Fattore Xa
Il fattore Xa è un enzima cruciale nella cascata della coagulazione che converte la protrombina in trombina, portando alla formazione di coaguli di sangue. L'inibizione del fattore Xa è una strategia terapeutica ampiamente utilizzata per prevenire e trattare i disturbi tromboembolici, come la trombosi venosa profonda, l'embolia polmonare e l'ictus. Presso CymitQuimica, offriamo inibitori del fattore Xa per supportare la tua ricerca in ematologia, salute cardiovascolare e terapia anticoagulante.
Trovati 85 prodotti di "Fattore Xa"
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Darexaban glucuronide
CAS:Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.Formula:C33H38N4O10Colore e forma:SolidPeso molecolare:650.68Razaxaban hydrochloride
CAS:Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.Formula:C24H21ClF4N8O2Purezza:98%Colore e forma:SolidPeso molecolare:564.92YM-75466
CAS:YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.Formula:C28H35N5O8S2Colore e forma:SolidPeso molecolare:633.74Ciraparantag TFA
CAS:Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.Formula:C26H50F6N12O6Purezza:98%Colore e forma:SolidPeso molecolare:740.74BMS 740808
CAS:BMS-740808 is a highly effective and selective factor X inhibitor.Formula:C31H27F3N6O3Colore e forma:SolidPeso molecolare:588.58Pegnivacogin
CAS:Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.Formula:C20H40N3O11PPurezza:98%Colore e forma:SolidPeso molecolare:529.52Tanogitran
CAS:Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.Formula:C25H31N7O3Purezza:98%Colore e forma:SolidPeso molecolare:477.56DPC-423
CAS:DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.Formula:C25H21ClF4N4O3SPurezza:98%Colore e forma:SolidPeso molecolare:568.97Ciraparantag
CAS:Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.Formula:C22H48N12O2Purezza:98%Colore e forma:SolidPeso molecolare:512.7Milvexian TFA
CAS:Milvexian (BMS-986177/JNJ-70033093) is a factor XIa inhibitor with Ki=44 nM for kallikrein, Ki=35 nM for chymotrypsin, 32% bioavailability.Formula:C30H26Cl2F5N9O4Colore e forma:SolidPeso molecolare:742.49Otamixaban
CAS:Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.Formula:C25H26N4O4Purezza:98.08%Colore e forma:SolidPeso molecolare:446.5Eribaxaban
CAS:Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.Formula:C24H22ClFN4O4Purezza:98.99% - 99.13%Colore e forma:SolidPeso molecolare:484.91Zifaxaban
CAS:Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.Formula:C20H16ClN3O4SPurezza:97.46% - 99.82%Colore e forma:SolidPeso molecolare:429.88Ref: TM-T29215
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€Edoxaban
CAS:Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.Formula:C24H30ClN7O4SPurezza:97.67% - 99.71%Colore e forma:SolidPeso molecolare:548.06Fidexaban
CAS:Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assaysFormula:C25H24F2N6O5Purezza:97.27% - 99.43%Colore e forma:SolidPeso molecolare:526.49LY 517717
CAS:LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).Formula:C27H33N5O2Purezza:99.77% - 99.88%Colore e forma:SolidPeso molecolare:459.58BMS-962212
CAS:BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.Formula:C32H28ClFN8O5Purezza:98%Colore e forma:SolidPeso molecolare:659.07BI-11634
CAS:BI-11634 is a factor Xa inhibitor.Formula:C22H23ClN4NaO4Purezza:98%Colore e forma:SolidPeso molecolare:465.89AS1468240
CAS:AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.Formula:C25H25Cl2N5O3Colore e forma:SolidPeso molecolare:514.4BMS-654457
CAS:BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).Formula:C36H37N5O4Purezza:98%Colore e forma:SolidPeso molecolare:603.71BMS-262084
CAS:BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.Formula:C18H31N7O5Colore e forma:SolidPeso molecolare:425.48FXIa-IN-1
CAS:FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.Formula:C20H19F3N4O5Purezza:98%Colore e forma:SolidPeso molecolare:452.38Frunexian
CAS:Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.Formula:C19H26N4O4Purezza:98%Colore e forma:SolidPeso molecolare:374.43FXIa-IN-7
CAS:FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.Formula:C28H28N2O4Purezza:98.55%Colore e forma:SolidPeso molecolare:456.53FXa-IN-1
CAS:FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.Formula:C24H18F5N5OColore e forma:SolidPeso molecolare:487.42Dechloro Rivaroxaban
CAS:Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.Formula:C19H19N3O5SPurezza:98.63%Colore e forma:SolidPeso molecolare:401.44Ref: TM-T78215
5mg40,00€10mg63,00€25mg107,00€50mg170,00€100mg264,00€200mg418,00€1mL*10mM (DMSO)44,00€RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Formula:C18H24N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:436.49FXIa-IN-10
FXIa-IN-10 is a potent, orally bioavailable inhibitor of Activator XI (FXIa) (Ki: 0.17 nM).Formula:C23H18Cl2F3N9O2Colore e forma:SolidPeso molecolare:580.35FXIa-6f
CAS:FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical speciesFormula:C31H29ClF2N4O4Colore e forma:SolidPeso molecolare:595.04DX-9065A HCl hydrate
CAS:DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.Formula:C26H39ClN4O8Purezza:98%Colore e forma:SolidPeso molecolare:571.06FXIa-IN-9
CAS:FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.Formula:C23H18Cl2F3N9O2Colore e forma:SolidPeso molecolare:580.35BAY 3389934
CAS:BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.Formula:C26H30ClN5O7S2Colore e forma:SolidPeso molecolare:624.129FXIa-IN-6
CAS:FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.Formula:C31H29ClF2N4O4Colore e forma:SolidPeso molecolare:595.04FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Colore e forma:Solid5-Chlorothiophene-2-carboxylic acid
CAS:5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.Formula:C5H3ClO2SColore e forma:SolidPeso molecolare:162.59
