Deidrogenasi
Le deidrogenasi sono enzimi coinvolti nelle reazioni di ossidoriduzione delle vie metaboliche, svolgendo un ruolo centrale nella produzione di energia e nella respirazione cellulare. Questi enzimi sono cruciali per processi come il ciclo dell'acido citrico, la glicolisi e l'ossidazione degli acidi grassi. Gli inibitori delle deidrogenasi sono strumenti importanti nello studio delle malattie metaboliche, del cancro e dello stress ossidativo. Presso CymitQuimica, offriamo una selezione completa di inibitori delle deidrogenasi per supportare la tua ricerca in metabolismo, biologia del cancro e biochimica.
Trovati 302 prodotti di "Deidrogenasi"
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DHODH-IN-13
CAS:<p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>Formula:C10H6F3N3O3Purezza:99.66%Colore e forma:SolidPeso molecolare:273.17DHODH-IN-15
CAS:DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.Formula:C15H11N3O3Purezza:99.8%Colore e forma:SolidPeso molecolare:281.27Ref: TM-T11024
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€200mg1.454,00€1mL*10mM (DMSO)239,00€DHODH-IN-1
CAS:<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formula:C21H20F3N3O2Purezza:99.76%Colore e forma:SolidPeso molecolare:403.4DHODH-IN-17
CAS:DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.Formula:C12H9ClN2O2Purezza:99.52% - 99.99%Colore e forma:SolidPeso molecolare:248.67Ref: TM-T60364
5mg46,00€10mg69,00€25mg126,00€50mg182,00€100mg269,00€200mg376,00€1mL*10mM (DMSO)48,00€DHODH-IN-4
CAS:DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.Formula:C17H12Cl2N2O2Purezza:99.34%Colore e forma:SolidPeso molecolare:347.2Ref: TM-T11027
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)261,00€DHODH-IN-8
CAS:DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).Formula:C17H13ClN2O2Purezza:99.78%Colore e forma:SolidPeso molecolare:312.75Ref: TM-T11030
1mg115,00€2mg172,00€5mg255,00€10mg374,00€25mg562,00€50mg787,00€100mg1.074,00€500mgPrezzo su richiesta1mL*10mM (DMSO)249,00€BRD9185
CAS:BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.Formula:C23H21F6N3O2Purezza:98%Colore e forma:SolidPeso molecolare:485.42ML-148
CAS:ML-148 is a selective inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH, IC50 = 56 nM).Formula:C20H21N3OPurezza:99.88%Colore e forma:SolidPeso molecolare:319.4Ref: TM-T38163
1mg60,00€5mg165,00€10mg254,00€25mg459,00€50mg658,00€100mg935,00€200mg1.283,00€1mL*10mM (DMSO)188,00€hDHODH-IN-5
CAS:hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).Formula:C21H21F3N2O2Purezza:99.55%Colore e forma:SolidPeso molecolare:390.4Ref: TM-T11029
1mg85,00€5mg166,00€10mg234,00€25mg376,00€50mg560,00€100mg797,00€1mL*10mM (DMSO)175,00€11β-HSD1-IN-1
CAS:11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.Formula:C18H14ClF4N3OPurezza:99.84%Colore e forma:SolidPeso molecolare:399.77Ref: TM-T10160
1mg52,00€5mg111,00€10mg163,00€25mg235,00€50mg330,00€100mg452,00€1mL*10mM (DMSO)118,00€hDHODH-IN-4
CAS:hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.Formula:C21H24N4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:364.44AZD8329
CAS:AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.Formula:C25H31N3O3Purezza:99.31%Colore e forma:SolidPeso molecolare:421.53Ref: TM-T14383
1mg92,00€5mg188,00€10mg311,00€25mg645,00€50mg947,00€100mg1.644,00€1mL*10mM (DMSO)215,00€ALDH1A1-IN-2
CAS:ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesityFormula:C25H23ClN4O3SPurezza:99.48%Colore e forma:SolidPeso molecolare:494.99Manitimus
CAS:Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.Formula:C15H11F3N2O2Purezza:99.75% - 99.75%Colore e forma:SolidPeso molecolare:308.26NCT-506
CAS:NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).Formula:C25H23FN4O3SPurezza:98%Colore e forma:SolidPeso molecolare:478.54Metapramine
CAS:Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.Formula:C16H18N2Purezza:99.03% - 99.67%Colore e forma:SolidPeso molecolare:238.33DS18561882
CAS:DS18561882: Potent MTHFD2 inhibitor (IC50=0.0063), inhibits MTHFD1 (IC50=0.57), good oral kinetics.Formula:C28H31F3N4O6SPurezza:98.19% - >99.99%Colore e forma:SolidPeso molecolare:608.63Ref: TM-T11103
1mg115,00€5mg274,00€10mg432,00€25mg777,00€50mg1.264,00€100mg1.700,00€1mL*10mM (DMSO)378,00€PBRM
CAS:PBRM (17β-HSD1-IN-2) is a selective covalent inhibitor of 17β-HSD1, used in breast cancer and endometriosis research.Formula:C28H34BrNO2Purezza:99.56% - 99.59%Colore e forma:SolidPeso molecolare:496.48CPS-11
CAS:CPS-11, a Thalidomide analogue, shows potent, broad antitumor activity, especially in multiple myeloma cells.Formula:C14H12N2O5Purezza:99.8% - 99.98%Colore e forma:SolidPeso molecolare:288.26IDH2R140Q-IN-2
CAS:IDH2R140Q-IN-2 is an IDH2R140Q inhibitor indicated for the study of acute myeloid leukaemia (AML).Formula:C21H18F6N6OPurezza:99.92%Colore e forma:SolidPeso molecolare:484.4ALDH1A3-IN-2
CAS:ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.Formula:C13H17NOPurezza:99.84%Colore e forma:SolidPeso molecolare:203.28BMS-823778
CAS:<p>BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.</p>Formula:C18H18ClN3OPurezza:99.39% - 99.75%Colore e forma:SolidPeso molecolare:327.81Ref: TM-T71394
1mg167,00€2mg246,00€5mg411,00€10mg562,00€25mg867,00€50mg1.121,00€100mg1.425,00€200mg1.882,00€HSD-016
CAS:HSD-016: Oral 11β-HSD1 inhibitor, active in humans, mice, rats (IC50: 11, 1, 8 nM), potential for type 2 diabetes research.Formula:C21H21F7N2O3SPurezza:99.40% - >99.99%Colore e forma:SolidPeso molecolare:514.46Ref: TM-T63569
1mg88,00€5mg296,00€10mg464,00€25mg938,00€50mg1.568,00€100mg2.490,00€1mL*10mM (DMSO)328,00€Qc1
CAS:Qc1 is an inhibitor of threonine dehydrogenase (TDH) inhibitor and can be used in studies about metabolic diseases.Formula:C23H16F3N3O2SPurezza:99.75%Colore e forma:SolidPeso molecolare:455.45G6PD activator AG1
CAS:G6PD activator AG1 is a G6PD agonist that promotes G6PD oligomerization to a catalytically competent form.Formula:C24H30N4S2Purezza:98.38% - 99.51%Colore e forma:SolidPeso molecolare:438.65Olorofim
CAS:Olorofim（F-901318）is a new selective antifungal compound that inhibits Aspergillus fumigatus DHODH (IC50: 44 nM). Cost-effective and quality-assured.Formula:C28H27FN6O2Purezza:99.28%Colore e forma:SolidPeso molecolare:498.55IGP-1
CAS:iGP-1 is a cell-permeable mitochondrial sn-Glycerol 3-phosphate dehydrogenase (mGPDH) inhibitor.Formula:C17H15N3O3Purezza:99.12% - 99.15%Colore e forma:SolidPeso molecolare:309.32Ref: TM-T25526
2mg35,00€5mg52,00€10mg74,00€25mg133,00€50mg202,00€100mg321,00€200mg469,00€1mL*10mM (DMSO)88,00€CM037
CAS:CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminateFormula:C21H25N3O3S2Purezza:99.77%Colore e forma:SolidPeso molecolare:431.57DSM421
CAS:DSM421 (DSM-421) is a dihydrodehydrogenase inhibitor (DHODH) that is in preclinical development as a potential treatment option for malaria and has shownFormula:C14H11F5N6Purezza:99.67% - 99.82%Colore e forma:SolidPeso molecolare:358.27Ref: TM-T27214
1mg116,00€5mg273,00€10mg373,00€25mg563,00€50mg758,00€100mg998,00€200mg1.320,00€1mL*10mM (DMSO)319,00€IMPDH2-IN-2
CAS:IMPDH2-IN-2 is an IMPDH inhibitor with antimicrobial activity and potential anti-tuberculosis activity for the study of inflammation and immune dysfunction.Formula:C21H15Cl2N3O3Purezza:99.02%Colore e forma:SolidPeso molecolare:428.27PHGDH-IN-3
CAS:PHGDH-IN-3, an oral PHGDH blocker with 2.8 μM IC50, may help in cancer research.Formula:C24H18FN3O4S2Purezza:97.24% - 99.1%Colore e forma:SolidPeso molecolare:495.55PKUMDL-WQ-2101
CAS:PKUMDL-WQ-2101 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase with anti-tumor activity.Formula:C14H11N3O6Purezza:99.57%Colore e forma:SolidPeso molecolare:317.25hDHODH-IN-7
CAS:hDHODH-IN-7 (DHODH-IN-9) is a nitrogen-containing analog and is a human dihydrorotatory dehydrogenase inhibitor.Formula:C21H23FN4OPurezza:99.87%Colore e forma:SolidPeso molecolare:366.43Ref: TM-T11031
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mg2.147,00€1mL*10mM (DMSO)266,00€15-PGDH-IN-2
CAS:15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].Formula:C16H13NO3S2Colore e forma:SolidPeso molecolare:331.41Tetrahydro-11-dehydrocorticosterone
CAS:Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].Formula:C21H32O4Colore e forma:SolidPeso molecolare:348.48AKR1C3-IN-6
CAS:AKR1C3-IN-6: Strong AKR1C3 inhibitor (IC50: 0.31 μM); weak on AKR1C2 (IC50: 73.23 μM); shows antitumor effects.Formula:C18H15F3N4O3Colore e forma:SolidPeso molecolare:392.33Anticancer agent 121
CAS:Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].Formula:C19H18N2O3SColore e forma:SolidPeso molecolare:354.42YG1702
CAS:YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.Formula:C23H30N2O7SColore e forma:SolidPeso molecolare:478.56MK-0736 hydrochloride
CAS:MK-0736 hydrochloride is a potent and selective 11β-HSD-1 inhibitor.Formula:C23H31ClF3N3O2SColore e forma:SolidPeso molecolare:506.03DHODH-IN-22
CAS:DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.Formula:C21H21ClF4N6O5Colore e forma:SolidPeso molecolare:548.88CHK-336
CAS:CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluriaFormula:C24H20F2N4O4S2Colore e forma:SolidPeso molecolare:530.57MK-0736
CAS:MK-0736 is a potent and selective 11β-HSD-1 inhibitor.Formula:C23H30F3N3O2SColore e forma:SolidPeso molecolare:469.56PF-915275
CAS:PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.Formula:C18H14N4O2SPurezza:99.58% - 99.61%Colore e forma:SolidPeso molecolare:350.39Ref: TM-T16510
1mg38,00€2mg49,00€5mg81,00€10mg127,00€25mg255,00€50mg499,00€100mg723,00€500mg1.510,00€1mL*10mM (DMSO)89,00€DHODH-IN-14
CAS:DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.Formula:C15H7F4N3O3Purezza:99.81%Colore e forma:SolidPeso molecolare:353.23Ref: TM-T11023
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg792,00€100mg1.064,00€500mgPrezzo su richiesta1mL*10mM (DMSO)264,00€S07-1066
CAS:S07-1066, an aldo-keto reductase 1C3 (AKR1C3) inhibitor, enhances doxorubicin (DOX) cytotoxicity by selectively inhibiting AKR1C3-mediated reduction of DOX andFormula:C16H11Cl2FO2Purezza:98%Colore e forma:SolidPeso molecolare:325.16hDHODH-IN-1
CAS:hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.Formula:C17H14N2O2Purezza:99.97%Colore e forma:SolidPeso molecolare:278.31Ref: TM-T11546
1mg35,00€5mg74,00€10mg109,00€25mg210,00€50mg306,00€100mg426,00€200mg575,00€1mL*10mM (DMSO)82,00€IDH889
CAS:IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).Formula:C23H25FN6O2Purezza:≥98%Colore e forma:SolidPeso molecolare:436.4811α-Hydroxyprogesterone
CAS:11alpha-Hydroxyprogesterone, an inactive analogue of 11beta-Hydroxyprogesterone, serves as an experimental control. Meanwhile, 11beta-Hydroxyprogesterone functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase and activates the human mineralocorticoid receptor in COS-7 cells, with an effective dose (ED)50 of 10 nM.Formula:C21H30O3Colore e forma:SolidPeso molecolare:330.468HSD17B13-IN-2
CAS:HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1Formula:C21H23F2NO4Colore e forma:SolidPeso molecolare:391.41IDH1 Inhibitor 2
CAS:IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).Formula:C26H22N4OPurezza:98%Colore e forma:SolidPeso molecolare:406.48
