AhR
Il recettore degli idrocarburi arilici (AhR) è un fattore di trascrizione attivato da ligandi che svolge un ruolo cruciale nella regolazione delle risposte biologiche ai contaminanti ambientali, come le diossine. AhR è coinvolto anche nel metabolismo degli xenobiotici e nella regolazione delle risposte immunitarie, della proliferazione e differenziazione cellulare. La disregolazione della segnalazione AhR è associata a diverse malattie, tra cui il cancro e i disturbi autoimmuni. Presso CymitQuimica, offriamo una gamma di inibitori di AhR per supportare la tua ricerca in tossicologia, biologia del cancro e immunologia.
Trovati 41 prodotti di "AhR"
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Leflunomide
CAS:Leflunomide (HWA486) is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.Formula:C12H9F3N2O2Purezza:99.52% - 99.96%Colore e forma:Off White Crystalline SolidPeso molecolare:270.21Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Formula:C11H18ClNOPurezza:99.88%Colore e forma:White To Off-White SolidPeso molecolare:215.72BAY 2416964
CAS:BAY 2416964 is a small molecule inhibitor that selectively targets aromatic receptor (AhR) and is commonly used in tumor research. Cost-effective and quality-assured.Formula:C18H18ClN5O3Purezza:99.15% - 99.85%Colore e forma:SolidPeso molecolare:387.82GNF351
CAS:GNF351: Full AHR antagonist, inhibits DRE-dependent/independent activity, low toxicity, binds AHR (IC50: 62 nM).Formula:C24H25N7Purezza:98.43%Colore e forma:SolidPeso molecolare:411.5Diosmin
CAS:Diosmin (Venosmine) is a bioflavonoid that strengthens vascular walls.Formula:C28H32O15Purezza:97.90%Colore e forma:Greyish-Yellow Or Light Yellow Hygroscopic PowderPeso molecolare:608.54MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Formula:C17H12BrN3O2Purezza:99.64%Colore e forma:SolidPeso molecolare:370.2WAY-605471
CAS:WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.Formula:C14H15NO3S2Purezza:99.62%Colore e forma:SolidPeso molecolare:309.4KYN-101
CAS:<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formula:C22H19FN6Purezza:98.35%Colore e forma:SolidPeso molecolare:386.43AHR Inhibitor I-103
CAS:AHR Inhibitor I-103 is an aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity used in the study of breast cancer and acute myeloid leukemia.Formula:C21H17FN6Purezza:98.70%Colore e forma:SoildPeso molecolare:372.43',4'-Dimethoxyflavone
CAS:3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.Formula:C17H14O4Purezza:98.05%Colore e forma:SolidPeso molecolare:282.29StemRegenin 1 Hydrochloride
CAS:StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.Formula:C24H24ClN5OSPurezza:99.94%Colore e forma:SolidPeso molecolare:466Carbidopa monohydrate
CAS:<p>Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.</p>Formula:C10H16N2O5Purezza:98.11% - 98.30%Colore e forma:SolidPeso molecolare:244.24PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purezza:98.63% - >99.99%Colore e forma:Yellow SolidPeso molecolare:267.28Indole-3-pyruvic acid
CAS:Indole-3-pyruvic acid is a precursor for the plant growth hormone indole-3-acetic acid.Formula:C11H9NO3Purezza:98.89% - 99.21%Colore e forma:Off White CrystalsPeso molecolare:203.19VAF347
CAS:VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects.Formula:C17H11ClF3N3Purezza:98.75% - 99.55%Colore e forma:SolidPeso molecolare:349.745-fluoro 203
CAS:5-fluoro 203 (NSC-703786) is a cytotoxic molecule leading to cell death by forming DNA adducts.Formula:C14H11FN2SPurezza:97.61%Colore e forma:SolidPeso molecolare:258.31Indole-3-carbinol
CAS:Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinaseFormula:C9H9NOPurezza:98.59% - >99.99%Colore e forma:SolidPeso molecolare:147.17Benzyl butyl phthalate
CAS:<p>Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.</p>Formula:C19H20O4Purezza:99.02%Colore e forma:Colourless Liquid Oily LiquidPeso molecolare:312.36FICZ
CAS:FICZ (6-Formylindolo[3,2-b]carbazole) is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).Formula:C19H12N2OPurezza:98.97%Colore e forma:SolidPeso molecolare:284.31CH-223191
CAS:CH-223191, a specific aryl hydrocarbon receptor (AhR) antagonist, inhibited TCDD-induced luciferase activity with an IC50 of 0.03 μM. High-Quality, Low-Cost!Formula:C19H19N5OPurezza:99.01% - 99.71%Colore e forma:SolidPeso molecolare:333.39L-Kynurenine
CAS:L-Kynurenine ((S)-Kynurenine)) is an endogenous agonist of aryl hydrocarbon receptor (AHR) ,inhibits allogeneic T cell proliferation. High-Quality, Low-Cost!Formula:C10H12N2O3Purezza:98.44% - 99.91%Colore e forma:Light Yellow CrystallinePeso molecolare:208.21BAY-218
CAS:Bindarit (AF2838) is an aryl hydrocarbon receptor (AHR) antagonist.Cost-effective and quality-assured.Formula:C20H17ClFN3O3Purezza:99.46% - 99.85%Colore e forma:SolidPeso molecolare:401.82Carbidopa
CAS:<p>Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM).</p>Formula:C10H14N2O4Purezza:98.01% - ≥98%Colore e forma:SolidPeso molecolare:226.23Tapinarof
CAS:Tapinarof (Benvitimod) is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.Formula:C17H18O2Purezza:99.64% - >99.99%Colore e forma:SolidPeso molecolare:254.32PDM11
CAS:PDM11 (1-[2-(4-Chloro-phenyl)-vinyl]-3,5-diMeth) is an antagonist of aryl hydrocarbon receptor (AhR)Formula:C16H15ClO2Purezza:99.88%Colore e forma:SolidPeso molecolare:274.74ITE
CAS:ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), has immunosuppressive activity.Formula:C14H10N2O3SPurezza:97.91% - 99.14%Colore e forma:SolidPeso molecolare:286.31CAY 10465
CAS:CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).Formula:C15H9Cl2F3Purezza:98.80%Colore e forma:SolidPeso molecolare:317.13StemRegenin 1
CAS:StemRegenin 1 (SR1) is an aryl hydrocarbon receptor (AhR) inhibitor.Formula:C24H23N5OSPurezza:98% - 99.89%Colore e forma:SolidPeso molecolare:429.54PDM2
CAS:PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.Formula:C14H9Cl3Purezza:99.44%Colore e forma:SolidPeso molecolare:283.58Skatole
CAS:Skatole (3-Methyl-1H-indole), produced by bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.Formula:C9H9NPurezza:99.74%Colore e forma:Leaves From Petroleum Ether; White-Brown Scales SolidPeso molecolare:131.17Brevifolincarboxylic acid
CAS:Natural α-glucosidase inhibitor from Polygonum capitatum; blocks AhR with 323.46 μM IC50.Formula:C13H8O8Purezza:99.42% - 99.59%Colore e forma:SolidPeso molecolare:292.201,4-Chrysenequinone
CAS:<p>1,4-Chrysenequinone (Chrysene-1,4-dione) is an activator of aryl hydrocarbon receptor (AhR).</p>Formula:C18H10O2Purezza:99.07% - 99.84%Colore e forma:SolidPeso molecolare:258.27Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurezza:97.71% - >99.99%Colore e forma:SolidPeso molecolare:367.3YL-109
CAS:<p>YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro and in vivo.</p>Formula:C14H11NO2SPurezza:99.77% - ≥95%Colore e forma:SolidPeso molecolare:257.31DiMNF
CAS:Imigliptin (KBP 3853) is a dipeptidyl peptidase-4 inhibitor used in the study of type 2 diabetes.Formula:C21H16O4Purezza:97.60%Colore e forma:SolidPeso molecolare:332.35L-Kynurenine-d4
CAS:L-Kynurenine-d4 is a deuterated isotope compound of L-Kynurenine. L-Kynurenine is a metabolite of tryptophan and an endogenous agonist of the AHR.Formula:C10H8D4N2O3Colore e forma:SolidPeso molecolare:212.24D-Kynurenine
CAS:<p>D-Kynurenine, ZINC901103, metabolizes from D-tryptophan, activates AhR, changes epithelium to mesenchyme, and tests for D-amino acid oxidase.</p>Formula:C10H12N2O3Purezza:99.68%Colore e forma:SolidPeso molecolare:208.21Phortress
CAS:<p>Phortress (NSC-710305) is a potent AhR ligand with strong binding affinity, which subsequently triggers the transcription of CYP1A1 and induces antitumor</p>Formula:C20H25Cl2FN4OSPurezza:99.89%Colore e forma:SolidPeso molecolare:459.41Prochloraz
CAS:Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.Formula:C15H16Cl3N3O2Purezza:99.75% - 99.79%Colore e forma:Colorless SolidPeso molecolare:376.67CAY10464
CAS:CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.Formula:C15H12Cl2OPurezza:99.96%Colore e forma:SolidPeso molecolare:279.16AhR agonist 2
<p>AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.</p>Formula:C12H7Br2N3Colore e forma:SolidPeso molecolare:353.01
