Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
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hDHODH-IN-2
CAS:hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.Formula:C19H16N2O2Purezza:98%Colore e forma:SolidPeso molecolare:304.349SCH-451659
CAS:SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.Formula:C30H39Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:544.56673-A
CAS:673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.Formula:C15H13NOColore e forma:SolidPeso molecolare:223.27DHODH-IN-12
CAS:DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.Formula:C10H9N3O2Purezza:99.53%Colore e forma:SolidPeso molecolare:203.2Ref: TM-T11021
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg869,00€1mL*10mM (DMSO)129,00€CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Formula:C19H15FN4OSColore e forma:SolidPeso molecolare:366.41Nitrefazole
CAS:Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.Formula:C10H8N4O4Colore e forma:SolidPeso molecolare:248.1911β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Formula:C21H19ClN4OColore e forma:SolidPeso molecolare:378.86MEDS433
CAS:MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.Formula:C20H11F4N3O2Colore e forma:SolidPeso molecolare:401.31hDHODH-IN-11
CAS:hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.Formula:C24H23N3O3Colore e forma:SolidPeso molecolare:401.46RS6212
CAS:<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Formula:C20H22N4O3SColore e forma:SolidPeso molecolare:398.48AMG-221
CAS:AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.Formula:C14H22N2OSPurezza:98%Colore e forma:SolidPeso molecolare:266.411β-HSD1-IN-10
CAS:11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitiveFormula:C16H10F3NO2Colore e forma:SolidPeso molecolare:305.25RORγt/DHODH-IN-2
CAS:RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).Formula:C25H30N4OSColore e forma:SolidPeso molecolare:434.6DHODH-IN-19
CAS:DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)Formula:C22H18ClF6N3O3Colore e forma:SolidPeso molecolare:521.84ASP3662
CAS:ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.Formula:C19H16ClF3N4O2Colore e forma:SolidPeso molecolare:424.8TM-1
CAS:TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.Formula:C26H32N2O6Colore e forma:SolidPeso molecolare:468.54DHODH-IN-3
CAS:DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.Formula:C17H13ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:312.75ALDH3A1-IN-2
CAS:ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.Formula:C11H14N2O3Colore e forma:SolidPeso molecolare:222.2411β-HSD1-IN-9
CAS:<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formula:C13H9F3N2OColore e forma:SolidPeso molecolare:266.22DHODH-IN-21
CAS:DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.Formula:C20H19ClF4N6O4Colore e forma:SolidPeso molecolare:518.85P1788
CAS:P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].Formula:C15H17NO3Colore e forma:SolidPeso molecolare:259.3Epostane
CAS:Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.Formula:C22H31NO3Purezza:>99.99%Colore e forma:SolidPeso molecolare:357.49DHODH-IN-20
CAS:Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.Formula:C24H25F4N3O3Colore e forma:SolidPeso molecolare:479.47ALDH1A1-IN-3
CAS:ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.Formula:C31H36F3N5O4Colore e forma:SolidPeso molecolare:599.64DHODH-IN-24
CAS:DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].Formula:C26H26N4Colore e forma:SolidPeso molecolare:394.51BI-4924
CAS:BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.Formula:C21H20Cl2N2O6SPurezza:99.55%Colore e forma:SolidPeso molecolare:499.36KM04416
CAS:KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.Formula:C12H11NO3SPurezza:99.88%Colore e forma:SolidPeso molecolare:249.29BI-135585
CAS:BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.Formula:C28H32N2O4Purezza:99.45% - 99.57%Colore e forma:SolidPeso molecolare:460.57hDHODH-IN-9
CAS:hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.Formula:C21H21NO4Colore e forma:SolidPeso molecolare:351.4CM026
CAS:CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.Formula:C22H30N6O4Colore e forma:SolidPeso molecolare:442.51ML387
CAS:ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.Formula:C20H21N3O2Purezza:98%Colore e forma:SolidPeso molecolare:335.4Oxycinchophen
CAS:Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.Formula:C16H11NO3Purezza:98%Colore e forma:SolidPeso molecolare:265.26GW648495
CAS:GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.Formula:C16H13N5Purezza:98%Colore e forma:SolidPeso molecolare:275.31BVT-116429
CAS:BVT-116429 is an inhibitor of 11β-HSD1.Formula:C13H12F4N2OSPurezza:98%Colore e forma:SolidPeso molecolare:320.31Genz-669178
CAS:Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).Formula:C17H14N4OSPurezza:98%Colore e forma:SolidPeso molecolare:322.38GA11
CAS:<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Formula:C19H14N2Purezza:98%Colore e forma:SolidPeso molecolare:270.33EN40
CAS:EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).Formula:C13H15NO2Colore e forma:SolidPeso molecolare:217.26p-Valerylphenol
CAS:p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.Formula:C11H14O2Purezza:99.87%Colore e forma:White To Light Beige PowderPeso molecolare:178.23UCK2 Inhibitor-2
CAS:UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.Formula:C28H23N3O4SPurezza:98.76% - 99.25%Colore e forma:SolidPeso molecolare:497.57M77976
CAS:M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.Formula:C17H16N2O3Purezza:99.92%Colore e forma:SolidPeso molecolare:296.32Chlorisondamine diiodide
CAS:Chlorisondamine diiodide is a selective nAChR antagonist and ganglionic blocker that persistently antagonizes partial central effects of nicotine.Formula:C14H20Cl4I2N2Purezza:99.97%Colore e forma:SolidPeso molecolare:611.94INCB13739
CAS:INCB13739 is an 11β-HSD1 inhibitor that can be used in the study of hyperlipidemia and hypertriglyceridemia.Formula:C28H25N3O4Purezza:99.32%Colore e forma:SoildPeso molecolare:467.52Ref: TM-T60203
1mg99,00€5mg226,00€10mg364,00€25mg722,00€50mg998,00€100mg1.320,00€200mg1.795,00€1mL*10mM (DMSO)240,00€IMB-XMA0038
CAS:IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.Formula:C11H10N4O6Purezza:98.94% - 99.96%Colore e forma:SolidPeso molecolare:294.22MDH1-IN-2
CAS:MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.Formula:C25H33NO5Purezza:99.21%Colore e forma:SolidPeso molecolare:427.5311β-HSD1-IN-12
CAS:11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndromeFormula:C19H27ClN2O3SPurezza:99.89%Colore e forma:SolidPeso molecolare:398.95S07-2005 (racemic)
CAS:S07-2005 is a selective AKR1C3 inhibitor with IC50 of 0.13 μM, potential in enhancing cancer chemotherapy.Formula:C20H23NO6Colore e forma:SolidPeso molecolare:373.4AGI-14100
CAS:<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Formula:C29H22ClF4N5O3Purezza:99.91%Colore e forma:SolidPeso molecolare:599.96RV01
CAS:RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.Formula:C17H13NO2Purezza:99.93%Colore e forma:SolidPeso molecolare:263.29Ref: TM-T12781
1mg62,00€5mg135,00€10mg207,00€25mg353,00€50mg509,00€100mg672,00€200mg910,00€1mL*10mM (DMSO)149,00€hDHODH-IN-3
CAS:hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.Formula:C18H19BrN4O2Purezza:99.871%Colore e forma:SolidPeso molecolare:403.27Ref: TM-T11025
1mg64,00€2mg93,00€5mg140,00€10mg215,00€25mg354,00€50mg500,00€100mg658,00€500mgPrezzo su richiesta1mL*10mM (DMSO)150,00€Laflunimus
CAS:Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.Formula:C15H13F3N2O2Purezza:99.86%Colore e forma:SolidPeso molecolare:310.27
