Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
AG-120 (racemic)
CAS:AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.Formula:C28H22ClF3N6O3Purezza:99.56%Colore e forma:SolidPeso molecolare:582.96Imidazole-5-propionic acid
CAS:<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Formula:C6H8N2O2Purezza:99.62%Colore e forma:SolidPeso molecolare:140.14Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Formula:C20H18FNO4Purezza:98.33% - 99.58%Colore e forma:SolidPeso molecolare:355.36Fomepizole
CAS:Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.Formula:C4H6N2Purezza:98.1% - 99.94%Colore e forma:Yellow <13°C Solid >13°C LiquidPeso molecolare:82.1PfDHODH-IN-2
CAS:PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.Formula:C13H12ClNO3SPurezza:98.9%Colore e forma:SolidPeso molecolare:297.76Ref: TM-T8767
1mg48,00€5mg97,00€10mg145,00€25mg259,00€50mg383,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)105,00€R162
CAS:R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.Formula:C17H12O3Purezza:96.21% - 98.15%Colore e forma:SolidPeso molecolare:264.28Brequinar sodium
CAS:Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.Formula:C23H14F2NNaO2Purezza:98.16%Colore e forma:SolidPeso molecolare:397.36Ref: TM-T8332
2mg39,00€5mg66,00€10mg97,00€25mg172,00€50mg225,00€100mg314,00€200mg444,00€1mL*10mM (DMSO)78,00€BAY-1436032
CAS:BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).Formula:C26H30F3N3O3Purezza:99.65% - 99.71%Colore e forma:SolidPeso molecolare:489.53Ref: TM-TQ0042
1mg37,00€5mg79,00€10mg119,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)85,00€BI-187004
CAS:BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.Formula:C21H18N4OPurezza:98.63%Colore e forma:SolidPeso molecolare:342.39Nifurtimox
CAS:Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.Formula:C10H13N3O5SPurezza:99.87% - 99.89%Colore e forma:SolidPeso molecolare:287.29WIN 18446
CAS:inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)Formula:C12H20Cl4N2O2Purezza:99.69%Colore e forma:SolidPeso molecolare:366.11VER-246608
CAS:VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.Formula:C28H23ClF2N4O4Purezza:98.5%Colore e forma:SolidPeso molecolare:552.96Ref: TM-T17224
1mg52,00€2mg74,00€5mg111,00€10mg170,00€25mg329,00€50mg502,00€100mg730,00€1mL*10mM (DMSO)137,00€Enasidenib
CAS:Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potentialFormula:C19H17F6N7OPurezza:98% - >99.99%Colore e forma:SolidPeso molecolare:473.38Ref: TM-T2346
5mg47,00€10mg70,00€25mg93,00€50mg111,00€100mg144,00€200mg207,00€500mg350,00€1mL*10mM (DMSO)50,00€DS-1001b
CAS:DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)Formula:C29H29Cl3FN3O4Purezza:99.81%Colore e forma:SolidPeso molecolare:608.92Ref: TM-T7741
1mg37,00€5mg79,00€10mg119,00€25mg187,00€50mg283,00€100mg439,00€200mg635,00€1mL*10mM (DMSO)97,00€G6PDi-1
CAS:G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.Formula:C14H12N4OSPurezza:98.69%Colore e forma:SolidPeso molecolare:284.34BVT-14225
CAS:BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).Formula:C16H20ClN3O3S2Purezza:97.78%Colore e forma:SolidPeso molecolare:401.93Ref: TM-T3542
1mg47,00€2mg59,00€5mg96,00€10mg142,00€25mg254,00€50mg411,00€100mg610,00€1mL*10mM (DMSO)105,00€AZD7545
CAS:AZD7545 is a potent PDHK inhibitor.Formula:C19H18ClF3N2O5SPurezza:99.12% - 99.96%Colore e forma:SolidPeso molecolare:478.87Succinyl phosphonate trisodium salt
CAS:Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)Formula:C4H4Na3O6PPurezza:99.8% - ≥95%Colore e forma:SolidPeso molecolare:248.01BMS-823778 hydrochloride
CAS:<p>BMS-823778 hydrochloride is a potent, selective, and orally active inhibitor of 11β-HSD1 (11β-Hydroxysteroid Dehydrogenase Type 1), demonstrating an IC50 (half</p>Formula:C18H19Cl2N3OColore e forma:SolidPeso molecolare:364.27BVT 2733
CAS:<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formula:C17H21ClN4O3S2Purezza:98% - 99.64%Colore e forma:SolidPeso molecolare:428.96MK-8245
CAS:MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.Formula:C17H16BrFN6O4Purezza:97.58% - 99%Colore e forma:SolidPeso molecolare:467.25Ref: TM-T2650
1mg39,00€5mg96,00€10mg153,00€25mg273,00€50mg465,00€100mg648,00€200mg900,00€1mL*10mM (DMSO)97,00€NCT-501
CAS:NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.Formula:C21H32N6O3Purezza:99.19%Colore e forma:SolidPeso molecolare:416.52LDHA-IN-4
CAS:LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA expressed in E.coli BL21 (DE3) by SPR analysis with an active value of 93 nM.Formula:C25H27N3O6SPurezza:98.17% - 99.68%Colore e forma:SolidPeso molecolare:497.56AGI-5198
CAS:AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).Formula:C27H31FN4O2Purezza:97.37% - 99.23%Colore e forma:SolidPeso molecolare:462.56Galloflavin
CAS:Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.Formula:C12H6O8Purezza:96.24% - 97.47%Colore e forma:SolidPeso molecolare:278.17Ivosidenib
CAS:Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.Formula:C28H22ClF3N6O3Purezza:98.71% - 99.98%Colore e forma:SolidPeso molecolare:582.96Sodium dichloroacetate
CAS:Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.Formula:C2HCl2NaO2Purezza:99.32% - 99.87%Colore e forma:White PowderPeso molecolare:150.92AKR1C3-IN-4
CAS:AKR1C3-IN-4: potent, selective AKR1C3 inhibitor, IC50 = 0.56 μM, potential for CRPC research.Formula:C14H10F3NO2Purezza:98.59%Colore e forma:SolidPeso molecolare:281.23Dihydrouracil
CAS:5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.Formula:C4H6N2O2Purezza:99.75%Colore e forma:SolidPeso molecolare:114.1Nitrofen
CAS:Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.Formula:C12H7Cl2NO3Purezza:99.92%Colore e forma:Less Crystals Or Black Solid Used As A Pre- Or Post-Emergence HerbicidePeso molecolare:284.09NCT-505
CAS:NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 withFormula:C27H28FN5O3SPurezza:99.93%Colore e forma:SolidPeso molecolare:521.61Ref: TM-T12196
1mg115,00€5mg235,00€10mg353,00€25mg562,00€50mg758,00€100mg1.017,00€200mg1.359,00€1mL*10mM (DMSO)270,00€AG-636
CAS:AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.Formula:C21H17N3O2Purezza:99.19%Colore e forma:SolidPeso molecolare:343.38AKR1C3-IN-1
CAS:AKR1C3-IN-1 is a potent and selective inhibitor of AKR1C3(IC50 of 13 nM).Formula:C16H15NO4SPurezza:98.02%Colore e forma:SolidPeso molecolare:317.36L-Allylglycine
CAS:L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.Formula:C5H9NO2Purezza:≥98%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:115.13Carbenoxolone disodium
CAS:Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.Formula:C34H48Na2O7Purezza:99.69%Colore e forma:SolidPeso molecolare:614.72Proguanil hydrochloride
CAS:Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.Formula:C11H17Cl2N5Purezza:98.34% - 98.39%Colore e forma:SolidPeso molecolare:290.19Vidofludimus hemicalcium
CAS:Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formula:C20H18FNO4CaColore e forma:SolidPeso molecolare:375.4PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Formula:C14H11F3N2O2Purezza:99.87%Colore e forma:SolidPeso molecolare:296.24Ref: TM-T12438
1mg50,00€5mg106,00€10mg160,00€25mg311,00€50mg472,00€100mg695,00€200mg938,00€1mL*10mM (DMSO)97,00€PHGDH-inactive
CAS:PHGDH inactive is inactive against PHGDH and serves as a negative control for NCT-502 and NCT-503 [1].Formula:C17H21N5SPurezza:99.83%Colore e forma:SolidPeso molecolare:327.45Ref: TM-T23150
5mg38,00€10mg60,00€25mg117,00€50mg182,00€100mg261,00€200mg366,00€1mL*10mM (DMSO)47,00€NCT-501 hydrochloride
CAS:NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.Formula:C21H33ClN6O3Colore e forma:SolidPeso molecolare:452.98Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Formula:C9H12N2O5SPurezza:99.91%Colore e forma:SolidPeso molecolare:260.27NCT-503
CAS:<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formula:C20H23F3N4SPurezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:408.48CM10
CAS:CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.Formula:C20H23N3OPurezza:99.84%Colore e forma:SolidPeso molecolare:321.42A939572
CAS:A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.Formula:C20H22ClN3O3Purezza:99.96% - ≥95%Colore e forma:SolidPeso molecolare:387.86Ref: TM-T4515
1mg35,00€5mg78,00€10mg115,00€25mg225,00€50mg360,00€100mg567,00€200mg820,00€1mL*10mM (DMSO)81,00€DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purezza:99.13%Colore e forma:SolidPeso molecolare:349.34Ref: TM-T37655
1mg78,00€5mg169,00€10mg250,00€25mg432,00€50mg628,00€100mg905,00€1mL*10mM (DMSO)178,00€Enasidenib mesylate
CAS:Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.Formula:C20H21F6N7O4SPurezza:99.85%Colore e forma:SolidPeso molecolare:569.48GSK1940029
CAS:GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.Formula:C18H16Cl2N4O2Purezza:99.48% - 99.49%Colore e forma:SolidPeso molecolare:391.25Triflupromazine
CAS:Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.Formula:C18H19F3N2SColore e forma:SolidPeso molecolare:352.42Nedosiran
CAS:Nedosiran, a GalNAc-dsRNA conjugate for RNAi, targets LDH to treat primary hyperoxaluria and ESRD.Colore e forma:SolidRef: TM-T39802
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaNitrophenide
CAS:Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.Formula:C12H8N2O4S2Purezza:99.78%Colore e forma:SolidPeso molecolare:308.33
