Ricettore IL
I recettori dell'interleuchina (recettori IL) sono un gruppo di recettori che si legano alle interleuchine, una famiglia di citochine che svolgono ruoli essenziali nella regolazione del sistema immunitario, nell'infiammazione e nell'ematopoiesi. La disregolazione della segnalazione delle interleuchine è associata a varie malattie infiammatorie e autoimmuni, rendendo i recettori IL bersagli critici per l'intervento terapeutico. Gli antagonisti dei recettori IL sono studiati per il trattamento di condizioni come l'artrite reumatoide, la psoriasi e le malattie infiammatorie intestinali. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori IL di alta qualità per supportare la tua ricerca sulla segnalazione delle citochine, sull'immunologia e sulla terapia delle malattie infiammatorie.
Trovati 85 prodotti di "Ricettore IL"
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AF 12198 Acetate
AF 12198 Acetate is a novel low molecular weight antagonist of IL-1Formula:C98H127N19O24Purezza:95.27%Colore e forma:SolidPeso molecolare:1955.17YM-90709
CAS:YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor.Formula:C22H21N3O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:359.42Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Formula:CH10Cl2Na2O10P2Purezza:98%Colore e forma:SolidPeso molecolare:360.92Suplatast (Tosilate)
CAS:Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis.Formula:C23H33NO7S2Purezza:99.34% - 99.65%Colore e forma:White Or Off-White CrystalsPeso molecolare:499.64Apilimod mesylate
CAS:Apilimod mesylate (STA 5326 mesylate) is a potent IL-12/IL-23 inhibitor.Formula:C25H34N6O8S2Purezza:99.51% - ≥95%Colore e forma:SolidPeso molecolare:610.7Satralizumab
CAS:Satralizumab (SA-237) is a humanized antibody targeting interleukin-6 (IL-6), used in research on neuromyelitis optica spectrum disorder (NMOSD).Purezza:95%Colore e forma:LiquidPeso molecolare:143.42 kDaInolimomab
CAS:Inolimomab is a monoclonal antibody targeting CD25 (IL-2R α chain) for studying acute graft-versus-host disease (aGVHD).Purezza:95% - >95.0% (SDS-PAGE); 99.49% (SEC-HPLC)Colore e forma:LiquidAnti-Mouse IL-6R Antibody (15A7)
Anti-Mouse IL-6R Antibody (15A7) is an antibody inhibitor targeting mouse IL-6R, derived from rats, widely used in research and experimentsPurezza:99% - 99%Colore e forma:Odour LiquidAfasevikumab
CAS:Afasevikumab (RG 7624) is a fully humanised monoclonal antibody that targets and neutralises IL-17A and IL-17F,autoimmune diseases and inflammation.Purezza:95%Colore e forma:LiquidPeso molecolare:146.07 kDaGevokizumab
CAS:Gevokizumab (S-78989) is a humanised monoclonal antibody targeting IL-1β, allosteric regulation, diabetes, cancer, inflammation, and cardiovascular diseases.Purezza:95%Colore e forma:LiquidPeso molecolare:144.93 kDaAnrukinzumab
CAS:Anrukinzumab (IMA-638) is an anti-IL-13 mAb with anti-inflammatory effects, in development for ulcerative colitis and asthma.Purezza:95%Colore e forma:LiquidPeso molecolare:145.38 kDaZiralimumab
CAS:Ziralimumab（ABX-RB2） is a monoclonal antibody that targets and inhibits IL-2 receptor, thereby modulating the immune response.Purezza:95%Colore e forma:LiquidGumokimab
CAS:Gumokimab (AK 111) is an anti-IL-17A mAb that blocks pro-inflammatory signaling, a candidate for psoriasis and ankylosing spondylitis.Purezza:95%Colore e forma:LiquidPeso molecolare:146.50 kDaTirnovetmab
CAS:Tirnovetmab (KIND-016) is a fully dog-derived monoclonal antibody targeting IL-31 with high affinity, suitable for investigating canine atopic dermatitis.Purezza:95% - 96.6% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:148.83 kDaEbdarokimab
CAS:Ebdarokimab (anti-IL-12/23 p40 mAb) inhibits the IL-12/IL-23 pathway and is under clinical investigation for SLE and plaque psoriasis.Purezza:95%Colore e forma:LiquidPeso molecolare:145.66 kDaEtokimab
CAS:Etokimab (ANB-020) is a humanised monoclonal antibody targeting IL-33, neutrophil migration, atopic dermatitis, asthma, and sinusitis.
Purezza:95%Colore e forma:LiquidD228
CAS:D228 is an oral anti-inflammatory,inhibi B and T lymphocytes, down-regulation of MyD88/TRAF6/p38 and up-regulation of IL-10,inflammatory bowel disease (IBD).Formula:C22H28O12Purezza:99.91%Colore e forma:SolidPeso molecolare:484.45BI605906
CAS:BI605906 is an IKKβ inhibitor that can be used to study inflammatory skin diseases such as psoriasis.
Formula:C17H22F2N4O3S2Purezza:97.14%Colore e forma:SolidPeso molecolare:432.51A-802715
CAS:A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases theFormula:C16H26N4O3Purezza:96.29%Colore e forma:SolidPeso molecolare:322.4LMT-28
CAS:LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2.Formula:C17H29NO4Purezza:97.55%Colore e forma:SolidPeso molecolare:311.42IL-4-inhibitor-1
CAS:IL-4 inhibitor: Binds IL-4 (Kd=1.8 μM), blocks activity (EC50=1.81 μM), selective vs. IL-13, stops IL-4-JAK1-STAT6 in THP-1 monocytes (EC50=3.1 μM).Formula:C18H12FN3O2Purezza:99.53% - 99.89%Colore e forma:SolidPeso molecolare:321.31Ref: TM-T36527
1mg47,00€5mg175,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)137,00€BIRT-377
CAS:BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).Formula:C18H15BrCl2N2O2Purezza:99.93%Colore e forma:SolidPeso molecolare:442.13Dersalazine
CAS:Dersalazine, a PAF inhibitor, reduces IL-17 to treat colitis in rodents, potentially aiding ulcerative colitis patients.
Formula:C35H32N6O4Purezza:99.62%Colore e forma:SolidPeso molecolare:600.67NO-prednisolone
CAS:NO-prednisolone (NCX-1015) is a compound that effectively stimulates the production of IL-10 in vivo.Formula:C29H33NO9Purezza:98.65%Colore e forma:SolidPeso molecolare:539.57Ref: TM-T19480
1mg49,00€5mg109,00€10mg170,00€25mg298,00€50mg423,00€100mg593,00€200mg785,00€1mL*10mM (DMSO)130,00€NFAT Transcription Factor Regulator-1
CAS:NFAT Transcription Factor Regulator-1 is an synthesis inhibitor of IL-2 (IC50 of 182 nM).Formula:C17H10F6N4O2Purezza:99.90%Colore e forma:SolidPeso molecolare:416.28Ref: TM-T12218
1mg47,00€5mg93,00€10mg142,00€25mg255,00€50mg378,00€100mg540,00€500mg1.074,00€1mL*10mM (DMSO)93,00€Resiniferatoxin
CAS:Resiniferatoxin ((+)-Resiniferatoxin) is a highly potent synthetic TRPV1 agonist.Cost-effective and quality-assured.Formula:C37H40O9Purezza:93.08% - 99.34%Colore e forma:SolidPeso molecolare:628.71IL-2-IN-1
CAS:IL-2-IN-1 is a potent inhibitor of IL-2 (IC50: 1978 nM) and exhibits anti-proliferative effects.Formula:C17H12F6N4O2Purezza:99.6%Colore e forma:SolidPeso molecolare:418.29IL-17A antagonist 3
CAS:IL-17A antagonist 3 is an IL-17A antagonist.Formula:C33H33ClN6O4Purezza:98%Colore e forma:SolidPeso molecolare:613.11Netakimab
CAS:Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.Purezza:95%Colore e forma:LiquidPeso molecolare:145.74 kDaCVN293
CAS:CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microgliaFormula:C14H10FN7OPurezza:99.50%Colore e forma:SolidPeso molecolare:311.27SP4206
CAS:SP4206 is an interaction inhibitor of IL-2/IL-2Rα (IL-2 and IL-2Rα with Kd of 70 nM and 10 nM,respectively)Formula:C30H37Cl2N7O6Purezza:98%Colore e forma:SolidPeso molecolare:662.56TMC353121
CAS:TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9).Formula:C32H42N6O3Purezza:≥98%Colore e forma:SolidPeso molecolare:558.71NDI-034858
CAS:NDI-034858 (TAK-279) is a tyrosine kinase 2 (TYK2) inhibitor (Kd<200 pM) that targets the JH2 structural domain of Tyk2 for the treatment of autoimmune diseasesFormula:C23H24N8O3Purezza:>99.99%Colore e forma:SolidPeso molecolare:460.49α-Terpineol
CAS:Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
Formula:C10H18OPurezza:97.55%Colore e forma:Colorless LiquidPeso molecolare:154.25Ref: TM-FR14115
Prodotto fuori produzioneDi-O-methyldemethoxycurcumin
CAS:Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.Formula:C22H22O5Purezza:98%Colore e forma:SolidPeso molecolare:366.41
