Canale del calcio
I canali del calcio sono proteine di membrana che regolano il flusso di ioni calcio dentro e fuori dalle cellule, essenziale per varie funzioni cellulari, tra cui la contrazione muscolare, il rilascio di neurotrasmettitori e l'espressione genica. La disfunzione dell'attività dei canali del calcio è associata a condizioni come ipertensione, aritmie cardiache e disturbi neurologici. Presso CymitQuimica, offriamo un'ampia selezione di modulatori dei canali del calcio per supportare la tua ricerca in salute cardiovascolare, neurobiologia e trasduzione del segnale.
Trovati 543 prodotti di "Canale del calcio"
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Oxodipine
CAS:Oxodipine blocks rabbit aortic contraction and weakens rat cardiac force; reduces Ca currents in myocytes; side effects: mouse constipation, dog gum swelling.Formula:C19H21NO6Purezza:99.64%Colore e forma:SolidPeso molecolare:359.37Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Formula:C110H196N40O24S4Purezza:98%Colore e forma:SolidPeso molecolare:2591.25γ-Glutamylserine TFA
γ-Glutamylserine TFA (γ-Glu-Ser TFA) serves as a calcium receptor activator and is utilized in research focused on Parkinson's disease, diabetes, and obesity [1Formula:C10H15F3N2O8Purezza:98%Colore e forma:SoildPeso molecolare:348.23DMNPE-4 AM-caged-calcium
CAS:DMNPE-4 AM is an EGTA analogue, Ca2+-selective, with Kd 48 nM (pH 7.2) and 19 nM (pH 7.4). Photolysis reduces its Ca2+ affinity to ~2 nM.Formula:C34H47N3O22Colore e forma:SolidPeso molecolare:849.749OPC 8490 free base
CAS:OPC 8490 free base is a positive inotropic vasodilator and a cardiotonic agent that can be used to study cardiovascular diseases.Formula:C24H27N3O3Purezza:99.53%Colore e forma:SoildPeso molecolare:405.49(R)-IDHP
CAS:(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.Formula:C12H16O5Colore e forma:SolidPeso molecolare:240.25CALP3
CAS:Cell-permeable CaM agonist, binds EF-hand, activates phosphodiesterase without Ca2+, inhibits Ca2+ toxicity, IC50=33μM.Formula:C44H68N10O9Purezza:98%Colore e forma:SolidPeso molecolare:881.08D-myo-Inositol-1,4,5-triphosphate tripotassium
CAS:D-myo-Inositol-1,4,5-triphosphate tripotassium is a second messenger in the intracellular signaling system that induces Ca2+ mobilization.Formula:C6H12K3O15P3Colore e forma:SolidPeso molecolare:534.37D-myo-Inositol-1,4,5-triphosphate trisodium
CAS:D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by phospholipase C-mediatedFormula:C6H15Na3O15P3Purezza:98%Colore e forma:SolidPeso molecolare:489.06GTx1-15
GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3Formula:C176H271N53O45S7Purezza:98%Colore e forma:SolidPeso molecolare:4073.82Cholecystokinin-J
CAS:Cholecystokinin-J can be used in cholecystography, radiomanometry and biliary cinematography.Formula:C49H66N6O16SColore e forma:SolidPeso molecolare:1027.142,4,6-Tri-tert-butylphenol
CAS:2,4,6-Tri-tert-butylphenol inhibits the Ca2+ ATPase activity of human red blood cell membranes and can be used in related research in the field of life sciences.Formula:C18H30OPurezza:99.55%Colore e forma:SolidPeso molecolare:262.44Amlodipine aspartic acid impurity
CAS:Amlodipine aspartic acid: a calcium blocker with antihypertensive effects; contains specific impurities.Formula:C24H29ClN2O9Purezza:98%Colore e forma:SolidPeso molecolare:524.95Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormula:C36H67N11O8S2Purezza:98%Colore e forma:SolidPeso molecolare:846.12ω-Conotoxin GVIA
CAS:Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.Formula:C120H182N38O43S6Purezza:98%Colore e forma:SolidPeso molecolare:3037O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
CAS:O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1Formula:C20H20ClNO7Colore e forma:SolidPeso molecolare:421.83Cd1a
Cd1a, a β-toxin from the African spider Ceratogyrus darlingi, modulates calcium ion channels and inhibits human calcium ion channels (Ca v 2.2)(IC 50 2.6 μM) asColore e forma:Odour SolidSNX-482
CAS:Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.Formula:C192H274N52O60S7Purezza:98%Colore e forma:SolidPeso molecolare:4495.01Flunarizine
CAS:Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.Formula:C26H26F2N2Purezza:99.9%Colore e forma:SolidPeso molecolare:404.50Atagabalin HCl
CAS:Atagabalin HCl is a novel voltage-dependent calcium channel (VDCC) α2δ subunit (1 and 2) ligand that affects slow-wave sleep and can be used to treat insomnia.Formula:C10H20ClNO2Purezza:99.91% - ≥98%Colore e forma:SoildPeso molecolare:221.72PD 0299685
CAS:PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.Formula:C10H21NO2Purezza:97.20%Colore e forma:SoildPeso molecolare:187.28Linoleic Acid Amide
CAS:<p>Linoleic Acid Amide (Linoleamide) is derived from linoleic acid and regulates Ca2+ flux by inhibiting the sarco/endoplasmic reticulum Ca2+-ATPase.</p>Formula:C18H33NOPurezza:98%Colore e forma:SolidPeso molecolare:279.46Lyso-Globotriaosylceramide (d18:1)
CAS:Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.Formula:C36H67NO17Colore e forma:SolidPeso molecolare:785.922D-myo-Inositol-1,2-diphosphate (sodium salt)
CAS:Ins(1,2)P2, a less potent InsP isomer than Ins(1,4,5)P3, acts as a secondary messenger in cellular signal transmission.Formula:C6H12Na2O12P2Colore e forma:SolidPeso molecolare:384.08Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Colore e forma:LiquidProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Formula:C171H245N53O47S6Purezza:98%Colore e forma:SolidPeso molecolare:3987.511-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Formula:C5H10ClNO2Purezza:>99.99%Colore e forma:SolidPeso molecolare:151.59Elgodipine
CAS:Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.Formula:C29H33FN2O6Purezza:99.84% - 99.98%Colore e forma:SolidPeso molecolare:524.58Cavα2δ-IN-1
CAS:Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a KiFormula:C18H27N5OColore e forma:SolidPeso molecolare:329.448SB-237376
CAS:SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.Formula:C20H25N3O5Purezza:98.88% - 99.81%Colore e forma:SoildPeso molecolare:387.43BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Formula:C34H28N4O4Purezza:98.34%Colore e forma:SolidPeso molecolare:556.61Calcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Colore e forma:Odour SolidRef: TM-L7200
1mgPrezzo su richiesta30μL*10mM (DMSO)Prezzo su richiesta50μL*10mM (DMSO)Prezzo su richiesta100μL*10mM (DMSO)Prezzo su richiesta250μL*10mM (DMSO)Prezzo su richiestaPACAP-38 (31-38), human, mouse, rat TFA
PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.Formula:C49H84F3N17O13Purezza:98%Colore e forma:SolidPeso molecolare:1176.29Mipsagargin
CAS:Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.Formula:C66H100N6O27Purezza:98%Colore e forma:SolidPeso molecolare:1409.52Ref: TM-T8683
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiestaTriphenylethylene
CAS:Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C20H16Colore e forma:White PowderPeso molecolare:256.34Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Colore e forma:Odour SolidCalcium Channel antagonist 4
CAS:Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).Formula:C23H26N2O4SPurezza:98.53%Colore e forma:SolidPeso molecolare:426.53Ethacrynic acid D5
CAS:Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.Formula:C13H12Cl2O4Purezza:98%Colore e forma:SolidPeso molecolare:308.17Flosatidil
CAS:Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,Formula:C26H34F3N3O3SPurezza:99.87% - 99.99%Colore e forma:SolidPeso molecolare:525.63NAADP sodium
NAADP sodium is a Ca2+ motor second messenger that targets Ca(2+) channels and can be used to study cancer and immune dysfunction.Formula:C21H27N6O18P3Colore e forma:SolidPeso molecolare:744.39Ziconotide
CAS:Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Formula:C102H172N36O32S7Purezza:98%Colore e forma:White PowderPeso molecolare:2639.13ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Formula:C215H337N65O70S10Purezza:98%Colore e forma:SolidPeso molecolare:5273.021,4-Dihydropyridine
1,4-Dihydropyridine acts as an antagonist for calcium channels (calcium channel), specifically blocking the L-type calcium channels. This action reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, consequently decreasing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure.Formula:C12H17NO4Colore e forma:SolidPeso molecolare:239.27(±)5(6)-DiHETE
CAS:Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Formula:C20H32O4Colore e forma:SolidPeso molecolare:336.472Chlorocresol
CAS:Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Formula:C7H7ClOColore e forma:SolidPeso molecolare:142.58ω-Conotoxin MVIIC
CAS:Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.Formula:C106H178N40O32S7Purezza:98%Colore e forma:White Lyophilised SolidPeso molecolare:2749Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS:ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.Formula:C12H10ClNO3Purezza:99.17%Colore e forma:SolidPeso molecolare:251.67Budiodarone tartrate
CAS:Budiodarone tartrate (ATI-2042 tartrate) is an antiarrhythmic agent that inhibits calcium channels, and can be used in atrial fibrillation research.Formula:C31H37I2NO11Purezza:97.44%Colore e forma:SolidPeso molecolare:853.44Ref: TM-T74678
1mg170,00€5mg425,00€10mg688,00€25mg1.306,00€50mg2.039,00€100mg2.872,00€1mL*10mM (DMSO)661,00€Levamlodipine besylate Hemipentahydrate
CAS:Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.Formula:C20H25ClN2O5·C6H6O3SH2OColore e forma:SolidPeso molecolare:1224.18MCU-i11
CAS:MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.Formula:C28H28N4O5SPurezza:98.3%Colore e forma:SolidPeso molecolare:532.61Ref: TM-T9960
1mg160,00€5mg359,00€10mg512,00€25mg847,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)437,00€KT-362 free base
CAS:KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.Formula:C22H28N2O3SPurezza:99.91%Colore e forma:SoildPeso molecolare:400.53MMK 1
CAS:Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Formula:C75H123N19O18SPurezza:98%Colore e forma:SolidPeso molecolare:1610.97Glutarimide
CAS:Compound PDK0025, with CAS No. 1121-89-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0025 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C5H7NO2Peso molecolare:113.11Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Formula:C153H266N38O38S2Colore e forma:SolidPeso molecolare:3310.11Fasudil
CAS:Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formula:C14H17N3O2SPurezza:99.79% - 99.84%Colore e forma:SolidPeso molecolare:291.37Lnd 796
CAS:Lnd 796 is an aminosteroid related to LND 623.Formula:C27H45NO7Colore e forma:SolidPeso molecolare:495.65N-Palmitoyl Glycine
CAS:Acyl amides like AEA modulate pain/inflammation. PalGly, similar to N-acyl ethanolamines, inhibits nociception and induces calcium influx in cells.Formula:C18H35NO3Colore e forma:SolidPeso molecolare:313.48Catharanthine
CAS:Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).Formula:C21H24N2O2Purezza:99.11%Colore e forma:White PowderPeso molecolare:336.43CCT129957
CAS:CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity andFormula:C17H15N3O3Purezza:99.69%Colore e forma:SolidPeso molecolare:309.32Ref: TM-T14903
1mg47,00€5mg87,00€10mg133,00€25mg233,00€50mg349,00€100mg525,00€500mg1.111,00€1mL*10mM (DMSO)97,00€(R)-(+)-Bay-K-8644
CAS:<p>(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.</p>Formula:C16H15F3N2O4Purezza:96.51% - 96.51%Colore e forma:SolidPeso molecolare:356.3TPC2-A1-N
CAS:TPC2-A1-N is a TPC2 small molecule agonist that can be used to detect different functions of TPC2 channels in intact cells.Formula:C17H9Cl2F3N2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:401.17Norverapamil-d7 HCl
CAS:Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-gp inhibitor, also a coronary vasodilator.Formula:C26H37ClN2O4Colore e forma:SolidPeso molecolare:484.08(S)-Lercanidipine D3 hydrochloride
CAS:(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.Formula:C36H42ClN3O6Purezza:98%Colore e forma:SolidPeso molecolare:651.21(R)-Nicardipine
CAS:(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Formula:C26H29N3O6Colore e forma:SolidPeso molecolare:479.53MRS1845
CAS:MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).Formula:C21H22N2O6Purezza:99.69%Colore e forma:SolidPeso molecolare:398.41Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Formula:C29H32ClF3N2O3Purezza:99.85%Colore e forma:SolidPeso molecolare:549.02β-Cyfluthrin
CAS:β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.Formula:C22H18Cl2FNO3Colore e forma:SolidPeso molecolare:434.29YM-244769
CAS:YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)Formula:C26H22FN3O3Purezza:95.62%Colore e forma:SolidPeso molecolare:443.47(R)-Lercanidipine-d3 hydrochloride
CAS:(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.Formula:C36H42ClN3O6Purezza:98%Colore e forma:SolidPeso molecolare:651.21YM-244769 dihydrochloride
CAS:YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.Formula:C26H24Cl2FN3O3Purezza:98%Colore e forma:SolidPeso molecolare:516.39Nicardipine-d3 hydrochloride
CAS:Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.Formula:C26H30ClN3O6Purezza:98%Colore e forma:SolidPeso molecolare:519HSK16149
CAS:HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.Formula:C12H19NO2Colore e forma:SolidPeso molecolare:209.28(S)-Nicardipine
CAS:(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Formula:C26H29N3O6Colore e forma:SolidPeso molecolare:479.53Norverapamil-d7
CAS:Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .Formula:C26H36N2O4Purezza:98%Colore e forma:SolidPeso molecolare:447.62Hexadecylphosphoserine TFA
Hexadecylphosphoserine is a type of phospholipid molecule that incorporates a long-chain alkyl group (hexadecyl) and a phosphatidylserine group, granting it high affinity for cell membranes. This compound exhibits antitumor activity by modulating [Ca++]i and related signaling pathways, making it useful for breast cancer research.Formula:C21H41F3NO8PColore e forma:SolidPeso molecolare:523.52Magnesium sulfate
CAS:Magnesium sulfate: anticonvulsant for eclampsia, tocolytic agent.Formula:MgSO4Purezza:98%Colore e forma:SolidPeso molecolare:120.37Etripamil
CAS:Etripamil is a fast-acting intranasal L-type calcium-channel blocker for Paroxysmal Supraventricular Tachycardia.Formula:C27H36N2O4Purezza:99.47% - 99.83%Colore e forma:SolidPeso molecolare:452.59Ref: TM-T15257
1mg55,00€2mg79,00€5mg116,00€10mg172,00€25mg311,00€50mg472,00€100mg707,00€200mg1.111,00€Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5SPurezza:98.85% - 99.99%Colore e forma:SolidPeso molecolare:556.76HA-1004 HCl
CAS:HA-1004 is an inhibitor of PKA, cGKI, PKC, MYLK, and calcium channel protein.Formula:C12H17Cl2N5O2SColore e forma:SolidPeso molecolare:366.27JNJ-26990990
CAS:"JNJ-26990990: broad-spectrum anticonvulsant, less side effects than topiramate, potential for pain and depression treatment; Phase II in 2007."Formula:C9H10N2O2S2Purezza:97.37%Colore e forma:SolidPeso molecolare:242.32Ref: TM-T27673
1mg131,00€5mg286,00€10mg424,00€25mg702,00€50mg938,00€100mg1.311,00€1mL*10mM (DMSO)261,00€Efonidipine
CAS:Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.Formula:C34H38N3O7PPurezza:98.35% - 99.47%Colore e forma:SolidPeso molecolare:631.66Bepridil hydrochloride
CAS:Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channelsFormula:C24H35ClN2OPurezza:99.45% - 99.68%Colore e forma:SolidPeso molecolare:4032,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purezza:97.11%Colore e forma:PelletslargecrystalsPeso molecolare:222.32DHBP dibromide
CAS:DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.Formula:C24H38Br2N2Purezza:99.73%Colore e forma:Yellow To Yellow-Green Powder Or FlakesPeso molecolare:514.38Propiverine hydrochloride
CAS:Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).Formula:C23H30ClNO3Purezza:99.93%Colore e forma:White Crystalling PowerPeso molecolare:403.94Levamlodipine hydrobromide
CAS:Levamlodipine hydrobromide is a medication used to lower blood pressure and prevent chest pain.Formula:C20H26BrClN2O5Colore e forma:SolidPeso molecolare:489.79GSK1016790A
CAS:GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelialFormula:C28H32Cl2N4O6S2Purezza:97.37% - 99.38%Colore e forma:SolidPeso molecolare:655.61Ref: TM-T6848
1mg37,00€2mg48,00€5mg72,00€10mg113,00€25mg240,00€50mg364,00€100mg540,00€1mL*10mM (DMSO)97,00€(+)-Kavain
CAS:(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Formula:C14H14O3Purezza:97% - ≥95%Colore e forma:White Fine PowderPeso molecolare:230.26(±)-Praeruptorin A
CAS:(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.Formula:C21H22O7Purezza:98.9% - 99.73%Colore e forma:SolidPeso molecolare:386.40NS-638
CAS:NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).Formula:C15H11ClF3N3Purezza:98.44%Colore e forma:SolidPeso molecolare:325.72Suvecaltamide
CAS:Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.Formula:C20H23F3N2O2Purezza:99.29% - 99.70%Colore e forma:SolidPeso molecolare:380.4Azumolene sodium anhydrous
CAS:Azumolene sodium, a muscle relaxant, blocks calcium release from muscles and halts SOCE linked to RyR1 except when induced by thapsigargin.Formula:C13H8BrN4NaO3Colore e forma:SolidPeso molecolare:371.13SR33805
CAS:<p>SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)</p>Formula:C32H40N2O5SPurezza:99.15%Colore e forma:SolidPeso molecolare:564.74Mirogabalin besylate
CAS:Mirogabalin besylate is an oral α2δ ligand for voltage-gated calcium channels, with Kd values of 13.5-47.6 nM across species.Formula:C18H25NO5SColore e forma:SolidPeso molecolare:367.46Efonidipine hydrochloride monoethanolate
CAS:Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.Formula:C36H45ClN3O8PPurezza:>99.99%Colore e forma:SolidPeso molecolare:714.18Praeruptorin E
CAS:Praeruptorin C/E relaxes arteries, reduces heart contractility, acting like calcium blockers. D/E protect mice from acid lung injury by halting PMNs and IL-6.Formula:C24H28O7Purezza:98.04% - 99.95%Colore e forma:SolidPeso molecolare:428.47TGR5 Receptor Agonist
CAS:TGR5 is a potent TGR5(GPCR19) agonist.Formula:C18H14Cl2N2O2Purezza:99.77% - ≥95%Colore e forma:SolidPeso molecolare:361.22Ibutilide Fumarate
CAS:Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.Formula:(C20H36N2O3S)2·C4H4O4Purezza:99.68% - 99.74%Colore e forma:SolidPeso molecolare:885.23Ginsenoside Rd
CAS:Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.Formula:C48H82O18Purezza:99.13% - 99.92%Colore e forma:SolidPeso molecolare:947.15Ref: TM-T2878
1mg37,00€5mg71,00€10mg99,00€25mg170,00€50mg260,00€100mg394,00€200mg570,00€1mL*10mM (DMSO)124,00€HC-056456
CAS:HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.Formula:C12H6N2O4S2Purezza:99.62% - 99.65%Colore e forma:SolidPeso molecolare:306.32Ref: TM-T4604
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg170,00€50mg274,00€100mg454,00€1mL*10mM (DMSO)77,00€
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