CFTR
CFTR è una proteina canale del cloruro che regola il trasporto di ioni cloruro e bicarbonato attraverso le membrane delle cellule epiteliali, svolgendo un ruolo cruciale nel mantenimento dell'equilibrio dei fluidi nei tessuti. Le mutazioni nel gene CFTR portano alla fibrosi cistica, un disturbo genetico caratterizzato dalla produzione di muco denso che può ostruire le vie respiratorie e causare gravi problemi respiratori e digestivi. Presso CymitQuimica, offriamo una selezione di modulatori CFTR per supportare la tua ricerca sulla fibrosi cistica, sul trasporto ionico e sui disturbi genetici.
Trovati 66 prodotti di "CFTR"
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CFTR corrector 6
CAS:CFTR corrector 6, a potent CFTR potentiator, aids cystic fibrosis research and related disorders.Formula:C22H13F4N9Colore e forma:SolidPeso molecolare:479.39CP 154526
CAS:<p>CRF1 receptor antagonist</p>Formula:C23H33ClN4Purezza:98%Colore e forma:SolidPeso molecolare:400.99CFTR corrector 12
CAS:<p>CFTR corrector 12 is a CFTR corrector that rescues all mutant proteins except M760R ABCA3 and can be used to study cystic fibrosis.</p>Formula:C19H21ClN4O2S2Purezza:99.47%Colore e forma:SolidPeso molecolare:436.98DNDS
CAS:DNDS is a channel blocker of voltage-dependent cystic fibrosis transmembrane conductance regulator (CFTR).Formula:C14H8N2Na2O10S2Purezza:99.92%Colore e forma:Physical Description White Powder (Ntp 1992)Peso molecolare:474.33(R)-Vanzacaftor
CAS:(R)-Vanzacaftor ((R)-VX-121) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator [1].Formula:C32H39N7O4SColore e forma:SolidPeso molecolare:617.76Chromanol 293B
CAS:slow delayed rectifier K+ current (IKs) blockerFormula:C15H20N2O4SPurezza:98%Colore e forma:SolidPeso molecolare:324.4BPO-27 racemate
CAS:BPO-27 racemate (BPO-27 (racemate)) is an effective CFTR inhibitor with IC50 of 8 nM.Formula:C26H18BrN3O6Purezza:97.67% - 98.86%Colore e forma:SolidPeso molecolare:548.34CRF1 receptor antagonist-1
CAS:CRF1 Receptor Antagonist-1 (Compound 2), a CRF1 receptor antagonist, is utilized in research pertaining to congenital adrenal hyperplasia (CAH) [1].Formula:C27H28ClFN2O2SPurezza:98%Colore e forma:SolidPeso molecolare:499.04(R)-Elexacaftor
CAS:(R)-Elexacaftor (compound 37) is the enantiomer of Elexacaftor (compound 1). (R)-Elexacaftor is a CFTR modulator with an EC50 of 0.29 μM for CFTR dF508.Formula:C26H34F3N7O4SPurezza:98.991%Colore e forma:SolidPeso molecolare:597.65CFTR corrector 4
CAS:Potent, oral CFTR corrector 4 targets cystic fibrosis, increasing cell surface CFTR levels.Formula:C29H27F2NO7Purezza:99.32%Colore e forma:SolidPeso molecolare:539.52CFTR corrector 15
CAS:<p>CFTR Corrector 15 (Compound 4172) serves as a corrector for cystic fibrosis transmembrane conductance regulator (CFTR). When used in combination with VX-809, it addresses the folding defects of F508del-CFTR. CFTR Corrector 15 is also applicable in the research of cystic fibrosis.</p>Formula:C24H22ClN5O2SColore e forma:SolidPeso molecolare:479.98Crinecerfont tosylate
CAS:Crinecerfont tosylate is an effective oral CRF1 receptor antagonist. It is applicable to studies involving congenital adrenal hyperplasia (CAH).Formula:C34H36ClFN2O4S2Colore e forma:SolidPeso molecolare:655.242CFTR corrector 16
CAS:<p>CFTRcorrector 16 (Compound 39) is a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR), utilized in the research of cystic fibrosis disease.</p>Formula:C27H26ClN5O2SColore e forma:SolidPeso molecolare:520.05ARN23765
CAS:<p>ARN23765 is an F508del-CFTR corrector with an EC50 of 38 pM in human bronchial epithelial cells. It enhances the maturation and function of F508del-CFTR at the cell membrane, influencing ion transport and secretion, thereby addressing the pathological mechanisms of cystic fibrosis (CF).</p>Formula:C30H22F5N3O6Colore e forma:SolidPeso molecolare:615.504CFTR corrector 18
CAS:CFTRcorrector 18 (Compound I-99) acts as a modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It enhances the processing and trafficking of CFTR, thereby increasing the amount of CFTR present on the cell surface. CFTRcorrector 18 holds potential for research in cystic fibrosis (CF).Formula:C38H40N6O5SColore e forma:SolidPeso molecolare:692.826CFTR corrector 17
CAS:CFTRcorrector 17 (example 17) is a regulator of the cystic fibrosis transmembrane conductance regulator (CFTR). It is utilized in the study of diseases mediated by CFTR.Formula:C18H15FN2O2Colore e forma:SolidPeso molecolare:310.32
