Lipasi

<p>Lipase 65 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 7-8 and temp. optimum at 30-40°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 65 was shown to hydrolyze p-Nitrophenyl esters of butyrate (100 % activity), octanoate (87 %), laurate (5 %), palmitate (0.2 %) and stearate (0.1 %).</p>

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

<p>Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.</p>

<p>Lipase 14 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 30-40°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 14 was shown to hydrolyze p-Nitrophenyl esters of butyrate (74 % activity compared to octanoate), octanoate (100 %), laurate (8 %), palmitate (5 %), stearate (4 %), arachidate (1 %) and behenate (0.6 %).</p>

HSL-IN-5 (Example 21) is a hormone-sensitive lipase (HSL) inhibitor with an IC₅₀ value of 0.2 μM, suitable for diabetes research.

<p>Phospholipases D belong to the family of esterases and act on phosphatidylcholine in the plasma membrane to release phosphatidic acid (PA) and choline. Phospholipases D can be used as versatile tools in hydrolysis and transphosphatidylation reactions for industrial, chemical and food applications. The Phospholipase D Kit contains 4 enzymes with a broad pH range for transphosphatidylation activity.</p>

endothelial lipase and lipoprotein lipase inhibitor

HSL-IN-2 is a selective inhibitor of Hormone Sensitive Lipase (HSL; IC50: 0.023 μM).

NF-1819: strong, selective MGL inhibitor; eases MS symptoms; analgesic; penetrates brain with high permeability.

MAGL-IN-1 is a selective and potent monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 80 nM.

BemPPOX is a potent inhibitor of DGL.

SMP-028 is a neutral cholesterol esterase (CEase) inhibitor(IC50 : 1.01 μM).

HSL-IN-1 is an HSL inhibitor that significantly reduces the reactive metabolite load and reduces the release of free fatty acids from stored fat.

Esterastin is an Inhibitor of esterases.

1,3-Didecanoylglycerol, a saturated diacylglycerol, has decanoic acids at sn-1,3; used in lipid monolayer and lipase research.

Endothelial lipase inhibitor-1 is a potent endothelial lipase inhibitor with an IC50 of 49 nM.

JNJ-42226314 is a MAGL inhibitor with anti-injury effects and has shown efficacy in neuropathic pain and inflammatory pain models.

NG-497, a selective inhibitor of human ATGL, blocks lipolysis in adipocytes and aids cancer research.