Canale del calcio
I canali del calcio sono proteine di membrana che regolano il flusso di ioni calcio dentro e fuori dalle cellule, essenziale per varie funzioni cellulari, tra cui la contrazione muscolare, il rilascio di neurotrasmettitori e l'espressione genica. La disfunzione dell'attività dei canali del calcio è associata a condizioni come ipertensione, aritmie cardiache e disturbi neurologici. Presso CymitQuimica, offriamo un'ampia selezione di modulatori dei canali del calcio per supportare la tua ricerca in salute cardiovascolare, neurobiologia e trasduzione del segnale.
Trovati 525 prodotti di "Canale del calcio"
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Cav 3.2 inhibitor 3
Cav 3.2 inhibitor 3 is a potent inhibitor of the Cav3.2 T-type Ca2+channel (IC50: 0.1534 μM) and has a low binding affinity for D2 receptors.Formula:C32H37N3O2Colore e forma:SolidPeso molecolare:495.66SB-423557
CAS:SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFormula:C28H36N2O4Purezza:98%Colore e forma:SolidPeso molecolare:464.60Emopamil
CAS:Emopamil, a calcium channel inhibitor, reduces neuronal damage caused by ischemia.Formula:C23H30N2Colore e forma:SolidPeso molecolare:334.5SR 33805 oxalate
CAS:Ca2+ channel antagonistFormula:C34H42N2O9SPurezza:98%Colore e forma:SolidPeso molecolare:654.77RWJ 22108
CAS:<p>RWJ 22108 is a bronchial-selective calcium channel (calcium channel) blocker that exhibits an IC50 of 5.7 nM in dog bronchial smooth muscle calcium-dependent contractions.</p>Formula:C27H30ClFN2O4SColore e forma:SolidPeso molecolare:533.06CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFormula:C26H28Cl2N6OPurezza:98%Colore e forma:SolidPeso molecolare:511.45Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Formula:C32H37F2N3OColore e forma:SolidPeso molecolare:517.65Sesamodil
CAS:<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Formula:C29H32N2O6SPurezza:98.58% - 99.01%Colore e forma:SolidPeso molecolare:536.64Cav 3.2 inhibitor 1
<p>Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.</p>Formula:C32H39N3OColore e forma:SolidPeso molecolare:481.67Mibefradil
CAS:<p>Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).</p>Formula:C29H38FN3O3Purezza:98%Colore e forma:SolidPeso molecolare:495.63MP-010
CAS:<p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>Formula:C14H20N4O2SColore e forma:SolidPeso molecolare:308.399PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formula:C33H33N3O4Colore e forma:SolidPeso molecolare:535.63(rel)-Mirogabalin
CAS:(rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.Formula:C12H19NO2Colore e forma:SolidPeso molecolare:209.28T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formula:C36H39FN4OSColore e forma:SolidPeso molecolare:594.78Mibefradil dihydrochloride hydrate
CAS:<p>Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.</p>Formula:C29H42Cl2FN3O4Colore e forma:SolidPeso molecolare:586.57IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Formula:C15H14F3NO2Colore e forma:SolidPeso molecolare:297.27TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Formula:C19H27Cl2FN2OColore e forma:SolidPeso molecolare:389.33PD-217014
CAS:<p>PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.</p>Formula:C10H17NO2Colore e forma:SolidPeso molecolare:183.25IAA65
CAS:<p>IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].</p>Formula:C16H13F6NO2Colore e forma:SolidPeso molecolare:365.27CAD204520
CAS:CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).Formula:C23H32F3N3O2Colore e forma:SolidPeso molecolare:439.51NNC 55-0396
CAS:<p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>Formula:C30H40Cl2FN3O2Purezza:99.00%Colore e forma:SolidPeso molecolare:564.56Leualacin
CAS:Leualacin is a novel calcium blocker from Hapsidospora irregularis.Formula:C31H47N3O7Purezza:98%Colore e forma:SolidPeso molecolare:573.72Verapamil EP Impurity C hydrochloride
CAS:<p>NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.</p>Formula:C12H20ClNO2Colore e forma:SolidPeso molecolare:245.75(Rac)-PD0299685
CAS:<p>(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.</p>Formula:C10H21NO2Purezza:97.20%Colore e forma:SolidPeso molecolare:187.28Fostedil
CAS:Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Formula:C18H20NO3PSPurezza:98%Colore e forma:SolidPeso molecolare:361.4Ref: TM-T27351
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