Ricettore CGRP
I recettori del CGRP sono coinvolti nella trasmissione del dolore e nella regolazione del flusso sanguigno. Il CGRP è un neuropeptide che svolge un ruolo cruciale nella fisiopatologia dell'emicrania dilatando i vasi sanguigni e modulando le vie di segnalazione del dolore. Il targeting dei recettori del CGRP è diventato un approccio promettente nello sviluppo di terapie per l'emicrania. Presso CymitQuimica, offriamo una gamma di modulatori dei recettori del CGRP per supportare la tua ricerca nella gestione del dolore, neurobiologia e salute vascolare.
Trovati 55 prodotti per "Ricettore CGRP".
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Vazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Formula:C36H47ClN8O3Purezza:98.93%Colore e forma:White SolidPeso molecolare:675.3Calcitonin(salmon) Acetate(47931-85-1(free base))
Calcitonin(salmon)Acetate(47931-85-1(free base))(Salmon calcitonin) , a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5Formula:C147H243N44O50S2Purezza:99.29% - 99.63%Colore e forma:White SolidPeso molecolare:3490.94HCGRP-(8-37) acetate
HCGRP-(8-37) acetate is a human calcitonin gene-related peptide (hCGRP) fragment acetate and also an antagonist of CGRP receptor.Formula:C141H234N44O40Purezza:99.53%Colore e forma:SolidPeso molecolare:3185.64Atogepant
CAS:Atogepant (MK-8031) is an orally available, selective and potent calcitonin gene-related peptide receptor (CGRP) antagonist for the study of migraine.Formula:C29H23F6N5O3Purezza:99.66%Colore e forma:SolidPeso molecolare:603.52Ref: TM-T26682
1mg147,00€5mg250,00€10mg313,00€1mL*10mM (DMSO)334,00€25mg620,00€50mg1.108,00€100mg1.611,00€200mg2.178,00€Eptinezumab
CAS:Eptinezumab is a humanised monoclonal antibody targeting CGRP (calcitonin gene-related peptide), which prevents CGRP binding to its receptor, migraine.Purezza:95% - 96.9% (SDS-PAGE); 99.8% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:143.27 kDaFremanezumab
CAS:Fremanezumab (TEV-48125) is a humanised monoclonal antibody targeting CGRP, capable of neutralising human, mouse and rat CGRP, migraine.Purezza:95% - 97.6% (SDS-PAGE); 95.9% (SEC-HPLC)Colore e forma:Transparent LiquidPeso molecolare:145.49 kDaSB 268262
CAS:CGRP1 antagonistFormula:C18H15N3O4S2Purezza:98%Colore e forma:SolidPeso molecolare:401.46CGRP antagonist 1
CAS:CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for theFormula:C29H26N4O4Purezza:99.55%Colore e forma:SolidPeso molecolare:494.54Ubrogepant
CAS:Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Formula:C29H26F3N5O3Purezza:99.45% - 99.78%Colore e forma:Yellow SolidPeso molecolare:549.54Ref: TM-T17194
1mg144,00€5mg358,00€1mL*10mM (DMSO)432,00€10mg565,00€25mg880,00€50mg1.161,00€100mg1.594,00€Rimegepant sulfate hydrate
CAS:Rimegepant (BMS-927711/BHV-3000): oral CGRP blocker for migraines, effective without vasoconstriction, beats placebo, well-tolerated.Formula:C56H64F4N12O13SColore e forma:SolidPeso molecolare:1221.2526CGRP antagonist 7
CAS:CGRP antagonist 7 is a potent calcitonin gene-related peptide receptor (CGRP) antagonist with a Ki value of 0.029 nM. It effectively inhibits CGRP receptor-mediated cyclic adenosine monophosphate (cAMP) production, with an IC50 value of 1.5 nM. This compound is useful in migraine research.Formula:C30H32FN5O3Colore e forma:SolidPeso molecolare:529.61BI-44370
CAS:BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.Formula:C35H47N5O6Colore e forma:SolidPeso molecolare:633.78HTL22562
CAS:HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formula:C40H49N11O5Colore e forma:SolidPeso molecolare:763.904MK-3207 Hydrochloride
CAS:MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.Formula:C31H30ClF2N5O3Purezza:98.19%Colore e forma:Yellow SolidPeso molecolare:594.05DNA crosslinker 6
CAS:DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.Formula:C19H21N7OColore e forma:SolidPeso molecolare:363.42
