Canale del calcio
I canali del calcio sono proteine di membrana che regolano il flusso di ioni calcio dentro e fuori dalle cellule, essenziale per varie funzioni cellulari, tra cui la contrazione muscolare, il rilascio di neurotrasmettitori e l'espressione genica. La disfunzione dell'attività dei canali del calcio è associata a condizioni come ipertensione, aritmie cardiache e disturbi neurologici. Presso CymitQuimica, offriamo un'ampia selezione di modulatori dei canali del calcio per supportare la tua ricerca in salute cardiovascolare, neurobiologia e trasduzione del segnale.
Trovati 493 prodotti di "Canale del calcio"
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BX430
CAS:<p>BX430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human P2X4 receptor channels antagonist</p>Formula:C15H15Br2N3OPurezza:97.34%Colore e forma:SolidPeso molecolare:413.11Trimethadione
CAS:<p>Trimethadione (3,5,5,-Trimethyloxazolidine-2,4-dione) is a dione-type anticonvulsant with antiepileptic activity.</p>Formula:C6H9NO3Purezza:99.67% - >99.99%Colore e forma:SolidPeso molecolare:143.145,5-Dimethyloxazolidine-2,4-dione
CAS:<p>5,5-Dimethyloxazolidine-2,4-dione (Dimethadione) is an anticonvulsant that is the active metabolite of TRIMETHADIONE.</p>Formula:C5H7NO3Purezza:99.12%Colore e forma:Drypowder PelletslargecrystalsPeso molecolare:129.11GSK-7975A
CAS:<p>GSK-7975A is a potent and orally available inhibitor of CRAC channel.</p>Formula:C18H12F5N3O2Purezza:98.92%Colore e forma:SolidPeso molecolare:397.3Bupivacaine hydrochloride
CAS:<p>Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.</p>Formula:C18H28N2O·HClPurezza:99.9% - >99.99%Colore e forma:SolidPeso molecolare:324.89Praziquantel
CAS:<p>Praziquantel (Droncit) is an anthelmintic that paralyzes worms by increasing calcium in muscle cells, causing tegument damage and immune response.</p>Formula:C19H24N2O2Purezza:99.67% - 99.69%Colore e forma:SolidPeso molecolare:312.41Nimodipine
CAS:<p>Nimodipine (BAY-e 9736), a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.</p>Formula:C21H26N2O7Purezza:99.64% - 99.79%Colore e forma:SolidPeso molecolare:418.44Ca2+ channel agonist 1
CAS:<p>Ca2+ channel agonist 1 activates N-type Ca2+ channels and inhibits Cdk2 (EC50: 14.23 μM/3.34 μM) for motor nerve issues.</p>Formula:C19H26N6OPurezza:97.71%Colore e forma:SolidPeso molecolare:354.45Strontium ranelate
CAS:<p>Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.</p>Formula:C12H6N2O8S·2SrPurezza:98.97%Colore e forma:Crystalline SolidPeso molecolare:513.49GV-58
CAS:<p>GV-58 agonizes N/P-Q-type Ca2+ channels (EC50: 7.21/8.81 μM) with 20x less inhibition on CDK kinases.</p>Formula:C18H26N6OSPurezza:97.36%Colore e forma:SolidPeso molecolare:374.5Penfluridol
CAS:<p>Penfluridol (TLP-607) is a highly potent antipsychotic.</p>Formula:C28H27ClF5NOPurezza:98.9% - 99.87%Colore e forma:Off-White To White Crystalline PowderPeso molecolare:523.97Felodipine
CAS:<p>Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.</p>Formula:C18H19Cl2NO4Purezza:99.91%Colore e forma:SolidPeso molecolare:384.25Brompheniramine maleate
CAS:<p>Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.</p>Formula:C16H19BrN2·C4H4O4Purezza:99.80%Colore e forma:Crystal PowderPeso molecolare:435.31PACAP-38 (31-38), human, mouse, rat
CAS:<p>PACAP-38 (31-38), human, mouse, rat demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production</p>Formula:C47H83N17O11Purezza:98%Colore e forma:SolidPeso molecolare:1062.27D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Formula:C6H12Na2O12P2Colore e forma:SolidPeso molecolare:384.08PACAP-38 (31-38), human, mouse, rat TFA
<p>PACAP-38 (31-38), human, mouse, rat (TFA) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal.</p>Formula:C49H84F3N17O13Purezza:98%Colore e forma:SolidPeso molecolare:1176.29Nesiritide
CAS:<p>Nesiritide, recombinant human B-type natriuretic peptide, binds NPR-A/C with Kd 7.3/13 pM.</p>Formula:C143H244N50O42S4Purezza:98%Colore e forma:SolidPeso molecolare:3464.04NAADP tetrasodium salt
CAS:<p>Ca2+ mobilizing agent</p>Formula:C21H27N6O18P3Purezza:98%Colore e forma:SolidPeso molecolare:744.39NSC156529
CAS:<p>NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.</p>Formula:C28H21ClS2Purezza:98%Colore e forma:SolidPeso molecolare:457.05D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:<p>Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.</p>Formula:C6H8Na8O18P4Colore e forma:SolidPeso molecolare:675.93Triphenylethylene
CAS:<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formula:C20H16Colore e forma:White PowderPeso molecolare:256.34G-Glu-Ser
CAS:<p>G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.</p>Formula:C8H14N2O6Colore e forma:SolidPeso molecolare:234.21Ryanodine
CAS:<p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>Formula:C25H35NO9Purezza:98%Colore e forma:White SolidPeso molecolare:493.553BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Formula:C34H28N4O4Purezza:98.34%Colore e forma:SolidPeso molecolare:556.61ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Formula:C106H178N40O32S7Purezza:98%Colore e forma:White Lyophilised SolidPeso molecolare:2749Ziconotide
CAS:<p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>Formula:C102H172N36O32S7Purezza:98%Colore e forma:White PowderPeso molecolare:2639.13UK-59811 hydrochloride
CAS:<p>UK-59811 hydrochloride, Br-dihydropyridine derivative, blocks Ca V Ab channels in bacteria, IC50: 194 nM.</p>Formula:C22H30BrClN2O5Colore e forma:SolidPeso molecolare:517.85Calcium Channel antagonist 3
CAS:<p>Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Formula:C23H26N2O4SPurezza:>99.99%Colore e forma:SolidPeso molecolare:426.53Cavα2δ-IN-1
CAS:<p>Cavα2δ-IN-1 demonstrates exceptional specificity for voltage-gated calcium channels Cavα2δ-1 (with a Ki value of 6 nM), in comparison to Cavα2δ-2 (with a Ki</p>Formula:C18H27N5OColore e forma:SolidPeso molecolare:329.448ω-Conotoxin MVIIC TFA
<p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>Formula:C106H178N40O32S7·C2HF3O2Colore e forma:SolidPeso molecolare:2863.27Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Formula:C29H33FN2O6Purezza:98.95% - 99.50%Colore e forma:SolidPeso molecolare:524.58Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Formula:C110H196N40O24S4Purezza:98%Colore e forma:SolidPeso molecolare:2591.25Calcium Channel antagonist 2
CAS:<p>Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.</p>Formula:C23H25FN2O4SPurezza:99.34%Colore e forma:SolidPeso molecolare:444.52Calcium Channel antagonist 4
CAS:<p>Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Formula:C23H26N2O4SPurezza:98.09%Colore e forma:SolidPeso molecolare:426.53Chlorocresol
CAS:<p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>Formula:C7H7ClOColore e forma:SolidPeso molecolare:142.58Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Formula:C153H266N38O38S2Colore e forma:SolidPeso molecolare:3310.112-Nitrobenzoic acid
CAS:<p>2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.</p>Formula:C7H5NO4Purezza:99.97%Colore e forma:SoildPeso molecolare:167.12ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Formula:C120H182N38O43S6Purezza:98%Colore e forma:SolidPeso molecolare:3037Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formula:C20H25ClN2O5·C6H6O3SH2OColore e forma:SolidPeso molecolare:1224.18(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Formula:C20H32O4Colore e forma:SolidPeso molecolare:336.472MMK 1
CAS:<p>Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.</p>Formula:C75H123N19O18SPurezza:98%Colore e forma:SolidPeso molecolare:1610.97Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Colore e forma:LiquidKurtoxin
<p>Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)</p>Formula:C324H478N94O90S8Purezza:98%Colore e forma:SolidPeso molecolare:7386.36SG-094
CAS:<p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>Formula:C30H29NO3Purezza:97.06%Colore e forma:SoildPeso molecolare:451.56Sulcardine 2HCl
CAS:<p>Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.</p>Formula:C24H35Cl2N3O4SPurezza:99.33% - 99.76%Colore e forma:SoildPeso molecolare:532.523Ethacrynic acid D5
CAS:<p>Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.</p>Formula:C13H12Cl2O4Purezza:98%Colore e forma:SolidPeso molecolare:308.17(R)-IDHP
CAS:<p>(R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.</p>Formula:C12H16O5Colore e forma:SolidPeso molecolare:240.25Fasudil
CAS:<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Formula:C14H17N3O2SPurezza:99.79% - 99.84%Colore e forma:SolidPeso molecolare:291.37KT-362 free base
CAS:<p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>Formula:C22H28N2O3SPurezza:99.76%Colore e forma:SoildPeso molecolare:400.53Ser-Ala-alloresact acetate
<p>Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.</p>Formula:C44H75N13O16S2Purezza:99.73%Colore e forma:SolidPeso molecolare:1106.28
