Canale TRP/TRPV
canali TRP (Transient Receptor Potential), inclusa la sottofamiglia TRPV, sono un gruppo di canali ionici coinvolti in vari processi sensoriali, come la percezione della temperatura, la sensazione del dolore e l'osmoregolazione. I canali TRP sono ampiamente espressi in diversi tessuti e svolgono un ruolo nelle risposte fisiologiche agli stimoli ambientali. In particolare, i canali TRPV sono coinvolti nel rilevamento dei cambiamenti di temperatura e sono implicati in condizioni come il dolore cronico, l'infiammazione e il cancro. Presso CymitQuimica, offriamo una gamma completa di modulatori dei canali TRP/TRPV per supportare la tua ricerca in biologia sensoriale, gestione del dolore e trasduzione del segnale.
Trovati 93 prodotti di "Canale TRP/TRPV"
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Pico145
CAS:<p>Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels.</p>Formula:C23H20ClF3N4O5Purezza:99.06%Colore e forma:SolidPeso molecolare:524.88TRPM4-IN-1
CAS:<p>TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.</p>Formula:C15H11Cl2NO4Purezza:97.22%Colore e forma:SolidPeso molecolare:340.16MK6-83
CAS:<p>MK6-83 is the transient receptor potential channel ML3 agonist.</p>Formula:C16H20N2O2S2Purezza:99.5%Colore e forma:SolidPeso molecolare:336.479-Phenanthrol
CAS:<p>9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.</p>Formula:C14H10OPurezza:98.48%Colore e forma:SolidPeso molecolare:194.23TC-I2000
CAS:<p>TC-I2000 is an TRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells with IC50 of 53 nM.</p>Formula:C23H18F4N2OPurezza:99.778%Colore e forma:SolidPeso molecolare:414.4ML204 hydrochloride
CAS:<p>ML204 hydrochloride (ML204 HCl) is a TRPC4/TRPC5 channel antagonist.</p>Formula:C15H19ClN2Colore e forma:SolidPeso molecolare:262.78WS-12
CAS:<p>WS-12 is a potent TRPM8 agonist that acts as a cooling agent (EC50 : 193 nM)</p>Formula:C18H27NO2Purezza:99.99%Colore e forma:Whitish To White Solid CrystallinePeso molecolare:289.41Pyr10
CAS:<p>Pyr10, a pyrazole derivative, selectively inhibits TRPC3, not STIM1/Orai1, with IC50 of 0.72 μM in TRPC3-HEK293, and 13.08 μM in BRL-2H3 cells.</p>Formula:C18H13F6N3O2SPurezza:99.69% - 99.7%Colore e forma:SolidPeso molecolare:449.37SB-705498
CAS:<p>SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.</p>Formula:C17H16BrF3N4OPurezza:99.57% - ≥95%Colore e forma:SolidPeso molecolare:429.23Vanilloid receptor antagonist 1
CAS:<p>Vanilloid receptor antagonist 1 (4-(7-Hydroxy-2-isopropyl-4-oxoquinazolin-3(4H)-yl)benzonitrile) is a potent vanilloid receptor TRPV1 antagonist.</p>Formula:C18H15N3O2Purezza:98.14%Colore e forma:SolidPeso molecolare:305.33AMG9810
CAS:<p>AMG 9810 blocks capsaicin's action on TRPV1; human IC50=24.5 nM, rat IC50=85.6 nM.</p>Formula:C21H23NO3Purezza:99.79% - 99.95%Colore e forma:SolidPeso molecolare:337.41Optovin
CAS:<p>Optovin is a TRPA1 activator, which is reversibly photoactivated.</p>Formula:C15H13N3OS2Purezza:99.47% - 99.67%Colore e forma:SolidPeso molecolare:315.41MDR-652
CAS:<p>MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for</p>Formula:C22H23ClFN3O2SPurezza:99.96%Colore e forma:SolidPeso molecolare:447.95RN-1747
CAS:<p>RN-1747: TRPV4 agonist (EC50: human 0.77 μM, mouse 4.0 μM, rat 4.1 μM), TRPM8 antagonist (IC50: 4 μM).</p>Formula:C17H18ClN3O4SPurezza:99.29%Colore e forma:SolidPeso molecolare:395.86AMTB hydrochloride
CAS:<p>AMTB HCl: Novel TRPM8 blocker, relieves pain, treats urinary issues, moderates bladder reflexes in rats.</p>Formula:C23H27ClN2O2SPurezza:99.08%Colore e forma:SolidPeso molecolare:430.99TRPM8 antagonist 2
CAS:<p>TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.</p>Formula:C26H26N2O2Purezza:98.1%Colore e forma:SolidPeso molecolare:398.5AC1903
CAS:<p>AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.</p>Formula:C19H17N3OPurezza:98.45%Colore e forma:SolidPeso molecolare:303.36cim0216
CAS:<p>CIM0216 is a synthetic TRPM3 activator whose potency and apparent affinity greatly exceeds that of the canonical TRPM3 agonist.</p>Formula:C21H21N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:347.41AMG 517
CAS:<p>AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM) and heat activation (IC50: 1.3 nM) of TRPV1</p>Formula:C20H13F3N4O2SPurezza:99.77% - 99.85%Colore e forma:SolidPeso molecolare:430.4JNJ-28583113
CAS:<p>JNJ-28583113 is a TRPM2 antagonist, inducing phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death.</p>Formula:C19H21F3N2O2Purezza:98.57%Colore e forma:SolidPeso molecolare:366.38
