Caseina chinasi
Le caseina chinasi sono una famiglia di proteine chinasi serina/treonina che regolano vari processi cellulari, tra cui la riparazione del DNA, i ritmi circadiani e la trasduzione del segnale. Queste chinasi sono coinvolte nella fosforilazione di numerose proteine e sono implicate in malattie come il cancro, i disturbi neurodegenerativi e le sindromi metaboliche. Presso CymitQuimica, offriamo una selezione di inibitori della caseina chinasi per supportare la tua ricerca nella trasduzione del segnale, nella regolazione del ciclo cellulare e nello sviluppo terapeutico.
Trovati 138 prodotti di "Caseina chinasi"
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LY-364947
CAS:LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.Formula:C17H12N4Purezza:99.65% - 99.96%Colore e forma:SolidPeso molecolare:272.3Ref: TM-T2048
5mg62,00€10mg78,00€25mg136,00€50mg241,00€100mg354,00€200mg530,00€500mg830,00€1mL*10mM (DMSO)69,00€Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Formula:C31H24F3N5O3Purezza:99.56% - 99.56%Colore e forma:White SolidPeso molecolare:571.55Ref: TM-T4976
1mg48,00€2mg65,00€5mg96,00€10mg170,00€25mg343,00€50mg449,00€100mg658,00€1mL*10mM (DMSO)120,00€TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Formula:C6HBr4N3Purezza:98.51% - 99.45%Colore e forma:Off-White SolidPeso molecolare:434.71CKI-7
CAS:CKI-7 is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H14Cl3N3O2SPurezza:>99.99%Colore e forma:SolidPeso molecolare:358.67Ref: TM-T19913
1mg108,00€5mg207,00€10mg309,00€25mg497,00€50mg675,00€100mg909,00€200mg1.224,00€1mL*10mM (DMSO)225,00€Umbralisib hydrochloride
CAS:Umbralisib hydrochloride: PI3Kδ inhibitor; IC50=22.2 nM, EC50=24.3 nM; active vs CK1ε, EC50=6.0 μM.Formula:C31H25ClF3N5O3Purezza:98%Colore e forma:SolidPeso molecolare:608.01NCC007
CAS:NCC007 is a novel CKIα and CKIδ dual inhibitors by structural modification of N9 and C2 position of longdaysin.Formula:C22H28F3N7Purezza:98.88%Colore e forma:SolidPeso molecolare:447.5CK1-IN-1
CAS:CK1-IN-1, a CK1 inhibitor with IC50: 15nM CK1δ, 16nM CK1ε, 73nM p38σ; patent WO2015119579A1.Formula:C24H15F2N3Purezza:98.79%Colore e forma:SolidPeso molecolare:383.39Ref: TM-T5393
1mg47,00€2mg62,00€5mg92,00€10mg152,00€25mg289,00€50mg447,00€100mg670,00€1mL*10mM (DMSO)101,00€DMAT
CAS:DMAT (Casein kinase II Inhibitor) is a potent and specific inhibitor of CK2(IC50 value of 130 nM).Formula:C9H7Br4N3Purezza:99.48%Colore e forma:SolidPeso molecolare:476.79TAK-715
CAS:TAK-715 is a p38 MAPK inhibitor for p38α.Formula:C24H21N3OSPurezza:99.83%Colore e forma:SolidPeso molecolare:399.51Ref: TM-T6150
1mg38,00€2mg50,00€5mg82,00€10mg94,00€25mg166,00€50mg306,00€100mg480,00€1mL*10mM (DMSO)92,00€Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Formula:C12H10ClN7Purezza:99.45%Colore e forma:SolidPeso molecolare:287.71Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purezza:99.97%Colore e forma:SolidPeso molecolare:335.33PF-670462
CAS:PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.Formula:C19H22Cl2FN5Purezza:99.42% - 99.72%Colore e forma:SolidPeso molecolare:410.32XL413
CAS:XL-413 is an oral CDC7 kinase inhibitor, potentially blocking DNA replication, mitosis, and cancer cell growth.Formula:C14H12ClN3O2Purezza:98.40% - 99.94%Colore e forma:SolidPeso molecolare:289.72SSTC3
CAS:SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.Formula:C23H17F3N4O3S2Purezza:98.65% - 99.94%Colore e forma:SolidPeso molecolare:518.53Ref: TM-T13004
1mg99,00€5mg235,00€10mg376,00€25mg615,00€50mg867,00€100mg1.159,00€1mL*10mM (DMSO)238,00€AMG-548
CAS:AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.Formula:C29H27N5OPurezza:99.91%Colore e forma:SolidPeso molecolare:461.56SR-1277
CAS:SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.Formula:C21H19N9O3SColore e forma:SolidPeso molecolare:477.5CK2/PIM1-IN-1
CAS:CK2/PIM1-IN-1 inhibits CK2 & PIM1 (IC50s: 3.787 & 4.327 μM), aimed for cancer research.Formula:C15H9NO4S2Purezza:98%Colore e forma:SolidPeso molecolare:331.374,5,6,7-Tetrabromobenzimidazole
CAS:4,5,6,7-Tetrabromobenzimidazole is a selective and ATP-competitive inhibitor of protein kinase CK2 [1].Formula:C7H2Br4N2Colore e forma:SolidPeso molecolare:433.72CK2-IN-9
CAS:CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporterFormula:C23H29N9OColore e forma:SolidPeso molecolare:447.54Quinalizarin
CAS:Quinalizarin, the most selective CK2 inhibitor, is superior to CX-4945 which is the first-in-class CK2 inhibitor.Formula:C14H8O6Purezza:98%Colore e forma:SolidPeso molecolare:272.21Tyrphostin AG 1112
CAS:Tyrphostin AG 1112 is a Bcr-Abl kinase blocker. It can activate the terminal differentiation of K562 cells and the purging of Ph+ cells.Formula:C15H10N6Colore e forma:SolidPeso molecolare:274.28PF 4800567 hydrochloride
CAS:casein kinase 1ε inhibitorFormula:C17H19Cl2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:396.27IQA
CAS:IQA is a casein kinase 2 (CK2) inhibitor.Formula:C17H12N2O3Colore e forma:SolidPeso molecolare:292.29(R)-DRF053 dihydrochloride
CAS:cdk/CK1 inhibitor,potent and ATP-competitiveFormula:C23H29Cl2N7OPurezza:98%Colore e forma:SolidPeso molecolare:490.43TMCB
CAS:CK2 and ERK8 inhibitorFormula:C11H9Br4N3O2Purezza:98%Colore e forma:SolidPeso molecolare:534.82CK2-IN-6
CAS:CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.Formula:C19H16ClN7O2Colore e forma:SolidPeso molecolare:409.83SRPIN-803
CAS:SRPIN-803 is a selective dual SRPK1 and CK2 inhibitor.Formula:C14H9F3N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:370.31Umbralisib sulfate
CAS:Umbralisib sulfate, an oral dual PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), targets CLL T cells for blood cancer research.Formula:C31H26F3N5O7SColore e forma:SolidPeso molecolare:669.63Umbralisib tosylate
CAS:Umbralisib tosylate, an oral PI3Kδ/CK1ε inhibitor (EC50: 22.2 nM/6.0 μM), shows promise for CLL research.Formula:C38H32F3N5O6SColore e forma:SolidPeso molecolare:743.75BTX161
CAS:BTX161: potent CKIα degrader, surpasses Lenalidomide in AML, triggers DDR + p53, stabilizes MDM2.Formula:C15H16N2O3Colore e forma:SolidPeso molecolare:272.3HDAC/CK2-IN-1
CAS:HDAC/CK2-IN-1 (compound 38) acts as an inhibitor of HDAC1 (IC 50 = 1.46 μM), HDAC6 (IC 50 = 0.66 μM), and CK2 (IC 50 = 3.67 μM). It demonstrates promising antiproliferative effects on various cell lines, including Jurkat, MCF-7, HCT-116, and HL-60.Formula:C15H18Br4N4O2Colore e forma:SolidPeso molecolare:605.95CK2-IN-4
CAS:CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.Formula:C18H11N3O4SPurezza:99.65%Colore e forma:SolidPeso molecolare:365.36CK2α-IN-1
CAS:CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and canFormula:C16H11N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:341.34CK1-IN-2
CAS:CK1-IN-2 (compound Nr.4) is a potent CK1 inhibitor p38a, and is used in DUX4 overexpression-associated diseases, such as muscular dystrophy.Formula:C17H12FN3O2Purezza:99.31%Colore e forma:SolidPeso molecolare:309.29XL413 xHCl
CAS:BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215
Formula:C14H12ClN3O2·xHClPurezza:99.37% - 99.67%Colore e forma:SolidPeso molecolare:326.18HS-276
CAS:HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formula:C24H29N5O2Purezza:97.67% - 98.81%Colore e forma:SolidPeso molecolare:419.52Ref: TM-T62209
1mg66,00€5mg144,00€10mg219,00€25mg430,00€50mg690,00€100mg1.064,00€200mg1.434,00€1mL*10mM (DMSO)170,00€PI-828
CAS:PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.Formula:C19H18N2O3Purezza:99.95%Colore e forma:SolidPeso molecolare:322.36Ref: TM-T16528
1mg35,00€5mg78,00€10mg117,00€25mg197,00€50mg283,00€100mg386,00€200mg550,00€1mL*10mM (DMSO)55,00€BioE-1115
CAS:BioE-1115 is a selective and potent inhibitor of serine-threonine protein kinase (PASK, IC50 = 4 nM). BioE-1115 is a potent inhibitor of CK2α (IC50 = 10 μM).Formula:C19H18FN3O2Purezza:97.54%Colore e forma:SolidPeso molecolare:339.36Ref: TM-T10547
5mg34,00€10mg44,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)34,00€Casein kinase 1δ-IN-1
CAS:Casein kinase 1δ-IN-1 (WAY-643895) is an inhibitor of casein kinase 1δ (CK1δ), which inhibits CK1δ.Formula:C11H7N3OSPurezza:99.89%Colore e forma:SolidPeso molecolare:229.26Casein kinase 1δ-IN-4
CAS:"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."Formula:C16H12N6SPurezza:98%Colore e forma:SolidPeso molecolare:320.37PF-05236216
CAS:PF-05236216 is a potent, selective, brain-penetrant CK1δ/ε inhibitor that modulates circadian rhythms in mice, supporting sleep and metabolic research.Formula:C18H15FN4OPurezza:100% - 100%Colore e forma:SolidPeso molecolare:322.34ON 108600
CAS:ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.Formula:C22H14Cl2N2O6S2Purezza:98%Colore e forma:SolidPeso molecolare:537.39BAY-204
CAS:BAY-204 is a CSNK1α/δ inhibitor that can be used in the treatment of proliferative diseases.Formula:C29H26F3N5O2Colore e forma:SolidPeso molecolare:533.54Casein kinase 1δ-IN-5
CAS:Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects inFormula:C16H11F3N2OSPurezza:99.62%Colore e forma:SolidPeso molecolare:336.33Ref: TM-T79154
2mgPrezzo su richiesta5mg63,00€10mgPrezzo su richiesta25mgPrezzo su richiesta50mg258,00€100mgPrezzo su richiestaTID43
CAS:TID43, a CK2 inhibitor, exhibits potent inhibition with an IC50 value of 0.3 μM. It is applicable in anti-angiogenic research [1].Formula:C10H3I4NO4Colore e forma:SolidPeso molecolare:708.755XL413 hydrochloride
CAS:XL413 hydrochloride (BMS-863233 Hydrochloride) is a potent, selective and ATP competitive inhibitor of Cdc7. XL413 hydrochloride also inhibits CK2 and PIM1.Formula:C14H13Cl2N3O2Purezza:98.81% - 99.8%Colore e forma:SolidPeso molecolare:326.18Ref: TM-T6735
1mg50,00€5mg109,00€10mg152,00€25mg268,00€50mg447,00€100mg672,00€200mg888,00€500mg1.369,00€Ac-VDVAD-CHO
CAS:Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].Formula:C23H37N5O10Purezza:98%Colore e forma:SolidPeso molecolare:543.57Casein Kinase II Inhibitor IV
CAS:Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.Formula:C24H23N5O3Purezza:99.65% - 99.75%Colore e forma:SolidPeso molecolare:429.47Ref: TM-T10687
1mg87,00€5mg170,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€500mg1.624,00€1mL*10mM (DMSO)180,00€Casein kinase 1δ-IN-10
CAS:Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).Formula:C21H17N3O3Purezza:98%Colore e forma:SolidPeso molecolare:359.38
