Reduttasi HMG-CoA
La HMG-CoA reduttasi è un enzima chiave nella via del mevalonato, responsabile della sintesi del colesterolo e di altri isoprenoidi. Gli inibitori della HMG-CoA reduttasi, comunemente noti come statine, sono ampiamente utilizzati per abbassare i livelli di colesterolo e ridurre il rischio di malattie cardiovascolari. Questi inibitori hanno anche potenziali benefici nella ricerca sul cancro e sulle malattie neurodegenerative. Presso CymitQuimica, offriamo una varietà di inibitori della HMG-CoA reduttasi per supportare la tua ricerca nel metabolismo lipidico, nella salute cardiovascolare e nello sviluppo terapeutico.
Trovati 33 prodotti di "Reduttasi HMG-CoA"
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Atorvastatin lactone
CAS:Atorvastatin lactone is a prodrug form of atorvastatin. Which is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.Formula:C33H33FN2O4Purezza:98.05% - 98.16%Colore e forma:SolidPeso molecolare:540.62Lipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Colore e forma:Odour SolidGanoderenic acid K
CAS:<p>Ganoderenic acid K, from Ganoderma lucidum, inhibits HMG-CoA reductase with an IC50 of 16.5 μM.</p>Formula:C32H44O9Colore e forma:SolidPeso molecolare:572.69HMG-CoA Reductase-IN-1
HMG-CoA Reductase-IN-1 is an inhibitor of HMG-CoA reductase, demonstrating strong inhibitory activity on HMGR and affinity for OATP1B1, with pIC50 and pKmFormula:C27H29N3O7Colore e forma:SolidPeso molecolare:507.54(Rac)-5-Keto Fluvastatin
CAS:(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.Formula:C24H24FNO4Purezza:95.04%Colore e forma:SolidPeso molecolare:409.45(3S,5R)-Fluvastatin D6 sodium
CAS:(3S,5R)-Fluvastatin D6 sodium: deuterium-labeled synthetic HMG-CoA reductase inhibitor with 8 nM IC50.Formula:C24H25FNNaO4Purezza:98%Colore e forma:SolidPeso molecolare:439.49Rawsonol
CAS:Rawsonol is a HMG-CoA reductase inhibitor from the tropical green alga Avrainvillea rawsoni.Formula:C29H24Br4O7Colore e forma:SolidPeso molecolare:804.11L 645164
CAS:L 645164 is an inhibitor of hydroxymethylglutaryl-CoA reductase.Formula:C22H23FO3Colore e forma:SolidPeso molecolare:354.4124,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Formula:C27H44O2Peso molecolare:400.64Rosuvastatin Sodium
CAS:Rosuvastatin Sodium (ZD4522 Sodium) is a competitive HMG-CoA reductase (HMGCR) inhibitor (IC50=11 nM) with lipid-lowering and anti-atherosclerotic effects.Formula:C22H27FN3NaO6SColore e forma:SolidPeso molecolare:503.52Pravastatin lactone
CAS:<p>Pravastatin lactone, a non-enzymatic stomach derivative of pravastatin, inhibits HMG-CoA reductase and stems from mevastatin.</p>Formula:C23H34O6Colore e forma:SolidPeso molecolare:406.519Atorvastatin calcium trihydrate
CAS:Atorvastatin is used to inhibits HMG-CoA reductase for lowering blood cholesterol and for prevention of events associated with cardiovascular disease.Formula:C66H74CaF2N4O13Colore e forma:SolidPeso molecolare:1209.39PPD 10558
CAS:PPD 10558, a HMG-CoA reductase inhibitor, is used potentially for treatment of primary hypercholesterolemia.Formula:C34H37FN2O6Colore e forma:SolidPeso molecolare:588.677-Ketocholesterol
CAS:7-Ketocholesterol is a metabolite of CholesterolFormula:C27H44O2Purezza:97.59% - 98.84%Colore e forma:SolidPeso molecolare:400.65Tenivastatin
CAS:Tenivastatin (Simvastatin acid) is an anti-hyperlipidemic HMG-CoA reductase inhibitor used in the study of primary hyperlipidemia.Formula:C25H40O6Purezza:99.56%Colore e forma:SolidPeso molecolare:436.58Simvastatin acid ammonium
CAS:Simvastatin acid ammonium (Tenivastatin ammonium) is an HMG-CoA reductase (HMGCR) inhibitor.Formula:C25H43NO6Purezza:98.3%Colore e forma:SolidPeso molecolare:453.61Pravastatin
CAS:Pravastatin (CS-514) is a competitive HMG-CoA reductase inhibitor with an IC50 of 5.6 μM for sterol synthesis, capable of lowering serum cholesterol.Formula:C23H36O7Purezza:99.99%Colore e forma:White PowderPeso molecolare:424.534-Acetylsimvastatin
CAS:<p>4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).</p>Formula:C27H40O6Purezza:98%Colore e forma:SolidPeso molecolare:460.6(3S,5R)-Pitavastatin calcium
CAS:(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Formula:C25H26CaFNO4Purezza:98%Colore e forma:SolidPeso molecolare:463.562(3S,5S)-Pitavastatin calcium
CAS:(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Formula:C25H26CaFNO4Purezza:98%Colore e forma:SolidPeso molecolare:463.562Lovastatin hydroxy acid sodium
CAS:<p>Lovastatin Sodium is an HMG-CoA reductase inhibitor.</p>Formula:C24H38NaO6Colore e forma:SolidPeso molecolare:445.54(3S,5R)-Fluvastatin sodium
CAS:(3S,5R)-Fluvastatin sodium: synthetic HMG-CoA reductase inhibitor, IC50 8 nM, boosts vascular cell antioxidant defense.Formula:C24H26FNNaO4Purezza:98%Colore e forma:SolidPeso molecolare:434.463L 669262
CAS:L 669262 is a potent inhibitor of HMG-CoA reductase.Formula:C25H36O6Colore e forma:SolidPeso molecolare:432.55Simvastatin acid calcium hydrate
CAS:Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.Formula:C25H40O6Colore e forma:SolidPeso molecolare:436.28249Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Formula:C14H23NO3Purezza:98.69% - 99.54%Colore e forma:SolidPeso molecolare:253.342'-Ethyl Simvastatin
CAS:2'-Ethyl Simvastatin is a Mevinolin analog with HMG-CoA reductase inhibition.Formula:C23H34O5Purezza:98%Colore e forma:SolidPeso molecolare:390.51(Z)-Pitavastatin calcium
CAS:(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.Formula:C50H50CaF2N2O8Purezza:98%Colore e forma:SolidPeso molecolare:885.031Dalvastatin
CAS:Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepaticFormula:C24H31FO3Purezza:98.07%Colore e forma:SolidPeso molecolare:386.5(3R,5R)-Rosuvastatin calcium
CAS:(3R,5R)-Rosuvastatin, a potential impurity detected in bulk rosuvastatin formulations, arises as a degradation product through various stresses including acid or base hydrolysis, thermal, photolytic, hydrolytic, oxidative stress, or during storage. This compound is associated with the HMG-CoA reductase inhibitor class to which rosuvastatin belongs.Formula:C22H28FN3O6SCaColore e forma:SolidPeso molecolare:500.6Rosuvastatin zinc salt
CAS:Rosuvastatin zinc salt (Rosuvastatin zinc), a zinc-infused variant of Rosuvastatin, functions as an HMG-CoA reductase inhibitor, utilized primarily inFormula:C44H54F2N6O12S2ZnColore e forma:SolidPeso molecolare:1026.47QH536
CAS:QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.Formula:C33H49N3O3Colore e forma:SolidPeso molecolare:535.76Bemfivastatin hemicalcium
CAS:Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.Formula:C34H36FN2O6CaColore e forma:SolidPeso molecolare:607.67L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Formula:C19H30O5Purezza:98%Colore e forma:SolidPeso molecolare:338.44
