Canale del sodio
I canali del sodio sono proteine di membrana essenziali che permettono il passaggio degli ioni sodio (Na+) attraverso la membrana cellulare, generando e propagando segnali elettrici nei neuroni, nelle cellule muscolari e in altri tessuti eccitabili. Questi canali sono vitali per l'inizio e la conduzione dei potenziali d'azione, rendendoli cruciali in processi come la trasmissione degli impulsi nervosi, la contrazione muscolare e la funzione cardiaca. La disregolazione dei canali del sodio può portare a disturbi neurologici, aritmie e condizioni di dolore cronico. Presso CymitQuimica, offriamo una varietà di modulatori dei canali del sodio per supportare la tua ricerca in neurobiologia, cardiologia e gestione del dolore.
Trovati 209 prodotti di "Canale del sodio"
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Levobupivacaine hydrochloride
CAS:Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.Formula:C18H28N2O·HClPurezza:99.74%Colore e forma:White Crystalline PowderPeso molecolare:324.893-Deoxyaconitine
CAS:3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thusFormula:C34H47NO10Purezza:98.31%Colore e forma:SolidPeso molecolare:629.74Ralfinamide
CAS:Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.Formula:C17H19FN2O2Purezza:99.41%Colore e forma:SolidPeso molecolare:302.34Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Formula:C8H5F3N2OSPurezza:99.71% - 99.88%Colore e forma:PowderPeso molecolare:234.2Benzocaine N-Glucoside (a/b mixture)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.<br>References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);<br></p>Formula:C15H21NO7Colore e forma:NeatPeso molecolare:327.33Propoxycaine hydrochloride
CAS:Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.Formula:C16H27ClN2O3Purezza:97.25%Colore e forma:SolidPeso molecolare:330.85N-Formylguanidine
CAS:Prodotto controllatoFormula:C2H5N3OColore e forma:Off-WhitePeso molecolare:87.08110,11-Dihydro-10-hydroxy Carbamazepine-d4
CAS:10,11-Dihydro-10-hydroxy Carbamazepine-d4 is a deuterated compound of 10,11-Dihydro-10-hydroxy Carbamazepine. 10,11-Dihydro-10-hydroxy Carbamazepine has a CAS number of 29331-92-8. Licarbazepine is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders.Formula:C15H10D4N2O2Peso molecolare:258.31Propafenone-d5 HCl
CAS:Propafenone-d5 HCl is a deuterated compound of Propafenone HCl. Propafenone HCl has a CAS number of 34183-22-7. Propafenone HCl is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias.Formula:C21H23D5ClNO3Peso molecolare:382.94N-(Chloroacetyl)-2,5-dimethylaniline
CAS:Prodotto controllato<p>Applications N-(Chloroacetyl)-2,5-dimethylaniline is an intermediate in the synthesis of impurities of Lidocaine (L397800), an anesthetic local agent and antiarrythmic class IB agent.<br>References Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),<br></p>Formula:C10H12ClNOColore e forma:NeatPeso molecolare:197.66Deacetamide Acetonitrile-pentisomide
CAS:Prodotto controllato<p>Applications Deacetamide Acetonitrile-pentisomide is an intermediate in the synthesis of Pentisomide (P275600). Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).<br>References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992); Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)<br></p>Formula:C19H31N3Colore e forma:NeatPeso molecolare:301.473-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
CAS:Prodotto controllato<p>Applications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.<br>References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)<br></p>Formula:C10H12ClNO3SColore e forma:NeatPeso molecolare:261.73Propafenone D7 hydrochloride
CAS:Propafenone D7 hydrochloride is the deuterium labeled Propafenone, and is a classic anti-arrhythmic medication.Formula:C21H28ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:384.95Methocarbamol D5
CAS:Methocarbamol is a central muscle relaxant. Methocarbamol D5 is deuterium labeled Methocarbamol.Formula:C11H15NO5Purezza:98%Colore e forma:SolidPeso molecolare:246.27Nav1.8-IN-14
CAS:Nav1.8-IN-14 (compound 20) is an effective selective inhibitor of Nav1.8. It is utilized in the research of pain-associated diseases.Formula:C18H17F5N4O3SPeso molecolare:464.416-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)hexanamide
Prodotto controllato<p>Applications 6-(Propylamino)-2-hydroxy-N-(2,6-dimethylphenyl)-hexanamide is a derivative of Bupivacaine (B689560), a sodium channel blocker, local anesthetic.<br>References Wilson, T.D., et al.: Anal. Profiles Drug Subs., 19, 59 (1990), McClellan, K.J., et al.: Drugs, 56, 355 (1998),<br></p>Formula:C17H28N2O2Colore e forma:NeatPeso molecolare:292.4163-Deoxyyunaconitine
CAS:Prodotto controllato<p>Applications 3-Deoxyyunaconitine is a metabolite of Aconitine (A189875), a neurotoxin that binds, activates tetrodotoxin-sensitive Na+ channels and prolongs the opening of the sodium-ion channel by suppressing conformational changes.<br>References Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),<br></p>Formula:C35H49NO10Colore e forma:NeatPeso molecolare:643.761,2,4-Oxadiazol-3-amine
CAS:Prodotto controllato<p>Applications 1,2,4-oxadiazol-3-amine (cas# 39512-64-6) is a useful research chemical.<br></p>Formula:C2H3N3OColore e forma:NeatPeso molecolare:85.06Halofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purezza:99.53%Colore e forma:Off-White SolidPeso molecolare:414.68Clopamide
CAS:Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.Formula:C14H20ClN3O3SPurezza:99.71%Colore e forma:White To Yellowish Crystalline PowderPeso molecolare:345.84
