ERK
ERK è una proteina chiave nella via di segnalazione MAPK (Mitogen-Activated Protein Kinase), coinvolta nella trasmissione dei segnali dai recettori di superficie cellulare al DNA nel nucleo della cellula. ERK svolge un ruolo cruciale nella regolazione di vari processi cellulari, tra cui la proliferazione, la differenziazione e la sopravvivenza. La disregolazione della segnalazione ERK è associata allo sviluppo del cancro e di altre malattie, rendendola un importante bersaglio per l'intervento terapeutico. Presso CymitQuimica, offriamo una selezione di inibitori e modulatori di ERK di alta qualità per supportare la tua ricerca sulla segnalazione cellulare, oncologia e sviluppo terapeutico.
Trovati 236 prodotti per "ERK".
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Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Formula:C17H17ClF6N2OPurezza:99% - 99.99%Colore e forma:SolidPeso molecolare:414.77Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormula:C13H8O3Purezza:99.45%Colore e forma:SolidPeso molecolare:212.2008LUT014
CAS:LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions associated with EGFR Inhibitors treatment.Formula:C27H19F3N8OPurezza:99.03%Colore e forma:Yellow SolidPeso molecolare:528.488Methylthiouracil
CAS:Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.Formula:C5H6N2OSPurezza:98.82% - 99.89%Colore e forma:SolidPeso molecolare:142.179MRTX-1257
CAS:MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% target engagement.Formula:C33H39N7O2Purezza:96.76% - 97.3%Colore e forma:Yellow SolidPeso molecolare:565.7085MK2-IN-3 hydrate
CAS:MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM)Formula:C21H18N4O2Purezza:99.58%Colore e forma:SolidPeso molecolare:358.3932AX-15836
CAS:AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).Formula:C32H40N8O5SPurezza:98.96%Colore e forma:SolidPeso molecolare:648.776Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Formula:C17H16F6N2OPurezza:99.89%Colore e forma:SolidPeso molecolare:378.3122CC-90003
CAS:CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.Formula:C22H21F3N6O2Purezza:99.42%Colore e forma:SolidPeso molecolare:458.4363PD 198306
CAS:PD 198306: a MEK inhibitor with antihyperalgesic properties, reduces Streptozocin-boosted active ERK1.Formula:C18H16F3IN2O2Purezza:99.66%Colore e forma:SolidPeso molecolare:476.23Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Formula:C14H22N2OPurezza:99.88% - >99.99%Colore e forma:White SolidPeso molecolare:234.3373ERK5-IN-5
CAS:ERK5-IN-5 is extracellular signal-regulated kinase 5 (ERK5) inhibitor with anticancer activity anticonvulsant activity inhibits A549 cell proliferation.Formula:C19H16ClN3OPurezza:99.89%Colore e forma:SolidPeso molecolare:337.8(E/Z)-BCI
CAS:(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROSFormula:C22H23NOPurezza:99.94%Colore e forma:White SolidPeso molecolare:317.4241ERK5-IN-6
CAS:ERK5-IN-6 is an ERK5 kinase inhibitor with antiproliferative, anticonvulsant, and antitumor activity for the study of central nervous system related diseases.Formula:C23H21N3Purezza:99.87%Colore e forma:SolidPeso molecolare:339.43Honokiol
CAS:Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.Formula:C18H18O2Purezza:99.65% - 99.94%Colore e forma:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TastePeso molecolare:266.3343Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Formula:C14H22N2O·HCl·H2OPurezza:99.95%Colore e forma:SolidPeso molecolare:288.82BAY 2965501
CAS:BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation.BAY 2965501 can be used in the study of cancer.Formula:C20H19FN4O3SPurezza:99.89%Colore e forma:SolidPeso molecolare:414.453VSLRGDTRG
CAS:VSLRGDTRG is a synthetic peptide derived from the RGD motif in cadherin17 (CDH17) that binds to the α2β1 integrin, activating its signaling pathways. By promoting high-affinity conformational changes in β1 integrins through the RGD motif, VSLRGDTRG enhances cell adhesion and the phosphorylation of FAK and ERK1/2, thereby driving tumor proliferation and metastasis. This peptide is useful for research on cancers expressing CDH17, such as colorectal and pancreatic cancer.Formula:C38H69N15O14Colore e forma:SolidPeso molecolare:960.047HRS 4642
CAS:HRS 4642 is a selective KRAS G12D inhibitor with a Kd value of 0.083 nM, antitumour, inhibits phosphorylation of downstream MEK and ERK proteins.Formula:C34H35F3N6O3Purezza:99.17%Peso molecolare:632.68Rineterkib hydrochloride
CAS:Rineterkib hydrochloride (B) is an oral RAF/ERK1/2 inhibitor for MAPK-driven cancers, including KRAS/BRAF-mutant NSCLC and CRC.Formula:C26H28BrClF3N5O2Colore e forma:SolidPeso molecolare:614.89
