Canale del sodio
I canali del sodio sono proteine di membrana essenziali che permettono il passaggio degli ioni sodio (Na+) attraverso la membrana cellulare, generando e propagando segnali elettrici nei neuroni, nelle cellule muscolari e in altri tessuti eccitabili. Questi canali sono vitali per l'inizio e la conduzione dei potenziali d'azione, rendendoli cruciali in processi come la trasmissione degli impulsi nervosi, la contrazione muscolare e la funzione cardiaca. La disregolazione dei canali del sodio può portare a disturbi neurologici, aritmie e condizioni di dolore cronico. Presso CymitQuimica, offriamo una varietà di modulatori dei canali del sodio per supportare la tua ricerca in neurobiologia, cardiologia e gestione del dolore.
Trovati 367 prodotti per "Canale del sodio".
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Benzonatate (PEGn)
CAS:Benzonatate (PEGn) is a unique non-narcotic cough suppressant featuring sodium channel blocking properties and anesthetic effects on respiratory tract stretch receptors.Formula:(C2H4O)nC12H17NO2Colore e forma:SolidAnthopleurin-A
CAS:Anthopleurin-A, a sodium channel toxin, is selective for cardiac channels and has a cardiotonic effect. It can be isolated from the sea anemone [1] [2].Formula:C220H326N64O67S6Colore e forma:SolidPeso molecolare:5131.72Solpecainol
CAS:solpecainol is a sodium channel blocker used in the study of neurological and cardiovascular diseases.Formula:C18H23NO3Purezza:99.71%Colore e forma:White OilPeso molecolare:301.381-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.Formula:C6H8N2OPurezza:99.92%Colore e forma:SolidPeso molecolare:124.1405GpTx-1
CAS:GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].Formula:C176H271N53O45S7Purezza:98%Colore e forma:SolidPeso molecolare:4073.82Batrachotoxin
CAS:Batrachotoxin (BTX), a potent neurotoxin and cardiotoxin, is found in the skin of the Colombian dart frog (Phyllobates aurotaenia). As an activator of sodium channels (sodium channel), it interferes with normal sodium channel closure by binding to voltage-gated sodium channels (sodium channel) on the cell membrane. This interaction causes a continuous influx of sodium ions into the cells, leading to persistent depolarization.Formula:C31H42N2O6Colore e forma:SolidPeso molecolare:538.67Trapencaine
CAS:Trapencaine is a newly synthesized carbamate type local anesthetic that induces conformational changes in sodium channels on hypertrophic cell membranes.Formula:C22H34N2O3Purezza:97.68%Colore e forma:SolidPeso molecolare:374.52XPC-7724
XPC-7724 is a selective inhibitor of the Nav1.6 channel, with an IC50 value of 0.078 μM. It is useful in research related to neurological disorders.Formula:C25H30FN5O2SPeso molecolare:483.21042Zoniporide
CAS:Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits platelet swelling and can be used in the study of cardiovascular diseases.Formula:C17H16N6OPurezza:99.78%Colore e forma:SolidPeso molecolare:320.35Nav1.2-IN-2
CAS:Nav1.2-IN-2 is a Nav1.2 inhibitor, IC₅₀=0.18 μM for inactivated Nav1.2, inhibits Veratridine-induced calcium influx, epilepsy.Formula:C17H26N2O4Purezza:99.97%Colore e forma:White SolidPeso molecolare:322.4LTGO-33
CAS:LTGO-33 is a voltage-gated sodium channel NaV1.8 inhibitor that inhibits NaV1.8, NaV1.1-NaV1.7, and NaV1.9.Formula:C21H17F4N3O3SPurezza:97.6%Colore e forma:White SolidPeso molecolare:467.44Nav1.8-IN-6
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor with IC50 values of 513.33 nM in the resting state and 471.81 nM in the partially activated state. Nav1.8-IN-6 also exhibits analgesic activity.Formula:C19H17F6N3O2Colore e forma:SolidPeso molecolare:433.1225Sodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Formula:C24H23F3N4O2Colore e forma:SolidPeso molecolare:456.17731Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7400
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiestaGrTx1
GrTx1, a peptide toxin derived from Grammostola rosea spider venom, selectively inhibits sodium channels Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6, and Nav1.7,Formula:C159H243N45O41S8Purezza:98%Colore e forma:SolidPeso molecolare:3697.43Pterinotoxin-1
Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].Formula:C163H251N49O53S7Purezza:98%Colore e forma:SolidPeso molecolare:3969.49Ion Channel Targeted Library
A unique collection of xnum compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;Colore e forma:Odour SolidRef: TM-L2300
1mgPrezzo su richiesta10μL*10mM (DMSO)Prezzo su richiesta20μL*10mM (DMSO)Prezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaTap1a
Theraphotoxin-Tap1a (Tap1a) is a spider venom-derived peptide that acts as an inhibitor of sodium channels, displaying IC50 values of 80 nM for Na v 1.7 and 301Formula:C174H258N52O55S7Purezza:98%Colore e forma:SolidPeso molecolare:4182.68GX 201
CAS:GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.Formula:C25H27ClF4N2O4SPurezza:99.81%Colore e forma:White SolidPeso molecolare:563Ref: TM-T9647
1mL*10mM (DMSO)Prezzo su richiesta1mg100,00€5mg236,00€10mg358,00€25mg595,00€50mg858,00€100mg1.189,00€Phlotoxin-1 TFA
Phlotoxin-1 (PhlTx1) is a 34-amino acid polypeptide with three disulfide bonds. It is derived from spiders of the Phlogiellus genus. Phlotoxin-1 acts as an antinociceptive agent by inhibiting the NaV1.7 channel.Colore e forma:Odour Solid
