Transferasi
Le transferasi sono una grande classe di enzimi che catalizzano il trasferimento di gruppi funzionali, come gruppi metile, glicosile e fosfato, da una molecola all'altra. Gli inibitori delle transferasi sono utilizzati per studiare un'ampia gamma di processi biologici, tra cui la trasduzione del segnale, il metabolismo e l'espressione genica. Questi inibitori sono strumenti essenziali in ambiti di ricerca come il cancro, le malattie metaboliche e l'epigenetica, dove è implicata una disfunzione dell'attività delle transferasi. Presso CymitQuimica offriamo una selezione completa di inibitori delle transferasi per supportare la tua ricerca in enzimologia, segnalazione cellulare e meccanismi patologici.
Trovati 37 prodotti per "Transferasi".
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Nitecapone
CAS:Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)Formula:C12H11NO6Purezza:98.39%Colore e forma:SolidPeso molecolare:265.223-O-Methyltolcapone
CAS:3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.Formula:C15H13NO5Purezza:98%Colore e forma:SolidPeso molecolare:287.27PDMP hydrochloride
CAS:PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.Formula:C23H39ClN2O3Colore e forma:SolidPeso molecolare:427.03P-3FAX-Neu5Ac
CAS:P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.Formula:C22H30FNO14Purezza:97.08%Colore e forma:White SolidPeso molecolare:551.47Lucerastat
CAS:Lucerastat（NBDGJ） is an orally available inhibitor of GCS for Fabry disease by reducing harmful substrates.. GCS is a key enzyme in sphingolipid synthesiss.Formula:C10H21NO4Purezza:98%Colore e forma:White SolidPeso molecolare:219.28Prenyl-IN-1
CAS:Prenyl-IN-1 inhibits prenylation selectively, counters oxidative stress in Parkinson's.Formula:C28H24ClN5O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:497.98α-2,3-sialyltransferase-IN-1
CAS:α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).Formula:C28H45NO6Purezza:98% - 98%Colore e forma:Transparent LiquidPeso molecolare:491.66Lith-O-Asp
CAS:Lith-O-Asp is a sialyltransferase inhibitor; Ki=1.3 μM; reduces sialylation; inhibits cancer cell invasion; metastasis research.Formula:C28H45NO6Colore e forma:White SolidPeso molecolare:491.66Ibiglustat (L-Malic acid)
CAS:Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase.Formula:C24H30FN3O7SPurezza:99.54%Colore e forma:SolidPeso molecolare:523.57Ref: TM-T11599
1mg37,00€2mg50,00€5mg96,00€1mL*10mM (DMSO)100,00€10mg128,00€25mg208,00€50mg310,00€100mg444,00€200mg618,00€Miglustat hydrochloride
CAS:Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I GaucherFormula:C10H22ClNO4Purezza:99.85%Colore e forma:SolidPeso molecolare:255.74Ref: TM-TQ0155
1mg38,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg245,00€50mg385,00€100mg557,00€200mg790,00€FGTI-2734
CAS:FGTI-2734, a dual FT/GGT-1 inhibitor (IC50: 250/520 nM), blocks KRAS membrane binding and curbs KRAS-driven pancreatic cancer.Formula:C26H31FN6O2SPurezza:99.69%Colore e forma:SolidPeso molecolare:510.63Ref: TM-T11282
1mg49,00€5mg113,00€1mL*10mM (DMSO)129,00€10mg178,00€25mg371,00€50mg557,00€100mg792,00€OSMI-1
CAS:OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.Formula:C28H25N3O6S2Purezza:96.79% - 99.66%Colore e forma:White SolidPeso molecolare:563.64Glucosylceramide synthase-IN-4
CAS:Glucosylceramide Synthase-IN-4 (compound 12) serves as a potent inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 of 6.8 nM. It demonstrates superior pharmacokinetic properties and robust stability in human hepatocytes. Additionally, this compound is noted for its effective CNS penetration and acceptable PXR selectivity [1].Formula:C22H18F5N3O3Colore e forma:SolidPeso molecolare:467.39PF-07202954
CAS:PF-07202954 is a DGAT2 inhibitor with a long half-life. reduce the triglyceride content in the liver of rats fed with a Western diet, NASH.Formula:C22H23FN6O3Purezza:98.99%Colore e forma:Yellow SolidPeso molecolare:438.45ICMT-IN-55
CAS:ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].Formula:C22H26F3NO2Colore e forma:SolidPeso molecolare:393.44BMS-214662 mesylate
CAS:BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.Formula:C26H27N5O5S3Colore e forma:SolidPeso molecolare:585.718Darlifarnib
CAS:Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.Formula:C29H20N6OColore e forma:SolidPeso molecolare:468.509
