Glucokinasi
La glucocinasi (GK) è un enzima che catalizza la fosforilazione del glucosio a glucosio-6-fosfato, un passaggio critico nella glicolisi. La GK è espressa principalmente nel fegato e nel pancreas, dove svolge un ruolo chiave nella regolazione dei livelli di glucosio nel sangue. Gli inibitori della GK sono di interesse nello studio dei disturbi metabolici come il diabete, poiché possono modulare il metabolismo del glucosio e la secrezione di insulina. Presso CymitQuimica, offriamo inibitori della glucocinasi per supportare la tua ricerca sul diabete, il metabolismo e lo sviluppo terapeutico.
Trovati 57 prodotti di "Glucokinasi"
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RO-28-1675
CAS:RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.Formula:C18H22N2O3S2Purezza:98.13%Colore e forma:SolidPeso molecolare:378.51Ref: TM-T16793
1mg58,00€5mg123,00€10mg187,00€25mg376,00€50mg617,00€100mg938,00€200mg1.311,00€1mL*10mM (DMSO)135,00€GKA-22
CAS:GKA-22 is a human glucokinase allosteric activator in the absence of glucose.Formula:C22H22N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:426.49AMG-1694
CAS:AMG-1694 disrupts GK-GKRP complex, enhancing GK activity with 7 nM IC50; normalizes glucose in diabetic rodents without affecting normoglycemic animals.Formula:C23H30F3N3O4S2Purezza:98.37%Colore e forma:SolidPeso molecolare:533.63CM-10-18
CAS:CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.Formula:C17H35NO5Colore e forma:SolidPeso molecolare:333.46AZD-1656
CAS:AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2Formula:C24H26N6O5Purezza:97.07% - 99.37%Colore e forma:SolidPeso molecolare:478.5AZD1092
CAS:AZD1092 is the glucokinase enzyme activator.Formula:C24H26N4O5Purezza:98%Colore e forma:SolidPeso molecolare:450.49AR453588
CAS:AR453588 is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.Formula:C25H25N7O2S2Colore e forma:SolidPeso molecolare:519.64PF-04937319
CAS:<p>PF-04937319 activates glucokinase (EC50=154.4μM) with low hypoglycemia risk, researched for type 2 diabetes treatment.</p>Formula:C22H20N6O4Purezza:99.89%Colore e forma:SolidPeso molecolare:432.43KDM4-IN-2
CAS:KDM4-IN-2 is a potent and selective KDM4/KDM5 dual inhibitor with Kis of 4 and 7 nM for KDM4A and KDM5B, respectively.Formula:C25H26N6OPurezza:98%Colore e forma:SolidPeso molecolare:426.51AR453588 hydrochloride
CAS:AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.Formula:C25H26ClN7O2S2Purezza:98%Colore e forma:SolidPeso molecolare:556.1WAY-297848
CAS:WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.Formula:C13H13ClN2O2SPurezza:98.19%Colore e forma:SolidPeso molecolare:296.77Glucokinase activator 7
CAS:Glucokinase activator7 is an activator of glucose kinase (Glucokinase) and can be utilized in research on diabetes and hyperglycemia [refer to compound on page 176].Formula:C14H13N3O2SColore e forma:SolidPeso molecolare:287.337GKA50 quarterhydrate
GKA50 quarterhydrate: glucokinase activator, EC50 of 33 nM, boosts insulin, cuts glucose in rats.Formula:C26H30N2O7Colore e forma:SolidPeso molecolare:469.01Gcase activator 2
CAS:Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.Formula:C21H24N4O2Purezza:99.51% - 99.76%Colore e forma:SolidPeso molecolare:364.44Glucokinase activator 8
CAS:Glucokinase activator8 is an activator of glucose kinase (glucokinase).Formula:C14H13N3O2SColore e forma:SolidPeso molecolare:287.337MK-0941
CAS:MK-0941 is an orally active and allosteric glucokinase activator, has potential in the treatment of type 2 diabetes.Formula:C22H28N4O9S2Colore e forma:SolidPeso molecolare:556.61GKA50
CAS:GKA50 stimulates insulin release from mouse islets of Langerhans and MIN6 cells. GKA50 shows significant glucose lowering in high fat fed female rats. GKA50 is a potent glucokinase activator (EC50=33 nM at 5 mM glucose).Formula:C26H28N2O6Purezza:98%Colore e forma:SolidPeso molecolare:464.51
