Ricettore CGRP
I recettori del CGRP sono coinvolti nella trasmissione del dolore e nella regolazione del flusso sanguigno. Il CGRP è un neuropeptide che svolge un ruolo cruciale nella fisiopatologia dell'emicrania dilatando i vasi sanguigni e modulando le vie di segnalazione del dolore. Il targeting dei recettori del CGRP è diventato un approccio promettente nello sviluppo di terapie per l'emicrania. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori del CGRP per supportare la tua ricerca nella gestione del dolore, neurobiologia e salute vascolare.
Trovati 53 prodotti di "Ricettore CGRP"
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Erenumab
CAS:Erenumab: human antibody blocking CGRP receptors to prevent migraines.Purezza:99.43% (SEC-HPLC) - > 95%Colore e forma:LiquidPeso molecolare:146.2 kDaPHM-27 (human) acetate
PHM-27 (human) acetate is the endogenous peptide product of prepro-VIP (human), an agonist of the calcitonin receptor (EC 50 = 11 nM). enhanced insulin secretion.
Formula:C137H215F3N34O42SPurezza:99.20%Colore e forma:SoildPeso molecolare:3099.44CRSP-1
CAS:Central CT receptor agonist, 350x stronger than CT, no CGRP or adrenomedullin action, inhibits osteoclasts, affects rat feeding, body temp, and calcium.Formula:C175H294N54O49S5Purezza:98%Colore e forma:SolidPeso molecolare:4098.88β-CGRP (mouse)
β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.Formula:C165H265N49O55S2Colore e forma:SolidPeso molecolare:3879.29Olcegepant hydrochloride
CAS:Olcegepant hydrochloride (BIBN-4096 hydrochloride) is a selective calcitonin gene-related peptide 1 (CGRP1) receptor antagonist.Formula:C38H48Br2ClN9O5Purezza:99.69%Colore e forma:SolidPeso molecolare:906.11Adrenotensin (human)
CAS:Adrenotensin: human 153-185 fragment of Adrenomedullin precursor, a 52-amino acid peptide in CGRP hormone family.Formula:C143H224N42O43Colore e forma:SolidPeso molecolare:3219.56Calcitonin Gene Related Peptide (CGRP) II, rat TFA
Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.
Formula:C165H268F3N51O52S2Colore e forma:SolidPeso molecolare:3919.33Cagrilintide acetate
.Cagrilintide is a long-acting amylin analog,treat diabetes and obesity by reducing appetite through activation of the AMY3R and calcitonin receptor.Formula:C196H316N54O61S2Purezza:99.88%Colore e forma:SolidPeso molecolare:4469.06Vazegepant
CAS:Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.Formula:C36H46N8O3Purezza:98.61% - 99.98%Colore e forma:SolidPeso molecolare:638.80Ref: TM-T38734
1mg96,00€5mg227,00€10mg335,00€25mg567,00€50mgPrezzo su richiesta100mgPrezzo su richiesta1mL*10mM (DMSO)305,00€CGRP antagonist 6
CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.Colore e forma:Odour SolidAdrenomedullin (1-50), rat
CAS:Rat adrenomedullin (1-50) is a 50-AA peptide; induces arterial vasodilation by activating CGRP1 receptors.Formula:C248H381N77O75S5Purezza:98%Colore e forma:SolidPeso molecolare:5729.5Adrenomedullin (AM) (22-52), human
CAS:Adrenomedullin (ADM) is a 52-aa hypotensive peptide. Adrenomedullin (ADM) has structural similarity with amylin.Formula:C159H252N46O48Purezza:98%Colore e forma:SolidPeso molecolare:3576.04HCGRP-(8-37)
CAS:Rat CGRP-(8-37) (VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF) is a highly selective CGRP receptor antagonistFormula:C139H230N44O38Purezza:98%Colore e forma:SolidPeso molecolare:3125.59Calcitonin (human)
CAS:Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.Formula:C151H226N40O45S3Purezza:98%Colore e forma:White Lyophilized PowderPeso molecolare:3417.87α-CGRP, rat
CAS:Endogenous neuropeptide, potent vasodilatorFormula:C162H262N50O52S2Purezza:98%Colore e forma:SolidPeso molecolare:3806.25β-CGRP, human
CAS:β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascularFormula:C162H267N51O48S3Purezza:98%Colore e forma:SolidPeso molecolare:3793.41(3R,5R,6S)-Atogepant
(3R,5R,6S)-Atogepant (MK-8031) is a CGRP antagonist enantiomer used in migraine research.Formula:C29H23F6N5O3Colore e forma:SolidPeso molecolare:603.52PHM-27 (human)
CAS:Human-derived peptide, VIP/PHM 27 analog, boosts insulin by targeting calcitonin receptor with an EC50 of 11 nM.Formula:C135H214N34O40SPurezza:98%Colore e forma:SolidPeso molecolare:2985.44Adrenomedullin (AM) (22-52), human TFA
Adrenomedullin (AM) human (22-52) is a truncated NH2 TFA-modified adrenal medullary receptor antagonist.Formula:C161H253N46F3O50Purezza:98%Colore e forma:SolidPeso molecolare:3690.06Galcanezumab
CAS:Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.Purezza:> 95%Colore e forma:LiquidPeso molecolare:144.08 kDaα-CGRP (mouse, rat) TFA
α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions andFormula:C162H262N50O52S2·C2HF3O2Purezza:98%Colore e forma:SolidAdrenomedullin (AM) (22-52), human acetate
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and anFormula:C161H256N46O50Purezza:99.42%Colore e forma:SolidPeso molecolare:3636.09Calcitonin Gene Related Peptide (CGRP) II, rat
CAS:CGRP II is a potent vasodilator that boosts pancreatic enzyme levels by activating β-cell receptors.Formula:C163H267N51O50S2Purezza:98%Colore e forma:SolidPeso molecolare:3805.31Adrenomedullin (11-50), rat
CAS:Adrenomedullin 11-50 rat is a peptide, stimulates CGRP1 receptor for vasodilation, used in bone growth research.Formula:C194H304N58O59S4Purezza:98%Colore e forma:SolidPeso molecolare:4521.17HTL22562
CAS:HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formula:C40H49N11O5Colore e forma:SolidPeso molecolare:763.904α-CGRP(human)
CAS:Endogenous calcitonin gene-related peptide receptor (CGRP) agonist.Formula:C163H267N51O49S2Purezza:98%Colore e forma:SolidPeso molecolare:3789.33Adrenomedullin (16-31), human
CAS:Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM).Formula:C82H129N25O21S2Purezza:98%Colore e forma:SolidPeso molecolare:1865.19CGRP 8-37 (rat)
CAS:CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.Formula:C138H224N42O41Purezza:99.28%Colore e forma:SolidPeso molecolare:3127.51Cagrilintide
CAS:Cagrilintide: a long-acting amylin analogue, potential obesity treatment, reduces appetite and weight.
Formula:C194H312N54O59S2Colore e forma:SolidPeso molecolare:4409.01α-CGRP(human) TFA
α-CGRP(human) TFA is a 37-amino acid regulatory neuropeptide that is extensively located within the central and peripheral nervous system, functioning as aFormula:C165H268F3N51O51S2Colore e forma:SolidPeso molecolare:3903.33Adrenomedullin (16-31), human TFA
Human adrenomedullin (16-31) TFA, fragment 16-31, binds CGRP1 receptor, raises rat blood pressure, not cats’.Formula:C84H130F3N25O23S2Colore e forma:SolidPeso molecolare:1979.21SUN B8155
CAS:SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Formula:C14H15N3O3Purezza:99.38% - 99.38%Colore e forma:SolidPeso molecolare:273.29Calcitonin (salmon)
CAS:Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.Formula:C145H240N44O48S2Purezza:99.41% - 99.80%Colore e forma:PowderPeso molecolare:3431.85Telcagepant
CAS:Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.Formula:C26H27F5N6O3Purezza:98.98% - 98.98%Colore e forma:SolidPeso molecolare:566.52Calcitonin(salmon) Acetate(47931-85-1(free base))
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5Formula:C145H240N44O48S2Purezza:99.29%Colore e forma:SolidPeso molecolare:3431.85β-CGRP, human acetate
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptorFormula:C164H271N51O50S3Purezza:99.35%Colore e forma:SolidPeso molecolare:3853.46Rimegepant
CAS:View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.Formula:C28H28F2N6O3Purezza:99.1% - 99.99%Colore e forma:SolidPeso molecolare:534.56BCTC
CAS:BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)Formula:C20H25ClN4OPurezza:99.21%Colore e forma:SolidPeso molecolare:372.89Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Formula:C36H47ClN8O3Purezza:98.93%Colore e forma:SolidPeso molecolare:675.3Ref: TM-T8682
1mg107,00€5mg227,00€10mg334,00€25mg565,00€50mg805,00€100mg1.111,00€1mL*10mM (DMSO)329,00€Olcegepant
CAS:Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4Formula:C38H47Br2N9O5Purezza:96.08% - 97.24%Colore e forma:SolidPeso molecolare:869.65HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.Formula:C141H234N44O40Purezza:99.29%Colore e forma:SolidPeso molecolare:3185.64Atogepant
CAS:Atogepant (MK-8031) is an orally available, selective and potent calcitonin gene-related peptide receptor (CGRP) antagonist for the study of migraine.Formula:C29H23F6N5O3Purezza:99.66%Colore e forma:SolidPeso molecolare:603.52Ref: TM-T26682
1mg147,00€5mg250,00€10mg313,00€25mg620,00€50mg1.108,00€100mg1.611,00€200mg2.178,00€1mL*10mM (DMSO)334,00€Eptinezumab
CAS:Eptinezumab is a humanised monoclonal antibody targeting CGRP (calcitonin gene-related peptide), which prevents CGRP binding to its receptor, migraine.
Purezza:95% - 95%Colore e forma:LiquidSB 268262
CAS:CGRP1 antagonistFormula:C18H15N3O4S2Purezza:98%Colore e forma:SolidPeso molecolare:401.46CGRP antagonist 1
CAS:CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for theFormula:C29H26N4O4Purezza:99.55%Colore e forma:SolidPeso molecolare:494.54Ubrogepant
CAS:Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formula:C29H26F3N5O3Purezza:99.452% - 99.78%Colore e forma:SolidPeso molecolare:549.54Ref: TM-T17194
1mg153,00€5mg378,00€10mg597,00€25mg929,00€50mg1.225,00€100mg1.681,00€1mL*10mM (DMSO)455,00€CGRP antagonist 7
CAS:CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.Formula:C30H32FN5O3Colore e forma:SolidPeso molecolare:529.61Rimegepant sulfate hydrate
CAS:Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.Formula:C56H64F4N12O13SColore e forma:SolidPeso molecolare:1221.2526DNA crosslinker 6
CAS:DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.Formula:C19H21N7OColore e forma:SolidPeso molecolare:363.42MK-3207 Hydrochloride
CAS:MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.Formula:C31H30ClF2N5O3Purezza:98.19%Colore e forma:SolidPeso molecolare:594.05MK-3207
CAS:MK-3207 is a potent, oral CGRP receptor antagonist with high selectivity for human and monkey receptors, inhibiting blood flow in vivo.Formula:C31H29F2N5O3Colore e forma:SolidPeso molecolare:557.59MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Formula:C31H30F2N6O3Colore e forma:SolidPeso molecolare:572.61BI-44370
CAS:BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formula:C35H47N5O6Colore e forma:SolidPeso molecolare:633.78
