e forma:LiquidEtokimab
CAS:<p>Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.</p>Purezza:95%Colore e forma:LiquidA-802715
CAS:A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFormula:C16H26N4O3Purezza:96.29%Colore e forma:SolidPeso molecolare:322.4BI605906
CAS:<p>BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.</p>Formula:C17H22F2N4O3S2Purezza:97.14%Colore e forma:SolidPeso molecolare:432.51IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Formula:C18H12FN3O2Purezza:99.53% - 99.89%Colore e forma:SolidPeso molecolare:321.31Ref: TM-T36527
1mg47,00€5mg175,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)137,00€BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Formula:C18H15BrCl2N2O2Purezza:99.93%Colore e forma:SolidPeso molecolare:442.13Dersalazine
CAS:<p>Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.</p>Formula:C35H32N6O4Purezza:99.62%Colore e forma:SolidPeso molecolare:600.67NO-prednisolone
CAS:NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.Formula:C29H33NO9Purezza:98.65%Colore e forma:SolidPeso molecolare:539.57Ref: TM-T19480
1mg49,00€5mg109,00€10mg170,00€25mg298,00€50mg423,00€100mg593,00€200mg785,00€1mL*10mM (DMSO)130,00€NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Formula:C17H10F6N4O2Purezza:99.90%Colore e forma:SolidPeso molecolare:416.28Ref: TM-T12218
1mg47,00€5mg93,00€10mg142,00€25mg255,00€50mg378,00€100mg540,00€500mg1.074,00€1mL*10mM (DMSO)93,00€Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Formula:C37H40O9Purezza:93.08% - 99.34%Colore e forma:SolidPeso molecolare:628.71
