Canale del calcio
I canali del calcio sono proteine di membrana che regolano il flusso di ioni calcio dentro e fuori dalle cellule, essenziale per varie funzioni cellulari, tra cui la contrazione muscolare, il rilascio di neurotrasmettitori e l'espressione genica. La disfunzione dell'attività dei canali del calcio è associata a condizioni come ipertensione, aritmie cardiache e disturbi neurologici. Presso CymitQuimica, offriamo un'ampia selezione di modulatori dei canali del calcio per supportare la tua ricerca in salute cardiovascolare, neurobiologia e trasduzione del segnale.
Trovati 493 prodotti di "Canale del calcio"
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Cis-22a
CAS:<p>Cis-22a: selective TRPV6 inhibitor (IC50=0.32μM), halts T47D breast cancer cell growth.</p>Formula:C24H30F3N3O2Purezza:99.07%Colore e forma:SolidPeso molecolare:449.51Reldesemtiv
CAS:<p>Reldesemtiv (CK-2127107) boosts exercise capacity, targeting fast muscle troponin, EC50 3.4 μM.</p>Formula:C19H18F2N6OPurezza:97.27%Colore e forma:SolidPeso molecolare:384.38AY 77
CAS:<p>AY 77: Potent, selective PAR2 agonist, favors Ca2+ (ec50=40nM) & ERK1/2 (ec50=2μM), boosts breast cancer cell migration.</p>Formula:C21H32N4O4Purezza:99.7%Colore e forma:SolidPeso molecolare:404.5EMD57033
CAS:<p>EMD57033 activates cardiac troponin C, enhances Ca2+ sensitivity to boost heart contraction.</p>Formula:C22H23N3O4SPurezza:99.72% - >99.99%Colore e forma:SolidPeso molecolare:425.5Bupivacaine hydrochloride monohydrate
CAS:<p>Bupivacaine hydrochloride monohydrate is an NMDA receptor inhibitor that inhibits SCN5A channels and is commonly used in the study of chronic pain.</p>Formula:C18H31ClN2O2Purezza:99.91%Colore e forma:SolidPeso molecolare:342.9Calcium channel-modulator-1
CAS:<p>Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.</p>Formula:C26H24Cl2N2O7SPurezza:99.95%Colore e forma:SolidPeso molecolare:579.45Fluspirilene
CAS:<p>Fluspirilene is a long-acting antipsychotic for schizophrenia, inhibiting L-type calcium channels (IC50: 0.03 μM).</p>Formula:C29H31F2N3OPurezza:99.59%Colore e forma:SolidPeso molecolare:475.57TTA-P1
CAS:<p>TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.</p>Formula:C19H27Cl2FN2OColore e forma:SolidPeso molecolare:389.33SB-423557
CAS:<p>SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM</p>Formula:C28H36N2O4Purezza:98%Colore e forma:SolidPeso molecolare:464.60CCR4 antagonist 2
CAS:<p>CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg</p>Formula:C26H28Cl2N6OPurezza:98%Colore e forma:SolidPeso molecolare:511.45CAD204520
CAS:<p>CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).</p>Formula:C23H32F3N3O2Colore e forma:SolidPeso molecolare:439.51Sesamodil
CAS:<p>Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.</p>Formula:C29H32N2O6SPurezza:98.58% - 99.01%Colore e forma:SolidPeso molecolare:536.64T-Type calcium channel inhibitor 2
<p>Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).</p>Formula:C36H39FN4OSColore e forma:SolidPeso molecolare:594.78Mibefradil dihydrochloride hydrate
CAS:<p>Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.</p>Formula:C29H42Cl2FN3O4Colore e forma:SolidPeso molecolare:586.57Cav 3.2 inhibitor 1
<p>Cav 3.2 inhibitor 1 targets T-type calcium channels, weakly binds D2 receptors, and aids physical and visceral pain research.</p>Formula:C32H39N3OColore e forma:SolidPeso molecolare:481.67SR 33805 oxalate
CAS:<p>Ca2+ channel antagonist</p>Formula:C34H42N2O9SPurezza:98%Colore e forma:SolidPeso molecolare:654.77PD-217014
CAS:<p>PD-217014 is an α2δ ligand that exhibits visceral analgesic activity and can suppress visceral hypersensitivity. Its antihyperalgesic effects are dose-dependent.</p>Formula:C10H17NO2Colore e forma:SolidPeso molecolare:183.25MP-010
CAS:<p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>Formula:C14H20N4O2SColore e forma:SolidPeso molecolare:308.399NNC 55-0396
CAS:<p>NNC 55-0396: Selective T-type calcium channel blocker, IC50 6.8 μM, inhibits human ovarian cancer cell growth.</p>Formula:C30H40Cl2FN3O2Purezza:99.00%Colore e forma:SolidPeso molecolare:564.56Cav 3.2 inhibitor 2
<p>Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.</p>Formula:C32H37F2N3OColore e forma:SolidPeso molecolare:517.65
