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MAPK

MAPK

Le MAPK sono una famiglia di chinasi proteiche coinvolte in una varietà di processi cellulari, tra cui crescita, proliferazione, differenziazione e risposte allo stress. La via di segnalazione MAPK è composta da diversi livelli, tra cui ERK, JNK e p38 MAPK, ciascuno con ruoli distinti nella funzione cellulare. La disregolazione della segnalazione MAPK è collegata al cancro, alle malattie infiammatorie e ai disturbi metabolici. Presso CymitQuimica, offriamo una vasta gamma di inibitori e attivatori delle MAPK per supportare la tua ricerca in biologia cellulare, trasduzione del segnale e meccanismi delle malattie.

Trovati 894 prodotti di "MAPK"

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  • AZD6703 free base
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    AZD6703 free base

    CAS:
    AZD6703 is a potent, selective and reversible orally bioavailable inhibitor of p38 mitogen-activated protein kinase 14 (MAPK14).
    Formula:C24H27N5O2
    Colore e forma:Solid
    Peso molecolare:417.5

    Ref: TM-T26721

  • Kobe2601
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    Kobe2601

    CAS:
    Kobe2601 is a Kobe0065 and Kobe02602 water-soluble analog. It displays inhibitory activity towards Ras-Raf binding.
    Formula:C13H10FN5O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:351.31

    Ref: TM-T24267

  • Nek2-IN-6
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    Nek2-IN-6

    CAS:
    Nek2-IN-6 inhibitor .
    Formula:C33H33F3N6O4S
    Colore e forma:Solid
    Peso molecolare:666.71

    Ref: TM-T73287

  • GSK329
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    GSK329

    CAS:
    GSK329 selectively inhibits TNNI3K, showing cardioprotection in ischemic heart models.
    Formula:C19H14Cl2F3N5O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:472.25

    Ref: TM-T24109

  • HCI-2184
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    HCI-2184

    CAS:
    HCI-2184 is an inhibitor of AXL kinase and Nek2 that acts by successfully mitigating drug resistance in bortezomib-resistant multiple myeloma.
    Formula:C23H28ClN7O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:502.03

    Ref: TM-T24130

  • GSK649A
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    GSK649A

    CAS:
    GSK649A is a novel activator of Satellite Cell Proliferation, it could enhance repair of Damaged Muscle.
    Formula:C15H12ClFN6OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:378.81

    Ref: TM-T27486

  • CP-281384
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    CP-281384

    CAS:
    CP-281384 is a potent, p38alpha-selective inhibitor.
    Formula:C18H14F2N4O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:340.33

    Ref: TM-T27062

  • RBC6
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    RBC6

    CAS:
    RBC6 is an inhibitor of the binding of Ral to its effector RALBP1.
    Formula:C16H14Cl2N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:365.21

    Ref: TM-T24707

  • CP-944629
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    CP-944629

    CAS:
    CP-944629 is a novel, potent, and selective inhibitor of p38alpha.
    Formula:C19H15F3N4O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:372.34

    Ref: TM-T27067

  • BNC-1
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    BNC-1

    CAS:
    BNC-1 reduces amyloid in mice, enhances synapses by activating Elk-1.
    Formula:C16H14N2O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:282.29

    Ref: TM-T26879

  • TOPK-p38/JNK-IN-1
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    TOPK-p38/JNK-IN-1

    CAS:
    TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, with an IC50 value of 2.14 μM for the inhibition of NO
    Formula:C17H15F3N2O4
    Colore e forma:Solid
    Peso molecolare:368.31

    Ref: TM-T61440

  • ERK1/2 inhibitor 1
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    ERK1/2 inhibitor 1

    CAS:
    <p>ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.</p>
    Formula:C29H32ClN5O4
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:550.05

    Ref: TM-T11226

  • PF-05381941
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    PF-05381941

    CAS:
    PF-05381941 is a selective and potent dual inhibitor of TAK1 and p38α that inhibits the kinase activity of TAK1 by binding to its active site.
    Formula:C27H26N6O2
    Purezza:98.04%
    Colore e forma:Solid
    Peso molecolare:466.53

    Ref: TM-T36017

  • MEK-IN-1
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    MEK-IN-1

    CAS:
    MEK-IN-1 is a MEK inhibitor.
    Formula:C24H20N4O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:428.44

    Ref: TM-T10675

  • PAF (C16)
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    PAF (C16)

    CAS:
    <p>PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability.</p>
    Formula:C26H54NO7P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:523.68

    Ref: TM-T21547

  • B-Raf IN 13
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    B-Raf IN 13

    CAS:
    <p>B-Raf IN 13 is a potent B-Raf inhibitor with anticancer activity.B-Raf IN 13 has an IC50 of 3.55 nM in the BRAF V600E enzyme assay.</p>
    Formula:C19H19ClFN3O4S
    Purezza:99.41% - >99.99%
    Colore e forma:Soild
    Peso molecolare:439.89

    Ref: TM-T67862

  • KRAS G12D inhibitor 10
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    KRAS G12D inhibitor 10

    CAS:
    KRAS G12D inhibitor 10 targets KRAS G12D in cancer research (WO2021108683A1, compound 34).
    Formula:C33H41ClN8O2
    Colore e forma:Solid
    Peso molecolare:617.18

    Ref: TM-T72345

  • L-167307
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    L-167307

    CAS:
    L-167307 is a p38 kinase inhibitor.
    Formula:C22H17FN2OS
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:376.45

    Ref: TM-T24368

  • KRAS4b-IN-D14
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    KRAS4b-IN-D14

    CAS:
    KRAS4b-IN-D14 inhibits oncogenic KRAS4b, shrinks tumors, and induces cancer cell apoptosis.
    Formula:C24H24ClN5O4
    Colore e forma:Solid
    Peso molecolare:481.93

    Ref: TM-T71717

  • HPK1-IN-15
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    HPK1-IN-15

    CAS:
    HPK1-IN-15 selectively inhibits HPK1, a MAP4K family kinase, potentially aiding in cancer treatment.
    Formula:C24H21ClF3N5
    Colore e forma:Solid
    Peso molecolare:471.91

    Ref: TM-T63046