PDE
Le fosfodiesterasi (PDEs) sono enzimi che idrolizzano i nucleotidi ciclici, come cAMP e cGMP, nelle loro forme inattive, svolgendo un ruolo chiave nella regolazione delle vie di segnalazione intracellulare. Gli inibitori delle PDE sono utilizzati nel trattamento di varie condizioni, tra cui malattie cardiovascolari, disfunzione erettile e disturbi respiratori, grazie alla loro capacità di modulare i livelli di nucleotidi ciclici. Presso CymitQuimica, offriamo una gamma di inibitori delle PDE per supportare la tua ricerca nella segnalazione cellulare, farmacologia e sviluppo terapeutico.
Trovati 166 prodotti di "PDE"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
AN3199
CAS:AN3199 is a selective inhibitor of PDE4 with an IC50 of 94.5 nM.Formula:C17H18BNO5Purezza:99.45%Colore e forma:SolidPeso molecolare:327.14K134
CAS:K134 is an inhibitor of phosphodiesterase 3. The IC50s of K134 for PDE3A, PDE3B, PDE5, PDE2 and PDE4 are 0.1, 0.28, 12.1, >300 and >300 μM, respectively.Formula:C22H29N3O4Purezza:98%Colore e forma:SolidPeso molecolare:399.48AWD 12-281
CAS:<p>AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).</p>Formula:C22H14Cl2FN3O3Purezza:99.25% - 99.85%Colore e forma:SolidPeso molecolare:458.27Carbazeran
CAS:<p>Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases.</p>Formula:C18H24N4O4Purezza:99.3%Colore e forma:SolidPeso molecolare:360.41Tofimilast
CAS:Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.Formula:C18H21N5SPurezza:99.55%Colore e forma:SolidPeso molecolare:339.46Mopidamol
CAS:Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimentalFormula:C19H31N7O4Purezza:99.31% - 99.78%Colore e forma:SolidPeso molecolare:421.49Dasantafil
CAS:Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Formula:C22H28BrN5O5Purezza:99.4% - 99.50%Colore e forma:SolidPeso molecolare:522.39Dovramilast
CAS:Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.Formula:C24H28N2O6SPurezza:98.75% - 99.62%Colore e forma:SolidPeso molecolare:472.55Verofylline
CAS:Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for theFormula:C12H18N4O2Purezza:98.4% - 99.8%Colore e forma:SolidPeso molecolare:250.3Isomazole
CAS:<p>Isomazole is a novel orally available phosphodiesterase (PDE) inhibitor with calcium-sensitizing properties that inhibits PDE3 and PDE4.</p>Formula:C14H13N3O2SPurezza:98.66%Colore e forma:SolidPeso molecolare:287.34PDE IV-IN-1
CAS:PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary diseaseFormula:C20H23ClN4O2Purezza:99.79%Colore e forma:SolidPeso molecolare:386.88PDE4B-IN-2
CAS:PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.Formula:C19H18ClN3O2SPurezza:99.32%Colore e forma:SolidPeso molecolare:387.88uk-50001
CAS:UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.Formula:C26H24F3N3O4Purezza:99.90%Colore e forma:SolidPeso molecolare:499.48Autotaxin-IN-3
CAS:Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.Formula:C22H21N9O2Purezza:99.54% - 99.79%Colore e forma:SolidPeso molecolare:443.46PF-04447943
CAS:PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.Formula:C20H25N7O2Purezza:99.36% - 99.59%Colore e forma:SolidPeso molecolare:395.46Filaminast
CAS:Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.Formula:C15H20N2O4Purezza:98.93% - 99.99%Colore e forma:SolidPeso molecolare:292.33MK-0873
CAS:MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.Formula:C25H18N4O3Purezza:99.14%Colore e forma:SolidPeso molecolare:422.44Nanterinone
CAS:Nanterinone: oral phosphodiesterase inhibitor, improves acute heart failure hemodynamics.Formula:C15H15N3OPurezza:99.96%Colore e forma:SolidPeso molecolare:253.3PF-04957325
CAS:PF-04957325 is an inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A.PF-04957325 can be used for the study of autoimmune encephalomyelitis.Formula:C14H15F3N8OSPurezza:99.02%Colore e forma:SolidPeso molecolare:400.38PDE5-IN-2
CAS:PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)Formula:C25H21N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:491.52
