Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 133 prodotti di "Lipossigenasi"
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L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formula:C22H14F3NO2S2Colore e forma:SolidPeso molecolare:445.48BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColore e forma:SolidPeso molecolare:330.4AHR-5333
CAS:<p>AHR-5333 an antiallergy agent.</p>Formula:C30H33F2NO4Purezza:98%Colore e forma:SolidPeso molecolare:509.58S-2474
CAS:<p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>Formula:C20H31NO3SPurezza:99.03%Colore e forma:SolidPeso molecolare:365.53Utreloxastat
CAS:<p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>Formula:C18H28O2Purezza:99.95%Colore e forma:SolidPeso molecolare:276.415-LOX-IN-1
CAS:<p>5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.</p>Formula:C20H18N2O2SPurezza:97.45%Colore e forma:SolidPeso molecolare:350.43Butibufen
CAS:Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.Formula:C14H20O2Purezza:98.11% - 98.91%Colore e forma:SolidPeso molecolare:220.31A-69412
CAS:A-69412 is a reversible 5-lipoxygenase inhibitor, potentially treating ulcerative colitis and asthma.Formula:C7H10N2O3Purezza:99.54%Colore e forma:SolidPeso molecolare:170.17Lonapalene
CAS:<p>Lonapalene is a topically effective inhibitor of 5-lipoxygenase.</p>Formula:C16H15ClO6Purezza:98.67% - 99.33%Colore e forma:SolidPeso molecolare:338.74h15-LOX-2 inhibitor 1
CAS:<p>Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].</p>Formula:C17H13F3N2SPurezza:98%Colore e forma:SolidPeso molecolare:334.36A 79175
CAS:A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.Formula:C15H13FN2O4Purezza:98%Colore e forma:SolidPeso molecolare:304.27AA 863
CAS:AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.Formula:C21H26O5Purezza:98%Colore e forma:SolidPeso molecolare:358.43L 670630
CAS:<p>L 670630 is a potent and orally active 5-lipoxygenase inhibitor.</p>Formula:C25H26O3Purezza:98%Colore e forma:SolidPeso molecolare:374.47Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Formula:C16H12ClNO3Purezza:98.87%Colore e forma:SolidPeso molecolare:301.72MLS000545091
CAS:MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.Formula:C14H15ClN2OPurezza:99.84%Colore e forma:SolidPeso molecolare:262.73(2E,9Z)-Octadeca-2,9-dienoic acid
CAS:(2E,9Z)-Octadeca-2,9-dienoic acid, a polyunsaturated fatty acid, is utilized in the study of lipoxygenase-dependent metabolism [1].Formula:C18H32O2Colore e forma:SolidPeso molecolare:280.45TA-270
CAS:TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.Formula:C29H36N2O7Colore e forma:SolidPeso molecolare:524.6117(S)-HpDHA
CAS:17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].Formula:C22H32O4Colore e forma:SolidPeso molecolare:360.495-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Formula:C23H28N4O2SColore e forma:SolidPeso molecolare:424.56CMI-392
CAS:CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).Formula:C31H37ClN2O8SPurezza:98%Colore e forma:SolidPeso molecolare:633.155,6-dehydro Arachidonic Acid
CAS:5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.Formula:C20H30O2Colore e forma:SolidPeso molecolare:302.45A 78773
CAS:A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.Formula:C15H13FN2O4Colore e forma:SolidPeso molecolare:304.27CCT365623
CAS:<p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>Formula:C18H17NO4S3Purezza:97.299% - 99.49%Colore e forma:SolidPeso molecolare:407.53PXS-6302 hydrochloride
CAS:<p>PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3</p>Formula:C10H11ClF3NO2SPurezza:99.89%Colore e forma:SoildPeso molecolare:301.71Setileuton
CAS:<p>Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.</p>Formula:C22H17F4N3O4Purezza:98.85% - 99.35%Colore e forma:SolidPeso molecolare:463.38ALOX15-IN-1
ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.Formula:C24H31N3O5SColore e forma:SolidPeso molecolare:473.59L 691816
CAS:L 691816 is an effective inhibitor of the 5-LO reaction.Formula:C36H35ClN6OSPurezza:98%Colore e forma:SolidPeso molecolare:635.22h15-LOX-2 inhibitor 3
CAS:<p>Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.</p>Formula:C22H13N5O3Colore e forma:SolidPeso molecolare:395.375-LOX/MAOs-IN-1
CAS:<p>Compound 3, known as 5-LOX/MAOs-IN-1, acts as an inhibitor of 5-LOX/MAOs and is an effective free radical scavenger, displaying antioxidant characteristics. It has demonstrated neuroprotective effects in cell models damaged by oxidative stress and is capable of activating the neurogenesis microenvironment in adult mouse neural stem cells. This compound is utilized in research focused on neurodegenerative diseases.</p>Formula:C18H18N2O2Colore e forma:SolidPeso molecolare:294.35AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Formula:C19H21NO3S2Purezza:98%Colore e forma:SolidPeso molecolare:375.5Resolvin E2
CAS:RvE2, a bioactive lipid from the SPM family, is made from EPA and reduces inflammatory neutrophil infiltration and helps treat NAFLD and other diseases.Formula:C20H30O4Colore e forma:SolidPeso molecolare:334.45ALOX15-IN-2
CAS:ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.Formula:C23H29N3O4SPurezza:99.98%Colore e forma:SolidPeso molecolare:443.56CJ-13,610
CAS:CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages.Formula:C22H23N3O2SPurezza:99.64%Colore e forma:SolidPeso molecolare:393.5
