Canale del cloruro
I canali del cloruro sono proteine di membrana che controllano il movimento degli ioni cloruro attraverso le membrane cellulari, svolgendo un ruolo vitale nel mantenimento del volume cellulare, dell'eccitabilità elettrica e dell'equilibrio acido-base. La disfunzione dei canali del cloruro è legata a malattie come la fibrosi cistica, l'epilessia e i disturbi renali. Presso CymitQuimica, offriamo una varietà di modulatori dei canali del cloruro per supportare la tua ricerca sul trasporto ionico, l'omeostasi cellulare e i meccanismi delle malattie.
Trovati 53 prodotti di "Canale del cloruro"
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Fenamic acid
CAS:Fenamic acid (N-Phenylanthranilic acid) is a chloride channel blocker that causes renal papillary necrosis in rats.Formula:C13H11NO2Purezza:99.6%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:213.2319CaCCinh-A01
CAS:CaCCinh-A01 is an inhibitor of the calcium-activated chloride channel (CaCC, 10 μM) and TMEM16A (IC50: 2.1 μM).Formula:C18H21NO4SPurezza:99.36% - >99.99%Colore e forma:SolidPeso molecolare:347.43Talniflumate
CAS:<p>Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell</p>Formula:C21H13F3N2O4Purezza:98% - 99.81%Colore e forma:White To Pale Yellow Crystalline PowderPeso molecolare:414.33MONNA
CAS:MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.Formula:C18H14N2O5Purezza:98.29%Colore e forma:SolidPeso molecolare:338.31Lubiprostone
CAS:Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.Formula:C20H32F2O5Purezza:97.31% - 98.54%Colore e forma:White Odorless Crystals Or Crystalline PowderPeso molecolare:390.46Guanidinoethyl sulfonate
CAS:Guanidinoethyl sulfonate (Taurocyamine) is a competitive glycine receptor antagonist.Formula:C3H9N3O3SPurezza:99.43% - 99.47%Colore e forma:SolidPeso molecolare:167.19Adjudin
CAS:Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.Formula:C15H12Cl2N4OPurezza:96.51% - ≥95%Colore e forma:SolidPeso molecolare:335.19NPPB
CAS:NPPB is a chloride channel blocker with IC50 of 80 nM .Formula:C16H16N2O4Purezza:99.95%Colore e forma:Light Yellow To Yellow SolidPeso molecolare:300.31Anthracene-9-carboxylic acid
CAS:Anthracene-9-carboxylic acid is an inhibitor of chloride transport with a moderate to strong inhibitory action on PKA activated cardiac IcI.Formula:C15H10O2Purezza:99.05%Colore e forma:Yellow Cystalline PowderPeso molecolare:222.24Org 25543
CAS:Org 25543 is the development of an N-Acyl amino acid that selectively inhibits the glycine transporter 2 to produce analgesia in a rat model of chronic pain.Formula:C24H32N2O4Purezza:99.13%Colore e forma:SolidPeso molecolare:412.52Phenyl benzoate
CAS:Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid.It is an important organic synthesis intermediate.Formula:C13H10O2Purezza:99.63%Colore e forma:White Crystalline PowderPeso molecolare:198.22Selamectin
CAS:Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening inFormula:C43H63NO11Purezza:99.84%Colore e forma:SolidPeso molecolare:769.96Hydroflumethiazide
CAS:Hydroflumethiazide is a thiazide diuretic. It has also shown the activity of anti-hypertensive.Formula:C8H8F3N3O4S2Colore e forma:Crystals SolidPeso molecolare:331.29Alilusem
CAS:Alilusem is a new diuretic that is beneficial to the clinical treatment of hypertension.Formula:C17H15ClKN2O5SColore e forma:SolidPeso molecolare:433.92H100
CAS:H100 inhibits Cl- transport, mildly affects NaK2Cl cotransporter and Band 3 anion exchanger, not KCl cotransporter.Formula:C18H16N2O6SPurezza:98%Colore e forma:SolidPeso molecolare:388.4NS5818
CAS:NS5818 inhibits ClC.Formula:C23H19Cl2N7O2Purezza:98%Colore e forma:SolidPeso molecolare:496.35ANO1-IN-2
CAS:ANO1-IN-2: potent ANO1 blocker (IC50: 1.75 μM), less effective on ANO2 (IC50: 7.43 μM), inhibits glioblastoma cell growth.Formula:C16H14ClN3O2S2Colore e forma:SolidPeso molecolare:379.88BTG-1640
CAS:BTG-1640 is used potentially for the treatment of anxiety and panic disorder.Formula:C15H19NO2Colore e forma:SolidPeso molecolare:245.32Bts 39542
CAS:Bts 39542 is a diuretic that plays a major role in the Henle circulation and increases renal blood flow without affecting glomerular filtration rate.Formula:C16H11ClN4O3SColore e forma:SolidPeso molecolare:374.8IAA-94
CAS:IAA-94 is an inhibitor of chloride channels, it binds channels in bovine kidney cortex microsomes with a Ki value of 1 µM.Formula:C17H18Cl2O4Colore e forma:SolidPeso molecolare:357.23
