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Recettore dei retinoidi

Recettore dei retinoidi

I recettori dei retinoidi sono recettori nucleari che mediano gli effetti dei retinoidi (derivati della vitamina A) sull'espressione genica. Questi recettori svolgono un ruolo vitale nella differenziazione cellulare, proliferazione e apoptosi. Gli inibitori dei recettori dei retinoidi sono utilizzati per studiare il loro coinvolgimento in varie malattie, tra cui il cancro, i disturbi della pelle e le condizioni metaboliche. Modulando l'attività dei recettori dei retinoidi, questi inibitori possono fornire informazioni sui meccanismi di segnalazione dei retinoidi e sul loro potenziale terapeutico. Presso CymitQuimica, offriamo inibitori dei recettori dei retinoidi per supportare la tua ricerca in dermatologia, oncologia e regolazione metabolica.

Trovati 20 prodotti per "Recettore dei retinoidi".

  • Logo CymitQuimica
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    RXR agonist 3

    RXR agonist 3 (Compound 35) is a potent partial agonist of RXR, showing EC50 values of 3 nM for RXRα, 3 nM for RXRβ, and 8 nM for RXRγ. It is applicable in research related to Alzheimer's disease, multiple sclerosis, and lymphoma.

    Ref: TM-T214644

  • BMS 195614
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    BMS 195614

    CAS:
    BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.
    Formula:C29H24N2O3
    Purezza:97.14%
    Colore e forma:White Solid
    Peso molecolare:448.51

    Ref: TM-T22192

  • CD3254
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    CD3254

    CAS:
    CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
    Formula:C24H28O3
    Purezza:98.71% - 98.71%
    Colore e forma:Yellow Solid
    Peso molecolare:364.48

    Ref: TM-T14912

  • AR7
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    AR7

    CAS:
    AR7 is a retinoic acid receptor α (RARα) antagonist.
    Formula:C15H12ClNO
    Purezza:98.12% - 99.86%
    Colore e forma:White Solid
    Peso molecolare:257.715

    Ref: TM-T3955

  • BMS270394
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    BMS270394

    CAS:
    BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.
    Formula:C23H26FNO4
    Colore e forma:White Solid
    Peso molecolare:399.46

    Ref: TM-T26846

  • BMS 961
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    BMS 961

    CAS:
    BMS 961 is an RARγ-selective agonist used to profile coregulator binding signatures and to induce TSLP expression in mouse keratinocytes, supporting research on RARγ transcription and epithelial immune signaling.
    Formula:C23H26FNO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:399.46

    Ref: TM-T22611

  • CD2665
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    CD2665

    CAS:
    CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.
    Formula:C31H34O5
    Purezza:99.71%
    Colore e forma:White Solid
    Peso molecolare:486.6

    Ref: TM-T14911

  • MM 11253
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    MM 11253

    CAS:
    MM 11253 is a RARγ antagonist with IC50 of 44nM.
    Formula:C28H30O2S2
    Purezza:99.41%
    Colore e forma:Solid
    Peso molecolare:462.67

    Ref: TM-T23005

  • BMS 753
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    BMS 753

    CAS:
    BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).
    Formula:C21H21NO4
    Purezza:98.55%
    Colore e forma:Solid
    Peso molecolare:351.4

    Ref: TM-T22049

  • AC-261066
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    AC-261066

    CAS:
    AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.
    Formula:C17H20FNO4S
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:353.41

    Ref: TM-T14089

  • Ch55
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    Ch55

    CAS:
    Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.
    Formula:C24H28O3
    Purezza:99.55%
    Colore e forma:Solid
    Peso molecolare:364.48

    Ref: TM-T14946

  • Fluorobexarotene
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    Fluorobexarotene

    CAS:
    Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.
    Formula:C24H27FO2
    Purezza:99.08%
    Colore e forma:Solid
    Peso molecolare:366.4684

    Ref: TM-T11303

  • BMS641
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    BMS641

    CAS:
    BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and RARgamma to induce cell maturation.
    Formula:C27H23ClO2
    Purezza:98.11%
    Colore e forma:Solid
    Peso molecolare:414.92

    Ref: TM-T26854

  • KCL-286
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    KCL-286

    CAS:
    KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).
    Formula:C19H14N2O4
    Purezza:99.88%
    Colore e forma:Solid
    Peso molecolare:334.33

    Ref: TM-T78575

  • ER 50891
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    ER 50891

    CAS:
    ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.
    Formula:C29H24N2O2
    Purezza:99.43%
    Colore e forma:Solid
    Peso molecolare:432.51

    Ref: TM-T22767

  • LE135
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    LE135

    CAS:
    LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).
    Formula:C29H30N2O2
    Purezza:97.94%
    Colore e forma:Solid
    Peso molecolare:438.56

    Ref: TM-T22920

  • ZSH-2208
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    ZSH-2208

    CAS:
    ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.
    Formula:C20H18O3S
    Purezza:99.81%
    Colore e forma:Solid
    Peso molecolare:338.42

    Ref: TM-T205434

  • Logo CymitQuimica
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    BMS-948

    CAS:
    BMS-948 is a selective RARβ transcriptional agonist with an EC50 of 0.1 μM. It is utilized in research pertaining to tumor diseases, embryonic development, and tissue remodeling.
    Formula:C24H17NO3
    Peso molecolare:367.40

    Ref: TM-T218334

  • Logo CymitQuimica
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    LE-540

    CAS:
    LE-540 is a selective retinoic acid receptor β (RARβ) antagonist with a Ki value of 0.22 μM. It shows potential for use in cancer research, particularly in studies focusing on breast and lung cancer.
    Formula:C33H32N2O2
    Peso molecolare:488.63

    Ref: TM-T213143

  • BMS453
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    BMS453

    CAS:
    BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.
    Formula:C27H24O2
    Purezza:99.93%
    Colore e forma:White Solid
    Peso molecolare:380.48

    Ref: TM-T21714