PPAR
I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.
Trovati 164 prodotti di "PPAR"
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Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS:<p>Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.</p>Formula:C24H23NO5SPurezza:99.59%Colore e forma:SoildPeso molecolare:437.51MCC-555
CAS:<p>MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.</p>Formula:C21H16FNO3SPurezza:99.07% - 99.82%Colore e forma:SolidPeso molecolare:381.42PPAR agonist 6
<p>PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].</p>Colore e forma:Odour SolidPPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Formula:C23H28FN7O3Colore e forma:SolidPeso molecolare:469.51Anti-obesity agent 1
<p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>Formula:C21H22N2O6Colore e forma:SolidPeso molecolare:398.409CUDA
CAS:<p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>Formula:C19H36N2O3Purezza:97.585%Colore e forma:SolidPeso molecolare:340.58-iso Prostaglandin F1β
CAS:<p>8-iso Prostaglandin F1β,inducet vasoconstrictor effects in (PA), (PV) and (MA) through the activation of TXA2R, tyrosine kinase and Rho kinase.</p>Formula:C20H36O5Colore e forma:SolidPeso molecolare:356.5Sulotroban
CAS:<p>sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.</p>Formula:C16H17NO5SPurezza:98.86% - 99.88%Colore e forma:SolidPeso molecolare:335.37CC618
CAS:<p>CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.</p>Formula:C20H15F6N3O3S2Purezza:99.94%Colore e forma:SolidPeso molecolare:523.47Anti-osteoporosis agent-10
<p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>Colore e forma:Odour SolidLipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Colore e forma:Odour SolidWAY-620472
CAS:<p>WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.</p>Formula:C23H21N5OSPurezza:98.07%Colore e forma:SolidPeso molecolare:415.51AZD-9574
CAS:<p>AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.</p>Formula:C21H22F2N6O2Purezza:98.46% - 99.39%Colore e forma:SolidPeso molecolare:428.44PPAR α/PPARA Protein, Human, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.</p>Colore e forma:Lyophilized PowderPeso molecolare:31.36 kDa (predicted)PPAR α/PPARA Protein, Mouse, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.</p>Colore e forma:Lyophilized PowderPeso molecolare:31.49 kDa (predicted)Balaglitazone
CAS:<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Formula:C20H17N3O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:395.43CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Formula:C26H33NO5Purezza:99.84%Colore e forma:SolidPeso molecolare:439.54GW0742
CAS:<p>GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).</p>Formula:C21H17F4NO3S2Purezza:99.75% - 99.85%Colore e forma:SolidPeso molecolare:471.49Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Formula:C22H28ClNO5Purezza:98.82%Colore e forma:SolidPeso molecolare:421.91MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formula:C27H34ClNO2SPurezza:99.23% - 99.84%Colore e forma:SolidPeso molecolare:472.08
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