Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
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Metapramine
CAS:Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.Formula:C16H18N2Purezza:99.03% - 99.67%Colore e forma:SolidPeso molecolare:238.33DHODH-IN-15
CAS:DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.Formula:C15H11N3O3Purezza:99.8%Colore e forma:SolidPeso molecolare:281.27Ref: TM-T11024
1mg109,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€200mg1.378,00€1mL*10mM (DMSO)225,00€hDHODH-IN-5
CAS:hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Formula:C21H21F3N2O2Purezza:99.55%Colore e forma:SolidPeso molecolare:390.4Ref: TM-T11029
1mg85,00€5mg166,00€10mg234,00€25mg376,00€50mg560,00€100mg797,00€1mL*10mM (DMSO)175,00€11β-HSD1-IN-12
CAS:11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFormula:C19H27ClN2O3SPurezza:99.89%Colore e forma:SolidPeso molecolare:398.95M77976
CAS:M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.Formula:C17H16N2O3Purezza:99.92%Colore e forma:SolidPeso molecolare:296.32p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Formula:C11H14O2Purezza:99.87%Colore e forma:White To Light Beige PowderPeso molecolare:178.23EN40
CAS:EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).Formula:C13H15NO2Colore e forma:SolidPeso molecolare:217.26Genz-669178
CAS:Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).Formula:C17H14N4OSPurezza:98%Colore e forma:SolidPeso molecolare:322.38hDHODH-IN-9
CAS:hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.Formula:C21H21NO4Colore e forma:SolidPeso molecolare:351.4KM04416
CAS:KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Formula:C12H11NO3SPurezza:99.88%Colore e forma:SolidPeso molecolare:249.29AGI-14100
CAS:AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
Formula:C29H22ClF4N5O3Purezza:99.91%Colore e forma:SolidPeso molecolare:599.96ALDH1A1-IN-3
CAS:ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.Formula:C31H36F3N5O4Colore e forma:SolidPeso molecolare:599.64DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Formula:C24H25F4N3O3Colore e forma:SolidPeso molecolare:479.47RORγt/DHODH-IN-2
CAS:RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).Formula:C25H30N4OSColore e forma:SolidPeso molecolare:434.6RS6212
CAS:RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.
Formula:C20H22N4O3SColore e forma:SolidPeso molecolare:398.48SCH-451659
CAS:SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.Formula:C30H39Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:544.56NCT-506
CAS:NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).Formula:C25H23FN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:478.54PHGDH-IN-3
CAS:PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.Formula:C24H18FN3O4S2Purezza:97.24% - 99.1%Colore e forma:SolidPeso molecolare:495.55HSD-016
CAS:HSD-016: Oral 11β-HSD1 inhibitor, active in humans, mice, rats (IC50: 11, 1, 8 nM), potential for type 2 diabetes research.Formula:C21H21F7N2O3SPurezza:99.40% - >99.99%Colore e forma:SolidPeso molecolare:514.46Ref: TM-T63569
1mg84,00€5mg280,00€10mg439,00€25mg888,00€50mg1.485,00€100mg2.358,00€1mL*10mM (DMSO)310,00€CPS-11
CAS:CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.Formula:C14H12N2O5Purezza:99.8% - 99.98%Colore e forma:SolidPeso molecolare:288.26CM037
CAS:CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminateFormula:C21H25N3O3S2Purezza:99.77%Colore e forma:SolidPeso molecolare:431.57hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formula:C21H23FN4OPurezza:99.87%Colore e forma:SolidPeso molecolare:366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)266,00€PKUMDL-WQ-2101
CAS:PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.Formula:C14H11N3O6Purezza:99.57%Colore e forma:SolidPeso molecolare:317.25Qc1
CAS:Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.Formula:C23H16F3N3O2SPurezza:99.75%Colore e forma:SolidPeso molecolare:455.45IGP-1
CAS:iGP-1 is a cell-permeable mitochondrial sn-Glycerol 3-phosphate dehydrogenase (mGPDH) inhibitor.Formula:C17H15N3O3Purezza:99.12% - 99.15%Colore e forma:SolidPeso molecolare:309.32Ref: TM-T25526
2mg35,00€5mg52,00€10mg74,00€25mg133,00€50mg202,00€100mg321,00€200mg469,00€1mL*10mM (DMSO)88,00€DSM421
CAS:DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shownFormula:C14H11F5N6Purezza:99.67% - 99.82%Colore e forma:SolidPeso molecolare:358.27Ref: TM-T27214
1mg116,00€5mg273,00€10mg373,00€25mg563,00€50mg758,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)319,00€DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Formula:C28H31F3N4O6SPurezza:98.19% - >99.99%Colore e forma:SolidPeso molecolare:608.63Ref: TM-T11103
1mg109,00€5mg260,00€10mg409,00€25mg737,00€50mg1.198,00€100mg1.611,00€1mL*10mM (DMSO)358,00€IDH2R140Q-IN-2
CAS:IDH2R140Q-IN-2 is an IDH2R140Q inhibitor indicated for the study of acute myeloid leukaemia (AML).Formula:C21H18F6N6OPurezza:99.92%Colore e forma:SolidPeso molecolare:484.4BMS-823778
CAS:BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.Formula:C18H18ClN3OPurezza:99.39% - 99.75%Colore e forma:SolidPeso molecolare:327.81Ref: TM-T71394
1mg167,00€2mg246,00€5mg411,00€10mg562,00€25mg867,00€50mg1.121,00€100mg1.425,00€200mg1.882,00€ALDH1A3-IN-2
CAS:ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.Formula:C13H17NOPurezza:99.84%Colore e forma:SolidPeso molecolare:203.28G6PD activator AG1
CAS:G6PD activator AG1 is a G6PD agonist that promotes G6PD oligomerization to a catalytically competent form.Formula:C24H30N4S2Purezza:98.38% - 99.51%Colore e forma:SolidPeso molecolare:438.65PBRM
CAS:PBRM (17β-HSD1-IN-2) is a selective covalent inhibitor of 17β-HSD1, used in breast cancer and endometriosis research.Formula:C28H34BrNO2Purezza:99.56% - 99.59%Colore e forma:SolidPeso molecolare:496.48Olorofim
CAS:Olorofim（F-901318）is a new selective antifungal compound that inhibits Aspergillus fumigatus DHODH (IC50: 44 nM). Cost-effective and quality-assured.Formula:C28H27FN6O2Purezza:99.28%Colore e forma:SolidPeso molecolare:498.55hDHODH-IN-1
CAS:hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.Formula:C17H14N2O2Purezza:99.97%Colore e forma:SolidPeso molecolare:278.31Ref: TM-T11546
1mg34,00€5mg71,00€10mg103,00€25mg200,00€50mg290,00€100mg404,00€200mg545,00€1mL*10mM (DMSO)78,00€11α-Hydroxyprogesterone
CAS:11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an effective dose (ED)50 of 10 nM.Formula:C21H30O3Colore e forma:SolidPeso molecolare:330.468PF-915275
CAS:PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.Formula:C18H14N4O2SPurezza:99.58% - 99.61%Colore e forma:SolidPeso molecolare:350.39Ref: TM-T16510
1mg38,00€2mg49,00€5mg81,00€10mg127,00€25mg255,00€50mg499,00€100mg723,00€500mg1.510,00€1mL*10mM (DMSO)89,00€Anticancer agent 121
CAS:Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].Formula:C19H18N2O3SColore e forma:SolidPeso molecolare:354.42GSK321
CAS:GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.Formula:C28H28FN5O3Purezza:99.73%Colore e forma:SolidPeso molecolare:501.5515-PGDH-IN-1
CAS:15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.Formula:C24H22N4O2Colore e forma:SolidPeso molecolare:398.46IDH1 Inhibitor 2
CAS:IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).Formula:C26H22N4OPurezza:98%Colore e forma:SolidPeso molecolare:406.48AZD 4017
CAS:AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).Formula:C22H33N3O3SPurezza:99.61%Colore e forma:SolidPeso molecolare:419.58Ref: TM-T14388
1mg73,00€5mg160,00€10mg274,00€25mg550,00€50mg792,00€100mg1.093,00€1mL*10mM (DMSO)170,00€HSD17B13-IN-2
CAS:HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1Formula:C21H23F2NO4Colore e forma:SolidPeso molecolare:391.41DHODH-IN-14
CAS:DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.Formula:C15H7F4N3O3Purezza:99.81%Colore e forma:SolidPeso molecolare:353.23Ref: TM-T11023
1mg109,00€2mg163,00€5mg243,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mgPrezzo su richiesta1mL*10mM (DMSO)250,00€HSD17B13-IN-3
CAS:HSD17B13-IN-3 (compound 2) is a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13), lacking cellular experimental activity [1].Formula:C22H21NO6S2Colore e forma:SolidPeso molecolare:459.54CHK-336
CAS:CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluriaFormula:C24H20F2N4O4S2Colore e forma:SolidPeso molecolare:530.57Anticancer agent 122
CAS:Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use inFormula:C18H15ClN2O2SColore e forma:SolidPeso molecolare:358.84MK-0736
CAS:MK-0736 is a potent and selective 11β-HSD-1 inhibitor.Formula:C23H30F3N3O2SColore e forma:SolidPeso molecolare:469.56IDH889
CAS:IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).Formula:C23H25FN6O2Purezza:≥98%Colore e forma:SolidPeso molecolare:436.4815-PGDH-IN-2
CAS:15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].Formula:C16H13NO3S2Colore e forma:SolidPeso molecolare:331.41YG1702
CAS:YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.Formula:C23H30N2O7SColore e forma:SolidPeso molecolare:478.56DHODH-IN-22
CAS:DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.Formula:C21H21ClF4N6O5Colore e forma:SolidPeso molecolare:548.88Tetrahydro-11-dehydrocorticosterone
CAS:Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].Formula:C21H32O4Colore e forma:SolidPeso molecolare:348.48AKR1C3-IN-6
CAS:AKR1C3-IN-6: Strong AKR1C3 inhibitor (IC50: 0.31 μM); weak on AKR1C2 (IC50: 73.23 μM); shows antitumor effects.Formula:C18H15F3N4O3Colore e forma:SolidPeso molecolare:392.33S07-1066
CAS:S07-1066, an aldo-keto reductase 1C3 (AKR1C3) inhibitor, enhances doxorubicin (DOX) cytotoxicity by selectively inhibiting AKR1C3-mediated reduction of DOX andFormula:C16H11Cl2FO2Purezza:98%Colore e forma:SolidPeso molecolare:325.16MK-0736 hydrochloride
CAS:MK-0736 hydrochloride is a potent and selective 11β-HSD-1 inhibitor.Formula:C23H31ClF3N3O2SColore e forma:SolidPeso molecolare:506.03α-Pyridoin
CAS:α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.Formula:C12H12N2O2Colore e forma:SolidPeso molecolare:216.24KB-74935
CAS:KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.Formula:C19H18ClF4N3O3SPurezza:99.4%Colore e forma:SolidPeso molecolare:479.88CB29
CAS:CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).
Formula:C15H15N3O5SPurezza:99.36%Colore e forma:SolidPeso molecolare:349.36ALDH2 modulator 1
CAS:ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.
Formula:C18H18ClFN2O3Purezza:99.68%Colore e forma:SoildPeso molecolare:364.8BI-3231
CAS:BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.Formula:C16H14F2N4O3SPurezza:98.2%Colore e forma:SolidPeso molecolare:380.37Ref: TM-T73446
1mg69,00€5mg147,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€200mg982,00€1mL*10mM (DMSO)164,00€RORγt/DHODH-IN-1
CAS:RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significantFormula:C24H26ClF6N3O3SColore e forma:SolidPeso molecolare:585.99Indoluidin E
Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.Formula:C28H30N4O2Colore e forma:SolidPeso molecolare:454.56HSD17B13-IN-40
CAS:HSD17B13-IN-40 (compound 6) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of less than 0.1 μM using estradiol as substrates. This compound is significant in the treatment of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formula:C23H14Cl2F3N3O3Colore e forma:SolidPeso molecolare:508.28PDHK-IN-4
PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.Formula:C24H25N5O3Colore e forma:SolidPeso molecolare:431.49DSM705 hydrochloride
DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.Formula:C19H20ClF3N6OColore e forma:SolidPeso molecolare:440.85hDHODH-IN-10
hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.Formula:C21H15ClF4N2O4Colore e forma:SolidPeso molecolare:470.8Oxamic acid
CAS:Oxamic acid is an LDHA inhibitor, antitumor, induces apoptosis, downregulates EGFR expression, and inhibits cancer stem cell properties and EMT.Formula:C2H3NO3Colore e forma:SolidPeso molecolare:89.05PHGDH-IN-2
PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.Formula:C22H20N4O3SColore e forma:SolidPeso molecolare:420.48BRD7539
CAS:BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.Formula:C23H22FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:391.447-Hydroxy-4-phenylcoumarin
CAS:7-Hydroxy-4-phenylcoumarin is a dual inhibitor of ALDH-2 and MAO, with IC50 values of 1.5 µM and 0.5 µM, respectively.Formula:C15H10O3Colore e forma:SolidPeso molecolare:238.238Mirivadelgat
CAS:Mirivadelgat is an activator of aldehyde dehydrogenase 2 (aldehyde dehydrogenase2). It is anticipated to be useful in research related to interstitial lung disease, pulmonary arterial hypertension, and cancer.Formula:C30H34FN3O5Colore e forma:SolidPeso molecolare:535.607RORγt/DHODH-IN-3
RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 hasFormula:C24H26ClF6N3O3SColore e forma:SolidPeso molecolare:585.99HSD17B13-IN-95
CAS:HSD17B13-IN-95 (1) serves as an inhibitor for 17 β-hydroxysteroid dehydrogenase (HSD17B13), exhibiting an IC50 value of <0.1 μM for estradiol. It is applicable in researching nonalcoholic fatty liver disease [1].Formula:C24H16F6N4O4Peso molecolare:538.40BI-4916
CAS:BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.Formula:C23H24Cl2N2O6SPurezza:98.55%Colore e forma:SolidPeso molecolare:527.42FXR/HSD17B13 modulator 1
CAS:FXR/HSD17B13 modulator 1 (compound 6) is an effective modulator of FXR/HSD17B13, playing a significant role in studies related to metabolic dysfunction-associated steatohepatitis (MASH).Formula:C26H19Cl2NO4Colore e forma:SolidPeso molecolare:480.339AXKO-0046
AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.Formula:C25H33N3Colore e forma:SolidPeso molecolare:375.55LDHA-IN-5
CAS:LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primaryFormula:C27H22FN7O6S3Colore e forma:SolidPeso molecolare:655.7PDHK-IN-3
PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].Formula:C17H16N2O2Colore e forma:SolidPeso molecolare:280.3215-epi-PGE1
CAS:15-epi-PGE1 (15R-Prostaglandin E1; 15-Epiprostaglandin E1), a stereoisomer of PGE1, exhibits reduced biological activity [2]. This compound acts as a non-competitive inhibitor of human placental 15-Hydroxyprostaglandin dehydrogenase (15-PGDH), with an inhibitory concentration 50 (IC50) value of 170 μM [1].Formula:C20H34O5Colore e forma:SolidPeso molecolare:354.48T-3764518
CAS:T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).Formula:C20H17F6N5O2Purezza:98%Colore e forma:SolidPeso molecolare:473.37MDH1/2-IN-1
CAS:MDH1/2-IN-1 is an MDH1/2 inhibitor with IC50 values of 1.07 nM and 1.06 nM, respectively. It suppresses mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 exhibits significant antitumor potential and offers new avenues for developing drugs targeting cancer metabolism.Formula:C25H33NO4Colore e forma:SolidPeso molecolare:411.53411β-HSD2-IN-2
CAS:11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.Formula:C22H21NO2Purezza:99.61%Colore e forma:SolidPeso molecolare:331.41PDHK-IN-5
PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.Formula:C30H31N5O2Colore e forma:SolidPeso molecolare:493.6Deamino-NAD sodium
CAS:Deamino-NAD sodium, a structural analog of NAD+, serves as a substrate for rabbit muscle glyceraldehyde 3-phosphate dehydrogenase (GPDH) in glycolysis. It exhibits a Km of 2300 pm and a Kd of 112 pm.Formula:C21H25N6NaO15P2Colore e forma:SolidPeso molecolare:686.39AKR1C3-IN-7
AKR1C3-IN-7 (Compound 13) is an effective and selective AKR1C3 inhibitor (IC50=0.19 μM). AKR1C3-IN-7 has antitumor activity.Formula:C24H20N2O4Colore e forma:SolidPeso molecolare:400.43AKR1C3-IN-8
AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.Formula:C23H20N4O3Colore e forma:SolidPeso molecolare:400.43(6S)-CP-470711
CAS:(6S)-CP-470711 (Compound 8) acts as an inhibitor of sorbitol dehydrogenase (SDH) in both humans and rats, exhibiting inhibitory concentrations (IC50) of 19 nM and 27 nM, respectively. Additionally, (6S)-CP-470711 has been shown to ameliorate diabetes in rats induced by Streptozotocin.Formula:C18H26N6O2Colore e forma:SolidPeso molecolare:358.44HSD17B13-IN-28
CAS:HSD17B13-IN-28 (compound 47) is a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), with an IC50 of < 0.1 μM using estradiol as a substrate. HSD17B13-IN-28 plays an important role in nonalcoholic fatty liver diseases (NAFLDs), including NASH (nonalcoholic steatohepatitis) [1].Formula:C23H16Cl2FN3O3Colore e forma:SolidPeso molecolare:472.3HSD17B13-IN-84
CAS:HSD17B13-IN-84 (182) serves as an inhibitor of 17β-Hydroxysteroid dehydrogenases (HSD17B13), exhibiting an IC50 of less than 0.1 μM for Estradiol. It is primarily utilized in the study of NAFLD (Nonalcoholic fatty liver diseases) [1].Formula:C19H12Cl2F3N3O3SPeso molecolare:490.2817β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.Formula:C21H21NO3Colore e forma:SolidPeso molecolare:335.4HSD17B13-IN-17
CAS:HSD17B13-IN-17 (compound 9) serves as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13). It demonstrates inhibitory efficacy with IC50 values of ＜0.1 μM for estradiol and ＜1 μM for Leukotriene B3 as substrates. This compound is significant in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formula:C20H16ClFN2O3SColore e forma:SolidPeso molecolare:418.87HSD17B13-IN-19
CAS:HSD17B13-IN-19 (compound 16) acts as a potent inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting IC50 values under 0.1 μM and under 1 μM when using estradiol and Leukotriene B3 as substrates, respectively. This compound is crucial in the treatment of nonalcoholic fatty liver diseases (NAFLDs), such as nonalcoholic steatohepatitis (NASH) [1].Formula:C23H23FN2O4SColore e forma:SolidPeso molecolare:442.5HSD17B13-IN-44
CAS:HSD17B13-IN-44 (Compound 23) functions as an inhibitor targeting hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), exhibiting an IC50 value of < 0.1 μM against estradiol. This compound is applicable in the study of liver diseases or metabolic disorders [1].Formula:C18H14FNO5S2Colore e forma:SolidPeso molecolare:407.44GSK864
CAS:GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).Formula:C30H31FN6O4Purezza:97.07%Colore e forma:SolidPeso molecolare:558.6HSD17B13-IN-32
CAS:HSD17B13-IN-32 (Compound 67) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤0.1 μM for estradiol. It can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].Formula:C23H15Cl2N5O3Colore e forma:SolidPeso molecolare:480.3Etamicastat
CAS:Etamicastat can be used in the research of cardiovascular diseases.Formula:C14H15F2N3OSPurezza:98%Colore e forma:SolidPeso molecolare:311.35HSD17B13-IN-30
CAS:HSD17B13-IN-30 (compound 64) serves as a potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 (HSD17B13), exhibiting an IC 50 value of less than 0.1 μM? with estradiol? as substrates. This compound is significantly implicated in the management of nonalcoholic fatty liver diseases (NAFLDs), including nonalcoholic steatohepatitis (NASH) [1].Formula:C24H16Cl2F3N3O4Colore e forma:SolidPeso molecolare:538.3Etamicastat hydrochloride
CAS:Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.Formula:C14H16ClF2N3OSPurezza:98.54%Colore e forma:SolidPeso molecolare:347.81Ref: TM-T11238L
1mg80,00€5mg173,00€10mg259,00€25mg423,00€50mg577,00€100mg827,00€1mL*10mM (DMSO)190,00€CP-642931
CAS:CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.Formula:C17H25N7OPurezza:99.67% - >99.99%Colore e forma:SolidPeso molecolare:343.43(S)-GNE-140
CAS:(S)-GNE-140 is the less active enantiomer of GNE-140.Formula:C25H23ClN2O3S2Colore e forma:SolidPeso molecolare:499.05GNE-140 racemate
CAS:GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.Formula:C25H23ClN2O3S2Colore e forma:SolidPeso molecolare:499.0411β-HSD1-IN-8
CAS:11β-HSD1-IN-8 is a useful organic compound for research related to life sciences. The catalog number is T65743 and the CAS number is 386704-15-0.Formula:C10H8F3NO3Colore e forma:SolidPeso molecolare:247.173
