Canale del sodio
I canali del sodio sono proteine di membrana essenziali che permettono il passaggio degli ioni sodio (Na+) attraverso la membrana cellulare, generando e propagando segnali elettrici nei neuroni, nelle cellule muscolari e in altri tessuti eccitabili. Questi canali sono vitali per l'inizio e la conduzione dei potenziali d'azione, rendendoli cruciali in processi come la trasmissione degli impulsi nervosi, la contrazione muscolare e la funzione cardiaca. La disregolazione dei canali del sodio può portare a disturbi neurologici, aritmie e condizioni di dolore cronico. Presso CymitQuimica, offriamo una varietà di modulatori dei canali del sodio per supportare la tua ricerca in neurobiologia, cardiologia e gestione del dolore.
Trovati 210 prodotti di "Canale del sodio"
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Evenamide
CAS:Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.Formula:C16H26N2O2Purezza:96.74% - 99.15%Colore e forma:SolidPeso molecolare:278.39Ref: TM-T15260
1mg42,00€5mg88,00€10mg127,00€25mg250,00€50mg399,00€100mg645,00€200mg898,00€1mL*10mM (DMSO)87,00€Metaflumizone
CAS:Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.Formula:C24H16F6N4O2Purezza:98.73%Colore e forma:SolidPeso molecolare:506.40Cyfluthrin
CAS:Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pestsFormula:C22H18Cl2FNO3Purezza:99.76%Colore e forma:SolidPeso molecolare:434.29A-803467
CAS:A-803467 is a selective NaV1.8 channel blocker.Formula:C19H16ClNO4Purezza:96.94% - 98%Colore e forma:SolidPeso molecolare:357.79Metergoline
CAS:Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.Formula:C25H29N3O2Purezza:99.83% - 99.97%Colore e forma:SolidPeso molecolare:403.52Tenapanor
CAS:Tenapanor (RDX 5791), an NHE3 inhibitor, regulates sodium in the gut and kidney with a strong preclinical safety record and minimal side effects.Formula:C50H66Cl4N8O10S2Purezza:99.49% - 99.85%Colore e forma:SolidPeso molecolare:1145.05QX-222 chloride
CAS:QX-222 chloride (Lidocaine N-Methyl Hydrochloride) is a sodium channel blocker.Formula:C13H21ClN2OPurezza:97.37%Colore e forma:SolidPeso molecolare:256.77Eslicarbazepine Acetate
CAS:Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.Formula:C17H16N2O3Purezza:99.58% - >99.99%Colore e forma:White To Off-White SolidPeso molecolare:296.32Ref: TM-T3285
5mg38,00€10mg50,00€25mg92,00€50mg124,00€100mg170,00€200mg268,00€500mg393,00€1mL*10mM (DMSO)55,00€Nicainoprol
CAS:Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.Formula:C21H27N3O3Purezza:99.54%Colore e forma:SolidPeso molecolare:369.46Ref: TM-T4539
1mg140,00€5mg344,00€10mg512,00€25mg812,00€50mg1.093,00€100mg1.473,00€1mL*10mM (DMSO)350,00€Sodium ionophore III
CAS:Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.Formula:C34H52N2O4Purezza:99.51% - 99.78%Colore e forma:SolidPeso molecolare:552.79BI 01383298
CAS:BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).Formula:C19H19Cl2FN2O3SPurezza:99.71%Colore e forma:SolidPeso molecolare:445.34Ranolazine
CAS:Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.Formula:C24H33N3O4Purezza:98.13%Colore e forma:White SolidPeso molecolare:427.54Nav1.8-IN-1
CAS:<p>Nav1.8-IN-1 (CHEMBL1270208) is an inhibitor of human NaV1.8</p>Formula:C20H15ClF3N3O2Purezza:97.59%Colore e forma:SolidPeso molecolare:421.8GS967
CAS:<p>GS967 is a potent, and selective inhibitor of cardiac late sodium current (late INa ).</p>Formula:C14H7F6N3OPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:347.22Ref: TM-T2049
2mg35,00€5mg52,00€10mg79,00€25mg159,00€50mg284,00€100mg495,00€200mg718,00€500mg1.111,00€Pilsicainide HCl
CAS:Pilsicainide HCl (SUN 1165) is a pure sodium channel blockerFormula:C17H25ClN2OPurezza:99.01% - 99.80%Colore e forma:SolidPeso molecolare:308.85AZ194
CAS:CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.Formula:C34H31F2N3O3Purezza:99.61%Colore e forma:SolidPeso molecolare:567.62Ref: TM-T9461
1mg77,00€5mg166,00€10mg260,00€25mg485,00€50mg700,00€100mg982,00€500mg1.963,00€1mL*10mM (DMSO)178,00€Licarbazepine
CAS:<p>Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial</p>Formula:C15H14N2O2Purezza:99.11%Colore e forma:SolidPeso molecolare:254.28Rimeporide hydrochloride
CAS:Rimeporide hydrochloride (EMD-87580 hydrochloride) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.Formula:C11H16ClN3O5S2Purezza:99.82%Colore e forma:SolidPeso molecolare:369.84Cariporide
CAS:Cariporide (HOE-642), an NHE1 inhibitor, reduces human platelet degranulation, platelet-leukocyte aggregates, and GPIIb/IIIa activation.Formula:C12H17N3O3SPurezza:95.4% - 99.88%Colore e forma:SolidPeso molecolare:283.35DS-1971a
CAS:DS-1971a is a highly potent and selective NaV1.7 inhibitor. DS-1971a exhibits a favorable toxicological profile and analgesic effects.Formula:C20H21ClFN5O3SPurezza:99.66%Colore e forma:SolidPeso molecolare:465.93RY785
CAS:RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.Formula:C21H20N4O2SPurezza:99.78%Colore e forma:SolidPeso molecolare:392.47Ref: TM-T12786
1mg51,00€5mg144,00€10mg235,00€25mg399,00€50mg560,00€100mg787,00€200mg1.093,00€1mL*10mM (DMSO)125,00€Fosphenytoin disodium
CAS:Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blockerFormula:C16H13N2Na2O6PPurezza:99.97%Colore e forma:White Crystalline PowderPeso molecolare:406.24Flecainide acetate
CAS:Flecainide acetate (R-818) is a class Ic antiarrhythmic agent used to prevent and treat tachyarrhythmias (abnormal fast rhythms of the heart).Formula:C19H24F6N2O5Purezza:99.42%Colore e forma:SolidPeso molecolare:474.396-Benzoylheteratisine
CAS:6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid.Formula:C29H37NO6Purezza:99.87%Colore e forma:SolidPeso molecolare:495.61GNE-131
CAS:GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).Formula:C23H30N4O3SPurezza:98.54% - 99.59%Colore e forma:SolidPeso molecolare:442.57Ref: TM-TQ0014
1mg111,00€5mg264,00€10mg376,00€25mg630,00€50mg880,00€100mg1.169,00€1mL*10mM (DMSO)283,00€Benzonatate
CAS:Benzonatate is an antagonist of sodium channel protein.Formula:C30H53NO11Purezza:99.92%Colore e forma:Colorless To Faintly Yellow Oil LiquidPeso molecolare:603.74PF-06869206
CAS:PF-06869206 is an oral selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1, IC50: 380 nM).Formula:C15H14ClF3N4O2Purezza:99.79% - 99.88%Colore e forma:SolidPeso molecolare:374.75Ref: TM-TQ0011
5mg39,00€10mg64,00€25mg125,00€50mg210,00€100mgPrezzo su richiesta1mL*10mM (DMSO)35,00€Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formula:C18H28N2O·HClPurezza:99.74%Colore e forma:White Crystalline PowderPeso molecolare:324.893-Deoxyaconitine
CAS:3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thusFormula:C34H47NO10Purezza:98.31%Colore e forma:SolidPeso molecolare:629.74Ralfinamide
CAS:Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.Formula:C17H19FN2O2Purezza:99.41%Colore e forma:SolidPeso molecolare:302.34Rimeporide
CAS:Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.Formula:C11H15N3O5S2Purezza:97.66%Colore e forma:SolidPeso molecolare:333.38Ref: TM-T5319
1mg46,00€2mg62,00€5mg90,00€10mg166,00€25mg358,00€50mg523,00€100mg747,00€1mL*10mM (DMSO)108,00€Ropivacaine hydrochloride monohydrate
CAS:Ropivacaine hydrochloride monohydrate (LEA-103 HCl) is an anaesthetic agent and blocks impulse conduction through inhibiting sodium ion influx reversibly.Formula:C17H29ClN2O2Purezza:99.94% - 99.95%Colore e forma:White SolidPeso molecolare:328.88Flecainide hydrochloride
CAS:Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.Formula:C17H21ClF6N2O3Purezza:97.79%Colore e forma:SolidPeso molecolare:450.81λ-Cyhalothrin
CAS:λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group.Formula:C23H19ClF3NO3Purezza:99.76%Colore e forma:SolidPeso molecolare:449.85Raxatrigine
CAS:Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.Formula:C18H19FN2O2Purezza:98% - 99.43%Colore e forma:SolidPeso molecolare:314.35N-Me-aminopyrimidinone9
CAS:N-Me-aminopyrimidinone9 is a sodium channel antagonistFormula:C16H21N3OSPurezza:99.21%Colore e forma:SolidPeso molecolare:303.42Ref: TM-T8444
1mg62,00€5mg123,00€10mg180,00€25mg298,00€50mg419,00€100mg567,00€200mg752,00€1mL*10mM (DMSO)123,00€Levobupivacaine
CAS:Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.Formula:C18H28N2OPurezza:99.72%Colore e forma:SolidPeso molecolare:288.43Ref: TM-T1787
5mg48,00€10mg63,00€25mg93,00€50mg136,00€100mg188,00€200mg283,00€500mg487,00€1mL*10mM (DMSO)49,00€Carbamazepine
CAS:Carbamazepine: a tricyclic with anticonvulsant and analgesic effects, treats trigeminal neuralgia.Formula:C15H12N2OPurezza:99.78% - 99.79%Colore e forma:SolidPeso molecolare:236.27Propafenone hydrochloride
CAS:Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.Formula:C21H27NO3·HClPurezza:99.67%Colore e forma:White SolidPeso molecolare:377.9Benzocaine xHCl(94-09-7(free base))
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).Formula:C9H11NO2·xHClPurezza:99.37%Colore e forma:SolidPeso molecolare:N/AVX-150
CAS:VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).Formula:C21H17F4N2O7PPurezza:97.58%Colore e forma:SolidPeso molecolare:516.34Ref: TM-T9683
1mg66,00€5mg144,00€10mg235,00€25mg472,00€50mg755,00€100mg1.206,00€1mL*10mM (DMSO)164,00€PF-01247324
CAS:PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).Formula:C13H10Cl3N3OPurezza:99.22%Colore e forma:SolidPeso molecolare:330.6PF 05089771
CAS:PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.Formula:C18H12Cl2FN5O3S2Purezza:99.03% - 99.42%Colore e forma:SolidPeso molecolare:500.35Ref: TM-T7502L
1mg67,00€5mg145,00€10mg187,00€25mg309,00€50mgPrezzo su richiesta1mL*10mM (DMSO)164,00€PF-05186462
CAS:PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.Formula:C19H10ClF4N5O3S2Purezza:99.10% - 99.37%Colore e forma:SolidPeso molecolare:531.89N-Formylguanidine
CAS:Prodotto controllatoFormula:C2H5N3OColore e forma:Off-WhitePeso molecolare:87.081Benzocaine N-Glucoside (a/b mixture)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.<br>References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);<br></p>Formula:C15H21NO7Colore e forma:NeatPeso molecolare:327.33Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Formula:C8H5F3N2OSPurezza:99.71% - 99.88%Colore e forma:PowderPeso molecolare:234.2Propoxycaine hydrochloride
CAS:Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.Formula:C16H27ClN2O3Purezza:97.25%Colore e forma:SolidPeso molecolare:330.85Propafenone-d5 HCl
CAS:Propafenone-d5 HCl is a deuterated compound of Propafenone HCl. Propafenone HCl has a CAS number of 34183-22-7. Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.Formula:C21H23D5ClNO3Peso molecolare:382.9410,11-Dihydro-10-hydroxy Carbamazepine-d4
CAS:10,11-Dihydro-10-hydroxy Carbamazepine-d4 is a deuterated compound of 10,11-Dihydro-10-hydroxy Carbamazepine. 10,11-Dihydro-10-hydroxy Carbamazepine has a CAS number of 29331-92-8. Licarbazepine is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.Formula:C15H10D4N2O2Peso molecolare:258.31
