Sintasi degli acidi grassi
La sintasi degli acidi grassi (FAS) è un complesso multi-enzimatico responsabile della sintesi degli acidi grassi a catena lunga. La sovraespressione di FAS è associata a vari disturbi metabolici, tra cui obesità, diabete e cancro. L'inibizione di FAS può ridurre la biosintesi lipidica e indurre apoptosi nelle cellule tumorali, rendendola un obiettivo promettente per la terapia del cancro e la ricerca sulle malattie metaboliche. Presso CymitQuimica, offriamo una varietà di inibitori di FAS per supportare la tua ricerca in oncologia, metabolismo e sviluppo terapeutico.
Trovati 38 prodotti di "Sintasi degli acidi grassi"
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FT113
CAS:FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFormula:C22H20FN3O4Purezza:97.05%Colore e forma:SolidPeso molecolare:409.41PF 429242
CAS:<p>PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).</p>Formula:C25H35N3O2Purezza:99.27%Colore e forma:SolidPeso molecolare:409.56TVB-3664
CAS:TVB-3664 is an orally active, selective, highly bioavailable fatty acid synthase inhibitor (FASN).Cost-effective and quality-assured.Formula:C25H23F3N4O2Purezza:99.17% - 99.64%Colore e forma:SolidPeso molecolare:468.47Fatostatin
CAS:Fatostatin inhibits SREBP-1/2 by binding to SCAP, blocking their ER-Golgi transport.Formula:C18H18N2SPurezza:99.92%Colore e forma:SolidPeso molecolare:294.41VY-3-135
CAS:<p>VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor.Cost-effective and quality-assured.</p>Formula:C26H27N3O3Purezza:99.25% - 99.79%Colore e forma:SolidPeso molecolare:429.51HS80
CAS:HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).Formula:C19H22N4SPurezza:98%Colore e forma:SolidPeso molecolare:338.47FASN-IN-5
CAS:FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.Formula:C29H26N4O2Purezza:99.88%Colore e forma:SolidPeso molecolare:462.54FASN-IN-4
CAS:FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.Formula:C26H27N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:477.58HS79
CAS:HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.Formula:C19H22N4SPurezza:98%Colore e forma:SolidPeso molecolare:338.47Malic enzyme inhibitor ME1
CAS:Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.Formula:C20H21N3O3Purezza:99.84%Colore e forma:SolidPeso molecolare:351.4C75
CAS:C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).Formula:C14H22O4Purezza:98.84% - >99.99%Colore e forma:SolidPeso molecolare:254.32SREBP/SCAP-IN-2
CAS:SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].Formula:C27H37ClF2N4OColore e forma:SolidPeso molecolare:507.061,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol
CAS:1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to decrease hepatic triglyceride and cholesterol levels in mice.Formula:C57H98O6Colore e forma:SolidPeso molecolare:879.38FAS-IN-1 Tosylate
<p>FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.</p>Formula:C33H35N3O7S2Purezza:98%Colore e forma:SolidPeso molecolare:649.78SREBP/SCAP-IN-1
CAS:SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].Formula:C28H40F2N4OColore e forma:SolidPeso molecolare:486.64FASN-IN-1
CAS:FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzymeFormula:C18H25N3O3S2Purezza:99.92% - >99.99%Colore e forma:SolidPeso molecolare:395.54PFM046
CAS:<p>PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.</p>Formula:C29H42O2Colore e forma:SolidPeso molecolare:422.643ONL-1204
CAS:ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Formula:C71H100N18O16Colore e forma:SolidPeso molecolare:1461.66
