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Canale del calcio

Canale del calcio

I canali del calcio sono proteine di membrana che regolano il flusso di ioni calcio dentro e fuori dalle cellule, essenziale per varie funzioni cellulari, tra cui la contrazione muscolare, il rilascio di neurotrasmettitori e l'espressione genica. La disfunzione dell'attività dei canali del calcio è associata a condizioni come ipertensione, aritmie cardiache e disturbi neurologici. Presso CymitQuimica, offriamo un'ampia selezione di modulatori dei canali del calcio per supportare la tua ricerca in salute cardiovascolare, neurobiologia e trasduzione del segnale.

Trovati 541 prodotti di "Canale del calcio"

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  • Amlodipine aspartic acid impurity

    CAS:
    Amlodipine aspartic acid: a calcium blocker with antihypertensive effects; contains specific impurities.
    Formula:C24H29ClN2O9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:524.95
  • O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine

    CAS:
    O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1
    Formula:C20H20ClNO7
    Colore e forma:Solid
    Peso molecolare:421.83
  • Cd1a


    Cd1a, a β-toxin from the African spider Ceratogyrus darlingi, modulates calcium ion channels and inhibits human calcium ion channels (Ca v 2.2)(IC 50 2.6 μM) as
    Colore e forma:Odour Solid
  • Chlorocresol

    CAS:
    Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.
    Formula:C7H7ClO
    Colore e forma:Solid
    Peso molecolare:142.58
  • Candidalysin

    CAS:
    <p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>
    Formula:C153H266N38O38S2
    Colore e forma:Solid
    Peso molecolare:3310.11
  • Ins(1,4,5)-P3 hexapotassium salt

    CAS:
    <p>D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions.</p>
    Formula:C6H9K6O15P3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:648.64
  • ω-Conotoxin GVIA

    CAS:
    Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.
    Formula:C120H182N38O43S6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:3037
  • Levamlodipine besylate Hemipentahydrate

    CAS:
    <p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>
    Formula:C20H25ClN2O5·C6H6O3SH2O
    Colore e forma:Solid
    Peso molecolare:1224.18
  • (±)5(6)-DiHETE

    CAS:
    Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.
    Formula:C20H32O4
    Colore e forma:Solid
    Peso molecolare:336.472
  • MMK 1

    CAS:
    Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.
    Formula:C75H123N19O18S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:1610.97
  • Cyclic ADP-ribose ammonium


    cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.
    Colore e forma:Liquid
  • 2-Nitrobenzoic acid

    CAS:
    2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.
    Formula:C7H5NO4
    Purezza:99.97%
    Colore e forma:Soild
    Peso molecolare:167.12
  • Kurtoxin


    Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor, exhibiting a dissociation constant (Kd) of 15 nM for the Cav3.1 (α1G T-type)
    Formula:C324H478N94O90S8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:7386.36
  • SG-094

    CAS:
    <p>SG-094 inhibits TPC2, halts RIL175 cell growth, IC50: 3.7 μM for cancer research.</p>
    Formula:C30H29NO3
    Purezza:97.06%
    Colore e forma:Soild
    Peso molecolare:451.56
  • Sulcardine 2HCl

    CAS:
    Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.
    Formula:C24H35Cl2N3O4S
    Purezza:99.33% - 99.76%
    Colore e forma:Soild
    Peso molecolare:532.523
  • ω-Conotoxin MVIIC TFA


    <p>ω-Conotoxin MVIIC TFA is a peptide and neurotoxin blocks P-type and q-type voltage-sensitive neuronal Ca ++ channels (VGCCs) radiolabel immunoprecipitation.</p>
    Formula:C106H178N40O32S7·C2HF3O2
    Colore e forma:Solid
    Peso molecolare:2863.27
  • Ethacrynic acid D5

    CAS:
    Ethacrynic acid: a diuretic, anti-inflammatory, inhibits calcium channels, GSTs, NF-kB pathway, and modulates leukotriene; has deuterium-labeled form.
    Formula:C13H12Cl2O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:308.17
  • (R)-IDHP

    CAS:
    (R)-IDHP, a salvia derivative, relaxes blood vessels by blocking calcium channels, aiding cardiovascular research.
    Formula:C12H16O5
    Colore e forma:Solid
    Peso molecolare:240.25
  • MCU-i11

    CAS:
    MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
    Formula:C28H28N4O5S
    Purezza:98.3%
    Colore e forma:Solid
    Peso molecolare:532.61
  • Ser-Ala-alloresact acetate


    <p>Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.</p>
    Formula:C44H75N13O16S2
    Purezza:99.73%
    Colore e forma:Solid
    Peso molecolare:1106.28