Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 303 prodotti di "Deidrogenasi"
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CB29
CAS:<p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>Formula:C15H15N3O5SPurezza:99.36%Colore e forma:SolidPeso molecolare:349.36PHGDH-IN-2
PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.Formula:C22H20N4O3SColore e forma:SolidPeso molecolare:420.48HSD17B13-IN-28
CAS:HSD17B13-IN-28 (compound 47) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with an IC50 of < 0.1 μM using estradiol as a substrate. HSD17B13-IN-28 plays an important role in nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].Formula:C23H16Cl2FN3O3Colore e forma:SolidPeso molecolare:472.317β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.Formula:C21H21NO3Colore e forma:SolidPeso molecolare:335.4BI-4916
CAS:BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formula:C23H24Cl2N2O6SPurezza:98.55%Colore e forma:SolidPeso molecolare:527.42HSD17B13-IN-32
CAS:HSD17B13-IN-32 (Compound 67) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤0.1 μM for estradiol. It can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].Formula:C23H15Cl2N5O3Peso molecolare:480.3HSD17B13-IN-40
CAS:HSD17B13-IN-40 (compound 6) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM using estradiol as substrates. This compound is significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formula:C23H14Cl2F3N3O3Peso molecolare:508.28hDHODH-IN-10
hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.Formula:C21H15ClF4N2O4Colore e forma:SolidPeso molecolare:470.811β-HSD2-IN-2
CAS:<p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>Formula:C22H21NO2Purezza:99.61%Colore e forma:SolidPeso molecolare:331.41DSM705 hydrochloride
DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.Formula:C19H20ClF3N6OColore e forma:SolidPeso molecolare:440.85Deamino-NAD sodium
CAS:Deamino-NAD sodium, a structural analog of NAD+, serves as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH) in glycolysis. It exhibits a Km of 2300 pm and a Kd of 112 pm.Formula:C21H25N6NaO15P2Colore e forma:SolidPeso molecolare:686.39HSD17B13-IN-95
CAS:HSD17B13-IN-95 (1) serves as an inhibitor for 17 β-hydroxysteroid dehydrogenase (HSD17B13), exhibiting an IC50 value of <0.1 μM for estradiol. It is applicable in researching nonalcoholic fatty liver disease [1].Formula:C24H16F6N4O4Peso molecolare:538.40PDHK-IN-4
PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.Formula:C24H25N5O3Colore e forma:SolidPeso molecolare:431.49BRD7539
CAS:BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.Formula:C23H22FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:391.44Oxamic acid
CAS:Oxamic acid is an LDHA inhibitor, antitumor, induces apoptosis, downregulates EGFR expression, and inhibits cancer stem cell properties and EMT.Formula:C2H3NO3Colore e forma:SolidPeso molecolare:89.05Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Colore e forma:SolidPeso molecolare:454.56RORγt/DHODH-IN-1
CAS:RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significantFormula:C24H26ClF6N3O3SColore e forma:SolidPeso molecolare:585.99HSD17B13-IN-19
CAS:HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].Formula:C23H23FN2O4SPeso molecolare:442.5AKR1C3-IN-8
AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.Formula:C23H20N4O3Colore e forma:SolidPeso molecolare:400.43AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.Formula:C24H20N2O4Colore e forma:SolidPeso molecolare:400.43
