Lipossigenasi
Le lipossigenasi sono una famiglia di enzimi che catalizzano l'ossigenazione degli acidi grassi polinsaturi, portando alla produzione di mediatori lipidici bioattivi come i leucotrieni e le lipossine. Questi mediatori svolgono ruoli critici nell'infiammazione, nelle risposte immunitarie e nel cancro. Gli inibitori della lipossigenasi sono utilizzati per studiare il loro ruolo nelle malattie infiammatorie, nell'asma e nel cancro. Presso CymitQuimica, offriamo una varietà di inibitori della lipossigenasi per supportare la tua ricerca in infiammazione, oncologia e metabolismo lipidico.
Trovati 134 prodotti di "Lipossigenasi"
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4-MMPB
CAS:15-Lipoxygenase Inhibitor 1 is a selective inhibitor of 15-lipoxygenase, with an IC50 of 18 μM.Formula:C16H19N5SPurezza:97.18%Colore e forma:SolidPeso molecolare:313.42Ref: TM-T8794
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg86,00€25mg156,00€50mg245,00€100mg403,00€200mg568,00€Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3Ref: TM-T3S0153
50mgPrezzo su richiesta1mg49,00€5mg92,00€1mL*10mM (DMSO)113,00€10mg166,00€25mg268,00€LOX-IN-3 dihydrochloride
CAS:LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX).Formula:C13H15Cl2FN2O2SPurezza:99.95% - 99.96%Colore e forma:SolidPeso molecolare:353.24Ref: TM-T39986
1mg54,00€5mg114,00€1mL*10mM (DMSO)120,00€10mg178,00€25mg334,00€50mg557,00€100mg888,00€200mg1.251,00€Terameprocol
CAS:Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.Formula:C22H30O4Purezza:99.38%Colore e forma:SolidPeso molecolare:358.47Phenethyl ferulate
CAS:Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).Formula:C18H18O4Purezza:99.88% - 99.91%Colore e forma:SolidPeso molecolare:298.33Ref: TM-TN2330
1mg56,00€1mL*10mM (DMSO)114,00€5mg119,00€10mg192,00€25mg323,00€50mg475,00€100mg687,00€Phenidone
CAS:Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.Formula:C9H10N2OPurezza:97.24%Colore e forma:White Solid Solid CrystallinePeso molecolare:162.19Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Formula:C16H11N3O2Purezza:99.55%Colore e forma:Dark Red SolidPeso molecolare:277.28Chebulagic acid
CAS:Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.Formula:C41H30O27Purezza:97.82% - 99.8%Colore e forma:SolidPeso molecolare:954.66Ref: TM-TQ0180
1mg74,00€5mg157,00€10mg225,00€1mL*10mM (DMSO)244,00€25mg376,00€50mg560,00€100mg798,00€11-Keto-β-boswellic acid
CAS:11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor, exerts dose dependent cardioprotective effect manifested.Formula:C30H46O4Purezza:99.68%Colore e forma:SolidPeso molecolare:470.68Ref: TM-TN1182
1mg57,00€5mg130,00€1mL*10mM (DMSO)133,00€10mg200,00€25mg338,00€50mg497,00€100mg710,00€ML355
CAS:ML355, a specific, effective 12-Lipoxygenase(12-LOX) inhibitors(IC50=0.34 μM), possess favorable ADME properties.
Formula:C21H19N3O4S2Purezza:98.02% - 98.2%Colore e forma:SolidPeso molecolare:441.523-Hydroxycoumarin
CAS:3-Hydroxycoumarin is a natural compound, and is human 15-LOX-1 inhibitorsFormula:C9H6O3Purezza:99.5% - 99.77%Colore e forma:SolidPeso molecolare:162.14Licofelone
CAS:Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.Formula:C23H22ClNO2Purezza:99.25%Colore e forma:Yellowish SolidPeso molecolare:379.88Ref: TM-T6568
5mg44,00€1mL*10mM (DMSO)48,00€10mg66,00€25mg119,00€50mg177,00€100mg264,00€200mg394,00€500mg623,00€3-O-Acetyl-11-hydroxy-β-boswellic acid
CAS:3-O-Acetyl-11-hydroxy-beta-boswellic acid is the precursor of 3-O-acetyl-9, 11-dehydro-beta-boswellic acid(a 5-lipoxygenase inhibitor ).Formula:C32H50O5Purezza:98.24%Colore e forma:SolidPeso molecolare:514.74Linoleyl alcohol
CAS:Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1].Formula:C18H34OPurezza:98.12%Colore e forma:SolidPeso molecolare:266.46Nordihydroguaiaretic acid
CAS:Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFormula:C30H48O3Purezza:99.2% - 99.96%Colore e forma:Off-White SolidPeso molecolare:456.70Ref: TM-TN1097
1mg58,00€5mg137,00€1mL*10mM (DMSO)161,00€10mg212,00€25mg363,00€50mg527,00€100mg747,00€ML351
CAS:ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).Formula:C15H11N3OPurezza:97.67%Colore e forma:SolidPeso molecolare:249.27Ref: TM-T21902
1mg50,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg167,00€25mg334,00€50mg505,00€100mg713,00€FPL 62064
CAS:FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandinFormula:C16H15N3OPurezza:98.79%Colore e forma:SolidPeso molecolare:265.31Ref: TM-T8356
2mg35,00€5mg52,00€1mL*10mM (DMSO)73,00€10mg86,00€25mg136,00€50mg198,00€100mg298,00€200mg414,00€PGS-IN-1
CAS:PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).Formula:C19H26O3Purezza:99.39%Colore e forma:SolidPeso molecolare:302.41a-Boswellic Acid
CAS:Prodotto controllatoApplications The principal constitutents of frankincense (olibanum). A specific, nonredox inhibitor of 5-lipoxygenase used to treat inflammation.
References Safayhi, H. et al.: J. Pharmacol. Exp. Therap., 261, 1143 (1992); Siemoneit, U., et al.: Eur. J. Pharmacol., 606, 246 (2009); Cao, H. et al.: Pharamacol. Res., 61, 519 (2010);Formula:C30H48O3Colore e forma:NeatPeso molecolare:456.7Golocdacimab
CAS:Golocdacimab (anti-LOX-1 mAb) targets LOX-1, with potential applications for type 2 diabetes complications and preventing HAE attacks.Purezza:95%Colore e forma:LiquidPeso molecolare:~150 kDa4-(2-Methylpropyl)benzenemethanol
CAS:Prodotto controllatoFormula:C11H16OColore e forma:NeatPeso molecolare:164.24Atreleuton
CAS:Atreleuton (ABT-761), reversible oral 5-LO inhibitor, selectively blocks leukotriene formation.Formula:C16H15FN2O2SPurezza:98%Colore e forma:SolidPeso molecolare:318.37L 656224
CAS:L 656224 is a 5-LO inhibitor.Formula:C20H21ClO3Purezza:98%Colore e forma:SolidPeso molecolare:344.83Fenleuton
CAS:Fenleuton is a 5-lipoxygenase inhibitor.Formula:C17H15FN2O3Purezza:98%Colore e forma:SolidPeso molecolare:314.31LP117
CAS:LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).Formula:C21H23ClN4O2SPurezza:98%Colore e forma:SolidPeso molecolare:430.95YS-121
CAS:YS121 inhibits mPGES-1 (IC50=3.4μM) & 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).Formula:C20H26ClN3O2SColore e forma:SolidPeso molecolare:407.96LY 221068
CAS:LY 221068 is a potent antioxidant with anti-inflammatory activity.Formula:C20H30N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:362.53AHR-5333
CAS:AHR-5333 an antiallergy agent.Formula:C30H33F2NO4Purezza:98%Colore e forma:SolidPeso molecolare:509.58LY 269415
CAS:LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.Formula:C19H28N2O2SColore e forma:SolidPeso molecolare:348.5Lipoxygenin
CAS:Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.Formula:C24H22N2O4Colore e forma:SolidPeso molecolare:402.44Cgp 8065
CAS:Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.Formula:C16H15N3O4S2Colore e forma:SolidPeso molecolare:377.44HZ52
CAS:HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.Formula:C24H26ClN3O2SColore e forma:SolidPeso molecolare:456EP6
CAS:EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.Formula:C24H30N4OPurezza:98%Colore e forma:SolidPeso molecolare:390.52RG 6866
CAS:RG 6866 is a inhibitor of 5-lipoxygenase.Formula:C16H17NO3Purezza:98%Colore e forma:SolidPeso molecolare:271.31ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Formula:C24H23NO2SPurezza:98%Colore e forma:SolidPeso molecolare:389.51Fluindione
CAS:Fluindione is a hematologic drug.Formula:C15H9FO2Colore e forma:SolidPeso molecolare:240.23BI-L 357
CAS:BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.Formula:C18H18O4SColore e forma:SolidPeso molecolare:330.42-TEDC
CAS:2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.Formula:C16H13NO4SPurezza:99.97%Colore e forma:SolidPeso molecolare:315.34Texasin
CAS:Texasin is a selective inhibitor of human leukocyte 5-lipoxygenase.Formula:C16H12O5Purezza:98%Colore e forma:SolidPeso molecolare:284.26L-651392
CAS:L-651392 is an inhibitor of leukotriene.Formula:C14H10BrNO3SColore e forma:SolidPeso molecolare:352.2MLS000536924
CAS:MLS000536924 is a potent and selective competitive human epithelial 15-lipoxygenase-2 inhibitor.Formula:C16H15N3SColore e forma:SolidPeso molecolare:281.38tHGA
CAS:tHGA is a potent inhibitor of lipoxygenase.Formula:C18H24O4Purezza:98%Colore e forma:SolidPeso molecolare:304.38L 652343
CAS:L 652343 is an inhibitor of cyclooxygenase and 5-lipoxygenase in vitro. It also inhibits the synthesis of the products of both these pathways in whole cells.Formula:C22H14F3NO2S2Colore e forma:SolidPeso molecolare:445.48SB 210661
CAS:SB 210661 is a potent and selective 5-lipoxygenase inhibitor.Formula:C16H14F2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:336.29Enazadrem
CAS:Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities.
Formula:C18H25N3OPurezza:98%Colore e forma:SolidPeso molecolare:299.41Nafazatrom
CAS:Nafazatrom: pyrazolinone lipoxygenase inhibitor, anticancer & antithrombotic, boosts PGI2, reduces arrhythmias.Formula:C16H16N2O2Colore e forma:SolidPeso molecolare:268.3115(S)-HETrE
CAS:15(S)-HETrE, a 15-lipoxygenated DGLA derivative, inhibits human 5-LO with IC50 of 4.6μM; 5% as effective in RBL cells.Formula:C20H34O3Colore e forma:SolidPeso molecolare:322.48AHR-5333 mandelate
CAS:AHR-5333 mandelate is an anti-allergy agent preventing anaphylaxis and skin hypersensitivity; inhibits 5-HETE, LTB4, LTC4 synthesis.Formula:C38H41F2NO7Colore e forma:SolidPeso molecolare:661.7413(S)-HpOTrE(γ)
CAS:13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid.Formula:C18H30O4Colore e forma:SolidPeso molecolare:310.43
