Canale TRP/TRPV

Methyl syringate (Syringic Acid Methyl Ester) has a unique inhibitory activity toward aflatoxin production with …

AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 …

MK6-83 is the transient receptor potential channel ML3 agonist.

9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated …

TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells …

Hydroxy-α-sanshool is an alkyl amide isolated from the pepper. It acts as a TRPA1 covalent …

A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist

WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 …

LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.

ML-SA1 (Mucolipin synthetic agonist 1) is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) …

Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the …

SN 2 is a novel and potent TRPML3 ion channel activator(EC50 = 1.13 μM). SN …

SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of …

MK-2295 is a potent TRPV1 antagonist. MK-2295 can be used in studies about the treatment …

AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe …

ASP7663 is a TRPA1 Receptor Agonist and exhibiting an abdominal analgesic effect in vivo.

M084 (N-Butyl-1H-benzimidazol-2-amine) is a blocker of TRPC4/5 channel, with antidepressant and anxiolytic effects.

CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of …

AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin …

ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.

ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 …

Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.

TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).

TRPM4-IN-2 (NBA), also known as NBA, is a highly effective inhibitor of transient receptor potential …

TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological …

AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).

JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).

EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel …

PF-05105679 is a selective TRPM8 antagonist (IC50 = 103 nM). PF-05105679 can be used in …

Mesendogen is an inhibitor of transient receptor potential cation channel, subfamily M, member 6 (TRPM6) …

A-1165442 is a competitive TRPV1 antagonist. For human TRPV, the IC50 values is 9 nM.

GSK3395879 is a selective and orally bioavailable antagonist of transient receptor potential vanilloid-4 (TRPV4) (IC50: …

TRPA1 Antagonist 1 is an antagonist of TRPA1(IC50: 8 nM) and is a methylene phosphate …

GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: …

Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.

Voacangine is a selective and potent antagonist of TRPV1 and TRPM8, and an agonist of …