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Canale del calcio

Canale del calcio

I canali del calcio sono proteine di membrana che regolano il flusso di ioni calcio dentro e fuori dalle cellule, essenziale per varie funzioni cellulari, tra cui la contrazione muscolare, il rilascio di neurotrasmettitori e l'espressione genica. La disfunzione dell'attività dei canali del calcio è associata a condizioni come ipertensione, aritmie cardiache e disturbi neurologici. Presso CymitQuimica, offriamo un'ampia selezione di modulatori dei canali del calcio per supportare la tua ricerca in salute cardiovascolare, neurobiologia e trasduzione del segnale.

Trovati 493 prodotti di "Canale del calcio"

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  • 1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride

    CAS:
    <p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>
    Formula:C5H10ClNO2
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:151.59
  • NAADP tetrasodium salt

    CAS:
    <p>Ca2+ mobilizing agent</p>
    Formula:C21H27N6O18P3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:744.39
  • Ryanodine

    CAS:
    <p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>
    Formula:C25H35NO9
    Purezza:98%
    Colore e forma:White Solid
    Peso molecolare:493.553
  • Ion Channel Targeted Library


    <p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>
    Colore e forma:Odour Solid
  • Calcium Channel Compound Library


    <p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>
    Colore e forma:Odour Solid
  • KT-362 free base

    CAS:
    <p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>
    Formula:C22H28N2O3S
    Purezza:99.76%
    Colore e forma:Soild
    Peso molecolare:400.53
  • Candidalysin

    CAS:
    <p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>
    Formula:C153H266N38O38S2
    Colore e forma:Solid
    Peso molecolare:3310.11
  • Fasudil

    CAS:
    <p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>
    Formula:C14H17N3O2S
    Purezza:99.79% - 99.84%
    Colore e forma:Solid
    Peso molecolare:291.37
  • 17R(18S)-EpETE

    CAS:
    <p>17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.</p>
    Formula:C20H30O3
    Colore e forma:Solid
    Peso molecolare:318.457
  • Lyso-Globotriaosylceramide (d18:1)

    CAS:
    <p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>
    Formula:C36H67NO17
    Colore e forma:Solid
    Peso molecolare:785.922
  • Levamlodipine besylate Hemipentahydrate

    CAS:
    <p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>
    Formula:C20H25ClN2O5·C6H6O3SH2O
    Colore e forma:Solid
    Peso molecolare:1224.18
  • ILS-920

    CAS:
    <p>ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.</p>
    Formula:C57H86N2O14
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1023.3
  • Cyclic ADP-ribose ammonium


    <p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>
    Colore e forma:Liquid
  • PDDHV

    CAS:
    <p>PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.</p>
    Formula:C49H72O11
    Colore e forma:Solid
    Peso molecolare:837.09
  • Chlorocresol

    CAS:
    <p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>
    Formula:C7H7ClO
    Colore e forma:Solid
    Peso molecolare:142.58
  • ω-Conotoxin GVIA

    CAS:
    <p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>
    Formula:C120H182N38O43S6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3037
  • Flosatidil

    CAS:
    <p>Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,</p>
    Formula:C26H34F3N3O3S
    Purezza:98.29% - 99.60%
    Colore e forma:Solid
    Peso molecolare:525.63
  • GTx1-15


    <p>GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3</p>
    Formula:C176H271N53O45S7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:4073.82
  • Mast cell degranulating peptide (28-49)

    CAS:
    <p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>
    Formula:C110H196N40O24S4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2591.25
  • (±)5(6)-DiHETE

    CAS:
    <p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>
    Formula:C20H32O4
    Colore e forma:Solid
    Peso molecolare:336.472