Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
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hDHODH-IN-16
hDHODH-IN-16 (Compound 3t) is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an IC50 of 0.11 μM. It demonstrates very low cytotoxicity towards healthy HaCaT cells, with an IC50 value exceeding 200 μM.Formula:C18H20N2O2Colore e forma:SolidPeso molecolare:296.36hDHODH-IN-13
CAS:hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inColore e forma:SoildMTHFD2-IN-1
<p>MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].</p>Formula:C24H21NO6Colore e forma:SolidPeso molecolare:419.43KOTX1
CAS:KOTX1 is an orally active and selective inhibitor of ALDH1A3. In a diabetic mouse model, KOTX1 improves glucose tolerance, insulin secretion, and blood glucose levels.Formula:C17H16FN3O2Colore e forma:SolidPeso molecolare:313.33MCI-INI-3
CAS:MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.Formula:C21H15N3O4Colore e forma:SolidPeso molecolare:373.36(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Formula:C21H27NO3Purezza:98%Colore e forma:SolidPeso molecolare:341.44Osmanthuside H
CAS:Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.Formula:C19H28O11Colore e forma:SolidPeso molecolare:432.422D-Lactate dehydrogenase
CAS:D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Colore e forma:Solid18β-Glycyrrhetyl-3-O-sulfate
CAS:18β-Glycyrrhetyl-3-O-sulfate (Glycyrrhetic acid 3-O-(hydrogen sulfate)), a major metabolite of Glycyrrhetinic acid (GA), serves as a potent inhibitor of type 2Formula:C30H46O7SColore e forma:SolidPeso molecolare:550.75DHODH-IN-23
CAS:<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formula:C24H21ClFNO4Purezza:99.7%Colore e forma:SolidPeso molecolare:441.88CM121
CAS:CM121, a reversible ALDH1A2 inhibitor, targets active site with IC50=0.54μM, Kd=1.1μM, using hydrophobic interactions.Formula:C24H17FN4O3SColore e forma:SolidPeso molecolare:460.48BVT-2733 hydrochloride
CAS:BVT-2733 hydrochloride is a potent, selective, and orally active non-steroidal 11β-HSD1 inhibitor. It exhibits stronger inhibition on mouse 11β-HSD1 enzyme (IC50=96 nM) compared to the human 11β-HSD1 enzyme (IC50=3341 nM). BVT-2733 hydrochloride shows potential for research in arthritis and obesity-related diseases.Formula:C17H22Cl2N4O3S2Colore e forma:SolidPeso molecolare:465.42IGUANA-1 free base
CAS:IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Formula:C26H24ClN3O2Colore e forma:SolidPeso molecolare:445.9411β-HSD1-IN-11
CAS:11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Formula:C15H11F3O3SPurezza:99.61%Colore e forma:SoildPeso molecolare:328.31Ref: TM-T60149
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€1mL*10mM (DMSO)251,00€D34-919
CAS:D34-919 is a potent inhibitor of the ALDH1A3-PKM2 interaction, effectively inhibiting the ALDH1A3-mediated tetramerization enhancement of PKM2. Treatment mediated by D34-919 both in vitro and in vivo enhances and restores apoptosis and sensitivity in glioblastoma (GBM) cells induced by radiochemotherapy.Formula:C22H27N5OSPeso molecolare:409.55PDK-IN-1
CAS:PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formula:C20H16BrN7OColore e forma:SolidPeso molecolare:450.294-Isopropoxybenzaldehyde
CAS:ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.Formula:C10H12O2Purezza:99.00%Colore e forma:SolidPeso molecolare:164.2Aldehyde dehydrogenase (NAD(P))
CAS:<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Colore e forma:SolidPKUMDL-WQ-2201
CAS:PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.Formula:C15H14ClN3O3SColore e forma:SolidPeso molecolare:351.81PS10
CAS:PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.Formula:C14H13NO6SPurezza:99.01%Colore e forma:SolidPeso molecolare:323.32
