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Canale TRP/TRPV

Canale TRP/TRPV

canali TRP (Transient Receptor Potential), inclusa la sottofamiglia TRPV, sono un gruppo di canali ionici coinvolti in vari processi sensoriali, come la percezione della temperatura, la sensazione del dolore e l'osmoregolazione. I canali TRP sono ampiamente espressi in diversi tessuti e svolgono un ruolo nelle risposte fisiologiche agli stimoli ambientali. In particolare, i canali TRPV sono coinvolti nel rilevamento dei cambiamenti di temperatura e sono implicati in condizioni come il dolore cronico, l'infiammazione e il cancro. Presso CymitQuimica, offriamo una gamma completa di modulatori dei canali TRP/TRPV per supportare la tua ricerca in biologia sensoriale, gestione del dolore e trasduzione del segnale.

Trovati 93 prodotti di "Canale TRP/TRPV"

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  • SAR7334
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    SAR7334

    CAS:
    <p>SAR7334 (TRCP6-IN-1) is a potent and specific inhibitor of TRPC6(IC50 of 7.9 nM).</p>
    Formula:C21H22ClN3O
    Purezza:99.62% - 99.71%
    Colore e forma:Solid
    Peso molecolare:367.87

    Ref: TM-T12849

  • Logo CymitQuimica
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    N-Oleoyl Valine

    CAS:
    N-Oleoyl valine, an N-acyl amine, antagonizes TRPV3 for thermoregulation; rises post-cold exposure; elevates in mouse lung injury.
    Formula:C23H43NO3
    Peso molecolare:381.59

    Ref: TM-T35921

  • JYL 1421
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    JYL 1421

    CAS:
    <p>JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).</p>
    Formula:C20H26FN3O2S2
    Purezza:98.83%
    Colore e forma:Solid
    Peso molecolare:423.57

    Ref: TM-T15634

  • AM12
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    AM12

    CAS:
    <p>AM12 inhibits Lanthanide-evoked TRPC5 activity (IC50: 0.28 μM).</p>
    Formula:C15H9BrO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:349.13

    Ref: TM-T13546

  • TRPC6-PAM-C20
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    TRPC6-PAM-C20

    CAS:
    <p>TRPC6-PAM-C20, a selective enhancer for TRPC6, boosts calcium in HEK cells and OAG-related platelet clumping, EC50: 2.37μM.</p>
    Formula:C22H21NO4
    Purezza:98.16%
    Colore e forma:Solid
    Peso molecolare:363.41

    Ref: TM-T37428

  • D-3263 hydrochloride
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    D-3263 hydrochloride

    CAS:
    <p>D-3263 hydrochloride (D3263 HCl salt) is enteric-coated, orally bioavailable transient receptor potential melatonin member 8 (TRPM8) agonist.</p>
    Formula:C21H32ClN3O3
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:409.95

    Ref: TM-T10929L

  • TRPV3 antagonist 74a
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    TRPV3 antagonist 74a

    CAS:
    <p>TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.</p>
    Formula:C17H17F3N2O2
    Purezza:≥98.0%
    Colore e forma:Solid
    Peso molecolare:338.32

    Ref: TM-T37429

  • GSK1702934A
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    GSK1702934A

    CAS:
    <p>GSK1702934A is a TRPC3 agonist with pro-arrhythmic and positive inotropic effects and is used in the study of diabetes mellitus.</p>
    Formula:C22H25N3O2S
    Purezza:98.15%
    Colore e forma:Solid
    Peso molecolare:395.52

    Ref: TM-T15425

  • TRPM4-IN-2
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    TRPM4-IN-2

    CAS:
    <p>NBA, or TRPM4-IN-2, is a potent TRPM4 inhibitor with IC50 of 0.16 μM, used in prostate and colorectal cancer research.</p>
    Formula:C19H14ClNO4
    Purezza:99.21%
    Colore e forma:Solid
    Peso molecolare:355.77

    Ref: TM-T61275

  • Asivatrep
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    Asivatrep

    CAS:
    <p>Asivatrep (PAC14028) is a selective and potent antagonist of transient receptor potential vanilloid subtype 1 (TRPV1) for the study of atopic dermatitis.</p>
    Formula:C21H22F5N3O3S
    Purezza:95.13%
    Colore e forma:Solid
    Peso molecolare:491.48

    Ref: TM-T16426

  • RN9893
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    RN9893

    CAS:
    <p>RN9893 is a selective and potent TRPV4 receptor antagonist with IC50 values of 320, 420 and 660 nM for TRPV4 receptors in mouse, human and rat, respectively.</p>
    Formula:C21H23F3N4O5S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:500.49

    Ref: TM-T28548

  • TRPV4 agonist-1
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    TRPV4 agonist-1

    CAS:
    <p>TRPV4 agonist-1 is an agonist of TRPV4 (EC50: 60 nM in the hTRPV4 Ca2+ assay).</p>
    Formula:C25H23ClF2N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:484.93

    Ref: TM-T13214

  • ABT 102
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    ABT 102

    CAS:
    <p>ABT 102 (CHEMBL398338) is a selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptor.</p>
    Formula:C21H24N4O
    Purezza:98.38% - 99.86%
    Colore e forma:Solid
    Peso molecolare:348.44

    Ref: TM-T29522

  • Mavatrep
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    Mavatrep

    CAS:
    <p>Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.</p>
    Formula:C25H21F3N2O
    Purezza:98.51% - 99.31%
    Colore e forma:Solid
    Peso molecolare:422.44

    Ref: TM-T16014

  • SET 2
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    SET 2

    CAS:
    <p>SET 2 is an antagonist of transient receptor potential vanilloid type 2(TRPV2) with an IC50 of 0.46 μM. SET 2 shows selectivity over TRPV1, TRPV3 and TRPV4.</p>
    Formula:C17H21F3N4O2S
    Purezza:99.77%
    Colore e forma:Solid
    Peso molecolare:402.43

    Ref: TM-T37097

  • Elismetrep
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    Elismetrep

    CAS:
    <p>Elismetrep (MT-8554) is an orally available TRPM8 inhibitor with potential analgesic activity for the study of vasomotor symptoms in postmenopausal women.</p>
    Formula:C27H21F3N2O5S
    Purezza:99.37% - 99.93%
    Colore e forma:Solid
    Peso molecolare:542.53

    Ref: TM-T27253

  • MSP3
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    MSP3

    CAS:
    <p>MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.</p>
    Formula:C16H19NO3S
    Purezza:99.89%
    Colore e forma:Solid
    Peso molecolare:305.39

    Ref: TM-T28118

  • HC-070
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    HC-070

    CAS:
    <p>HC-070 is a TRPC5 and TRPC4 antagonist (IC50 = 9.3 nM and 46 nM).</p>
    Formula:C22H20Cl2N4O4
    Purezza:98.48%
    Colore e forma:Solid
    Peso molecolare:475.32

    Ref: TM-T15465

  • Pyr3
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    Pyr3

    CAS:
    <p>Pyr3 selectively blocks TRPC3 channels, reducing Ca2+ influx; it's effective at 700 nM.</p>
    Formula:C16H11Cl3F3N3O3
    Purezza:98.04%
    Colore e forma:Solid
    Peso molecolare:456.63

    Ref: TM-T16687

  • TC-I 2014
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    TC-I 2014

    CAS:
    <p>TC-I 2014 shows antiallodynic properties in pain models.</p>
    Formula:C23H19F6N3O
    Purezza:99.07%
    Colore e forma:Solid
    Peso molecolare:467.41

    Ref: TM-T17006