MAPK
Le MAPK sono una famiglia di chinasi proteiche coinvolte in una varietà di processi cellulari, tra cui crescita, proliferazione, differenziazione e risposte allo stress. La via di segnalazione MAPK è composta da diversi livelli, tra cui ERK, JNK e p38 MAPK, ciascuno con ruoli distinti nella funzione cellulare. La disregolazione della segnalazione MAPK è collegata al cancro, alle malattie infiammatorie e ai disturbi metabolici. Presso CymitQuimica, offriamo una vasta gamma di inibitori e attivatori delle MAPK per supportare la tua ricerca in biologia cellulare, trasduzione del segnale e meccanismi delle malattie.
Trovati 896 prodotti di "MAPK"
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JX 401
CAS:JX 401 is a p38α inhibitor.Formula:C21H25NO2SPurezza:98%Colore e forma:SolidPeso molecolare:355.49SB 204900
CAS:SB 204900 inhibit the release of histamine and TNF-α from RBL-2H3 cells.Formula:C18H17NO2Colore e forma:SolidPeso molecolare:279.33HPK1-IN-29
CAS:"HPK1-IN-29 suppresses HPK1, boosting anti-tumor immunity; potential for immune disease research."Formula:C26H18F3N5O2Colore e forma:SolidPeso molecolare:489.45DDO3711
CAS:"DDO3711, a PHORC, links an ASK1 inhibitor to a PP5 activator, inhibiting ASK1 (IC50=164.1 nM), dephosphorylating p-ASK1, and showing anti-cancer potential."Formula:C42H41N9O6Colore e forma:SolidPeso molecolare:767.83KRAS G12C inhibitor 29
CAS:KRAS G12C inhibitor 29 is an inhibitor of KRAS G12C and can be used to study cancer.Formula:C23H21ClFN5O2Colore e forma:SolidPeso molecolare:453.98-CPT-2Me-cAMP, sodium salt
CAS:8-CPT-2Me-cAMP sodium activates Epac GEFS, targets Rap1/2, has 2.2 μM EC50 for Epac1, doesn't activate PKA, and prompts Ca2+ release in β-cells.Formula:C17H16ClN5NaO6PSColore e forma:SolidPeso molecolare:507.82SCH-53870
CAS:SCH-53870 inhibits p21-hRas nucleotide exchange in vitro.Formula:C18H18N2O4SColore e forma:SolidPeso molecolare:358.41KRAS inhibitor-16
CAS:KRAS inhibitor-16 blocks KRAS G12C and p-ERK in cancer cells; potential for pancreatic, colorectal, lung cancer treatment. IC50: 0.457 μM.Formula:C20H16Cl2FN3O2SColore e forma:SolidPeso molecolare:452.33SOS1-IN-12
CAS:SOS1-IN-12 is a potent inhibitor of SOS1, acting on SOS1 (Ki: 0.11 nM) and on pERK (IC50: 47 nM).Formula:C23H26F3N5Colore e forma:SolidPeso molecolare:429.48MTBT
CAS:MTBT is the proliferation of cancer cells inhibitor. It induces cell cycle arrest and activates p38 MAPK.Formula:C14H11NO2S2Colore e forma:SolidPeso molecolare:289.37ARS-2102
CAS:ARS-2102 is a potent covalent KRAS G12C inhibitor for use in cancer research .Formula:C28H31ClF2N6O2Colore e forma:SolidPeso molecolare:557.03ERK5-IN-4
CAS:ERK5-IN-4 (34b) is a potent, specific ERK5 inhibitor; IC50: 77 nM full-length, 300 nM ΔTAD in HEK293 cells.Formula:C16H11Cl2FN4O2Colore e forma:SolidPeso molecolare:381.19KRAS inhibitor-15
CAS:KRAS inhibitor-15 blocks KRAS G12C and p-ERK in cancer cells; potent against pancreatic and lung cancers. IC50: 0.954 μM (KRAS), 2.03/>33.3 μM (p-ERK).Formula:C20H17Cl2FN4OSColore e forma:SolidPeso molecolare:451.34(S)-p38 MAPK Inhibitor III
CAS:(S)-p38 MAPK inhibitor III: a cell-permeable, methylsulfanylimidazole; IC50s: 0.90 µM for p38 MAPK, 0.37 µM TNF-α, 0.044 µM IL-1β.Formula:C23H21FN4SColore e forma:SolidPeso molecolare:404.5(R)-PD 0325901CL
CAS:(R)-PD 0325901CL, a PD 0325901CL isomer, is a MEK inhibitor used in cancer research, effective against cancer cells in vitro and in vivo.Formula:C16H14ClF2IN2O4Colore e forma:SolidPeso molecolare:498.65RAS inhibitor Abd-7
CAS:Abd-7: potent RAS inhibitor (Kd=51 nM) that blocks RAS-effector PPI, disrupting KRAS, NRAS Q61H, HRAS G12V signaling.Formula:C23H25N3O3Colore e forma:SolidPeso molecolare:391.46RAF-IN-1
CAS:RAF-IN-1: strong b/cRAF inhibitor; cRAF IC50=3.8 nM; bRAFwt IC50=36 nM; bRAFV600E IC50=29.4 nM; A375/H358 bRAFV600E GI50=3.4/2.9 nM.Formula:C26H22F3N3O4Colore e forma:SolidPeso molecolare:497.47KRAS inhibitor-4
CAS:KRAS inhibitor-4 developed as anticancer agents, is a potent KRAS inhibitor.Formula:C30H39ClN8OPurezza:98%Colore e forma:SolidPeso molecolare:563.14Anti-inflammatory agent 33
CAS:Agent 33: potent p38α inhibitor, reduces NO, iNOS, COX-2, p-p38α, p-MK2; shows anti-inflammatory effects.Formula:C22H15N3O5SColore e forma:SolidPeso molecolare:433.44RSK2-IN-3
CAS:<p>RSK2-IN-3 (Compound 26) is a covalent, reversible inhibitor of RPS6KA3 (RSK2) kinase.</p>Formula:C24H26N4O5Colore e forma:SolidPeso molecolare:450.49
